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Details

Stereochemistry ABSOLUTE
Molecular Formula C22H30O
Molecular Weight 310.473
Optical Activity UNSPECIFIED
Defined Stereocenters 6 / 6
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of DESOGESTREL

SMILES

CC[C@]12CC(=C)[C@H]3[C@@H](CCC4=CCCC[C@H]34)[C@@H]1CC[C@@]2(O)C#C

InChI

InChIKey=RPLCPCMSCLEKRS-BPIQYHPVSA-N
InChI=1S/C22H30O/c1-4-21-14-15(3)20-17-9-7-6-8-16(17)10-11-18(20)19(21)12-13-22(21,23)5-2/h2,8,17-20,23H,3-4,6-7,9-14H2,1H3/t17-,18-,19-,20+,21-,22-/m0/s1

HIDE SMILES / InChI

Molecular Formula C22H30O
Molecular Weight 310.473
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry
Defined Stereocenters 6 / 6
E/Z Centers 0
Optical Activity UNSPECIFIED

Description

Desogestrel is a prodrug of etonogestrel (3-keto-desogestrel) which was approved as oral contraceptove medicine. Desogestrel acts selectively binding to progesterone receptor and enchancing its activity.

Originator

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
Conditions
PubMed

PubMed

TitleDatePubMed
Implanon: when is the ideal time to insert?
2001 Jul
Editor's reply.
2002 Dec
Implanon.
2002 Dec
Randomized controlled study of the influence of two low estrogen dose oral contraceptives containing gestodene or desogestrel on carbohydrate metabolism.
2002 Dec
Primary dysmenorrhea treatment with a desogestrel-containing low-dose oral contraceptive.
2002 Dec
Investigation of a novel preparation of testosterone decanoate in men: pharmacokinetics and spermatogenic suppression with etonogestrel implants.
2002 Nov
Persistent vaginal bleeding in a patient with a broken Implanon.
2002 Oct
An assessment of the use of Implanon in three community services.
2002 Oct
Bleeding problems and progestogen-only contraception.
2002 Oct
Auditory brainstem response in premenopausal women taking oral contraceptives.
2003 Jan
Patents

Sample Use Guides

In Vivo Use Guide
Take 1 tablet (0.15 mg desogestrel and 0.03 mg ethinyl estradiol) at the same time every day, and at intervals not exceeding 24 hours.
Route of Administration: Oral
Substance Class Chemical
Created
by admin
on Tue Mar 06 10:32:15 UTC 2018
Edited
by admin
on Tue Mar 06 10:32:15 UTC 2018
Record UNII
81K9V7M3A3
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
DESOGESTREL
EP   HSDB   INN   MART.   MI   ORANGE BOOK   USAN   USP-RS   VANDF   WHO-DD  
INN   USAN  
Official Name English
DESOGESTREL [INN]
Common Name English
DESOGESTREL [USP-RS]
Common Name English
DESOGESTREL COMPONENT OF CYCLESSA
Common Name English
ORTHO-CEPT COMPONENT DESOGESTREL
Common Name English
VELIVET COMPONENT DESOGESTREL
Common Name English
DESOGESTREL [USAN]
Common Name English
DESOGESTREL COMPONENT OF ORTHO-CEPT
Common Name English
CYCLESSA COMPONENT DESOGESTREL
Common Name English
18,19-DINORPREGN-4-EN-20-YN-17-OL, 13-ETHYL-11-METHYLENE-, (17.ALPHA.)-
Common Name English
DESOGESTREL [MART.]
Common Name English
DESOGESTREL COMPONENT OF DESOGEN
Common Name English
DESOGESTREL [EP]
Common Name English
DESOGESTREL [JAN]
Common Name English
DESOGESTREL [ORANGE BOOK]
Common Name English
ORG 2969
Code English
DESOGESTREL COMPONENT OF MIRCETTE
Common Name English
KARIVA COMPONENT DESOGESTREL
Common Name English
DESOGEN COMPONENT DESOGESTREL
Common Name English
13-ETHYL-11-METHYLENE-18,19-DINOR-17A-PREGN-4-EN-20-YN-17-OL
Common Name English
DESOGESTREL [WHO-DD]
Common Name English
DESOGESTREL COMPONENT OF KARIVA
Common Name English
DESOGESTREL [HSDB]
Common Name English
DESOGESTREL [VANDF]
Common Name English
ORG-2969
Code English
MIRCETTE COMPONENT DESOGESTREL
Common Name English
DESOGESTREL [MI]
Common Name English
DESOGESTREL COMPONENT OF VELIVET
Common Name English
Classification Tree Code System Code
WHO-ATC G03AA09
Created by admin on Tue Mar 06 10:32:15 UTC 2018 , Edited by admin on Tue Mar 06 10:32:15 UTC 2018
NDF-RT N0000011301
Created by admin on Tue Mar 06 10:32:15 UTC 2018 , Edited by admin on Tue Mar 06 10:32:15 UTC 2018
NDF-RT N0000175602
Created by admin on Tue Mar 06 10:32:15 UTC 2018 , Edited by admin on Tue Mar 06 10:32:15 UTC 2018
WHO-VATC QG03FB10
Created by admin on Tue Mar 06 10:32:15 UTC 2018 , Edited by admin on Tue Mar 06 10:32:15 UTC 2018
WHO-VATC QG03AC09
Created by admin on Tue Mar 06 10:32:15 UTC 2018 , Edited by admin on Tue Mar 06 10:32:15 UTC 2018
LIVERTOX 285
Created by admin on Tue Mar 06 10:32:15 UTC 2018 , Edited by admin on Tue Mar 06 10:32:15 UTC 2018
WHO-VATC QG03AB05
Created by admin on Tue Mar 06 10:32:15 UTC 2018 , Edited by admin on Tue Mar 06 10:32:15 UTC 2018
WHO-ATC G03FB10
Created by admin on Tue Mar 06 10:32:15 UTC 2018 , Edited by admin on Tue Mar 06 10:32:15 UTC 2018
WHO-ATC G03AC09
Created by admin on Tue Mar 06 10:32:15 UTC 2018 , Edited by admin on Tue Mar 06 10:32:15 UTC 2018
WHO-ATC G03AB05
Created by admin on Tue Mar 06 10:32:15 UTC 2018 , Edited by admin on Tue Mar 06 10:32:15 UTC 2018
WHO-VATC QG03AA09
Created by admin on Tue Mar 06 10:32:15 UTC 2018 , Edited by admin on Tue Mar 06 10:32:15 UTC 2018
Code System Code Type Description
MERCK INDEX
M4198
Created by admin on Tue Mar 06 10:32:15 UTC 2018 , Edited by admin on Tue Mar 06 10:32:15 UTC 2018
PRIMARY Merck Index
HSDB
54024-22-5
Created by admin on Tue Mar 06 10:32:15 UTC 2018 , Edited by admin on Tue Mar 06 10:32:15 UTC 2018
PRIMARY
IUPHAR
7065
Created by admin on Tue Mar 06 10:32:15 UTC 2018 , Edited by admin on Tue Mar 06 10:32:15 UTC 2018
PRIMARY
INN
4384
Created by admin on Tue Mar 06 10:32:15 UTC 2018 , Edited by admin on Tue Mar 06 10:32:15 UTC 2018
PRIMARY
CAS
54024-22-5
Created by admin on Tue Mar 06 10:32:15 UTC 2018 , Edited by admin on Tue Mar 06 10:32:15 UTC 2018
PRIMARY
WIKIPEDIA
DESOGESTREL
Created by admin on Tue Mar 06 10:32:15 UTC 2018 , Edited by admin on Tue Mar 06 10:32:15 UTC 2018
PRIMARY
ChEMBL
CHEMBL1533
Created by admin on Tue Mar 06 10:32:15 UTC 2018 , Edited by admin on Tue Mar 06 10:32:15 UTC 2018
PRIMARY
NCI_THESAURUS
C47476
Created by admin on Tue Mar 06 10:32:15 UTC 2018 , Edited by admin on Tue Mar 06 10:32:15 UTC 2018
PRIMARY
MESH
D017135
Created by admin on Tue Mar 06 10:32:15 UTC 2018 , Edited by admin on Tue Mar 06 10:32:15 UTC 2018
PRIMARY
DRUG BANK
DB00304
Created by admin on Tue Mar 06 10:32:15 UTC 2018 , Edited by admin on Tue Mar 06 10:32:15 UTC 2018
PRIMARY
ECHA (EC/EINECS)
258-929-4
Created by admin on Tue Mar 06 10:32:15 UTC 2018 , Edited by admin on Tue Mar 06 10:32:15 UTC 2018
PRIMARY
LactMed
54024-22-5
Created by admin on Tue Mar 06 10:32:15 UTC 2018 , Edited by admin on Tue Mar 06 10:32:15 UTC 2018
PRIMARY
EPA CompTox
54024-22-5
Created by admin on Tue Mar 06 10:32:15 UTC 2018 , Edited by admin on Tue Mar 06 10:32:15 UTC 2018
PRIMARY
RXCUI
22656
Created by admin on Tue Mar 06 10:32:15 UTC 2018 , Edited by admin on Tue Mar 06 10:32:15 UTC 2018
PRIMARY RxNorm
EVMPD
SUB07003MIG
Created by admin on Tue Mar 06 10:32:15 UTC 2018 , Edited by admin on Tue Mar 06 10:32:15 UTC 2018
PRIMARY
PUBCHEM
40973
Created by admin on Tue Mar 06 10:32:15 UTC 2018 , Edited by admin on Tue Mar 06 10:32:15 UTC 2018
PRIMARY SWITZERF
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