CLETOQUINE

Details

Stereochemistry	RACEMIC
Molecular Formula	C16H22ClN3O
Molecular Weight	307.818
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC(CCCNCCO)NC1=CC=NC2=C1C=CC(Cl)=C2

InChI

InChIKey=XFICNUNWUREFDP-UHFFFAOYSA-N

InChI=1S/C16H22ClN3O/c1-12(3-2-7-18-9-10-21)20-15-6-8-19-16-11-13(17)4-5-14(15)16/h4-6,8,11-12,18,21H,2-3,7,9-10H2,1H3,(H,19,20)

HIDE SMILES / InChI

Molecular Formula	C16H22ClN3O
Molecular Weight	307.818
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/28031899

Cletoquine is a metabolite of a disease-modifying anti-rheumatic and antimalarial drug hydroxychloroquine. It is produced by oxidative N-deethylation of hydroxychloroquine.

Approval Year

PubMed

Title	Date	PubMed
Identification and characterization of process related impurities in chloroquine and hydroxychloroquine by LC/IT/MS, LC/TOF/MS and NMR.	2009 May 1	19201565

Substance Class	Chemical Created by `admin` on `Sat Dec 16 17:07:14 UTC 2023` Edited by `admin` on `Sat Dec 16 17:07:14 UTC 2023`
Record UNII	83CVD213TU
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

CLETOQUINE

Official Name

English

cletoquine [INN]

Common Name

English

DESETHYLHYDROXYCHLOROQUINE

Common Name

English

GNF-PF-1952

Code

English

2-((4-((7-CHLORO-4-QUINOLYL)AMINO)PENTYL)AMINO)ETHANOL

Systematic Name

English

(±)-DESETHYLHYDROXYCHLOROQUINE

Common Name

English

HYDROXYCHLOROQUINE SULFATE IMPURITY C [EP IMPURITY]

Common Name

English

2-((4-((7-CHLOROQUINOLIN-4-YL)AMINO)PENTYL)AMINO)ETHAN-1-OL

Systematic Name

English

Code System Code Type Description

INN

2583