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Details

Stereochemistry ABSOLUTE
Molecular Formula C6H9O7.Na
Molecular Weight 216.1212
Optical Activity UNSPECIFIED
Defined Stereocenters 4 / 4
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of SODIUM GALACTURONATE

SMILES

[Na+].O[C@@H](C=O)[C@@H](O)[C@@H](O)[C@H](O)C([O-])=O

InChI

InChIKey=WNFHGZLVUQBPMA-RMTXHFLUSA-M
InChI=1S/C6H10O7.Na/c7-1-2(8)3(9)4(10)5(11)6(12)13;/h1-5,8-11H,(H,12,13);/q;+1/p-1/t2-,3+,4+,5-;/m0./s1

HIDE SMILES / InChI

Molecular Formula Na
Molecular Weight 22.98976928
Charge 1
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula C6H9O7
Molecular Weight 193.1315
Charge -1
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 4 / 4
E/Z Centers 0
Optical Activity UNSPECIFIED

Description

D-Galacturonic acid is the main constituent of pectin, a naturally abundant compound. It is the monobasic acid resulting from oxidation of the primary alcohol group of D-galactose to carboxyl. D-Galacturonic acid prepared from pectin can be used to synthesize vitamin C. Native pectin is a mixture of polysaccharides, with the major component a polymer of -D-galacturonic acid. Pectin has numerous other medical and pharmaceutical uses, for example in combination with plant hemicelluloses and lignin, may be useful dietary constituents in preventing coronary heart disease, diverticular disease, ulcerative colitis, and a variety of other Western diseases. Pectin, a representative diety fibre, is a gelatinous substance derived from the cell walls of fruits and some plants and contains galacturonan, consisting of mostly long-chain D-galacturonic acids combined into units by α-1,4 linkages. As a kind of soluble dietary fiber, pectin has been proved of controlling glucose and blood lipids. It slows rapid infusion of the liquid meal into the gut by delaying gastric emptying.

Approval Year

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Unknown

PubMed

Sample Use Guides

In Vivo Use Guide
Guinea pigs: The animals were divided into three groups: Group I, positivecontrols; Group II, negative controls; Group III, experimental,with three different methods of administering the d-galacturonicacid-Group III-a, orally, by pipette (5 mg); Group III-b, subcutaneousinjection (5 mg); Group III-c, intraperitoneal injection (10 mg). Three of thepositive controls were given, in addition to their regular diet,5 mg of d-galacturonic acid daily.
Route of Administration: Other
In Vitro Use Guide
Galacturonic acid at 2 mM induced the production of some of the pectic enzymes by Botrytis cinerea. At 10 mM and above, however, it repressed PG2 and the subsequent production of the whole pectic isoenzyme complex, indicating a feedback repression.
Substance Class Chemical
Record UNII
7NBJ9PP7XF
Record Status Validated (UNII)
Record Version