Details
Stereochemistry | ABSOLUTE |
Molecular Formula | C6H10O7 |
Molecular Weight | 194.1394 |
Optical Activity | UNSPECIFIED |
Defined Stereocenters | 4 / 4 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
O[C@@H](C=O)[C@@H](O)[C@@H](O)[C@H](O)C(O)=O
InChI
InChIKey=IAJILQKETJEXLJ-RSJOWCBRSA-N
InChI=1S/C6H10O7/c7-1-2(8)3(9)4(10)5(11)6(12)13/h1-5,8-11H,(H,12,13)/t2-,3+,4+,5-/m0/s1
Molecular Formula | C6H10O7 |
Molecular Weight | 194.1394 |
Charge | 0 |
Count |
|
Stereochemistry | ABSOLUTE |
Additional Stereochemistry | No |
Defined Stereocenters | 4 / 4 |
E/Z Centers | 0 |
Optical Activity | UNSPECIFIED |
D-Galacturonic acid is the main constituent of pectin, a naturally abundant compound. It is the monobasic acid resulting from oxidation of the primary alcohol group of D-galactose to carboxyl. D-Galacturonic acid prepared from pectin can be used to synthesize vitamin C. Native pectin is a mixture of polysaccharides, with the major component a polymer of -D-galacturonic acid. Pectin has numerous other medical and pharmaceutical uses, for example in combination with plant hemicelluloses and lignin, may be useful dietary constituents in preventing coronary heart disease, diverticular disease, ulcerative colitis, and a variety of other Western diseases. Pectin, a representative diety fibre, is a gelatinous substance derived from the cell walls of fruits and some plants and contains galacturonan, consisting of mostly long-chain D-galacturonic acids combined into units by α-1,4 linkages. As a kind of soluble dietary fiber, pectin has been proved of controlling glucose and blood lipids. It slows rapid infusion of the liquid meal into the gut by delaying gastric emptying.
Approval Year
PubMed
Title | Date | PubMed |
---|---|---|
Comparative study of mupirocin and sodium fucidate in the prophylaxis of exit-site infections in CAPD patients. | 2003 Nov-Dec |
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Purification and biochemical characterization of polygalacturonases produced by Aureobasidium pullulans. | 2005 Jan-Feb |
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Oligogalacturonate hydrolase from carrot roots. | 2005 Nov-Dec |
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Structure of a novel lipid A obtained from the lipopolysaccharide of Caulobacter crescentus. | 2008 Feb |
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Wound healing evaluation of sodium fucidate-loaded polyvinylalcohol/sodium carboxymethylcellulose-based wound dressing. | 2010 Jul |
Patents
Sample Use Guides
In Vivo Use Guide
Sources: http://www.jbc.org/content/110/2/279.full.pdf
Guinea pigs: The animals were divided into three groups: Group I, positivecontrols; Group II, negative controls; Group III, experimental,with three different methods of administering the d-galacturonicacid-Group III-a, orally, by pipette (5 mg); Group III-b, subcutaneousinjection (5 mg); Group III-c, intraperitoneal injection (10 mg). Three of thepositive controls were given, in addition to their regular diet,5 mg of d-galacturonic acid daily.
Route of Administration:
Other
Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 13:39:55 GMT 2023
by
admin
on
Sat Dec 16 13:39:55 GMT 2023
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Record UNII |
2ENU0N1DRP
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Record Status |
Validated (UNII)
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Record Version |
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m5637
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D-Galacturonic acid
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47962
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84740
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DTXSID001015577
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685-73-4
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211-682-6
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4153
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Related Record | Type | Details | ||
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SALT/SOLVATE -> PARENT |