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Details

Stereochemistry ACHIRAL
Molecular Formula O4S
Molecular Weight 96.0637
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge -2

SHOW SMILES / InChI
Structure of SULFATE ION

SMILES

O=S(=O)([O-])[O-]

InChI

InChIKey=QAOWNCQODCNURD-UHFFFAOYSA-L
InChI=1S/H2O4S/c1-5(2,3)4/h(H2,1,2,3,4)/p-2

HIDE SMILES / InChI

Molecular Formula H2O4S
Molecular Weight 98.0796
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

SULFATE (as sodium sulfate, potassium sulfate, and magnesium sulfate) is a component of SUPREP Bowel Prep Kit. It is an osmotic laxative indicated for cleansing of the colon in preparation for colonoscopy in adults. Sulfate salts provide sulfate anions, which are poorly absorbed. The osmotic effect of unabsorbed sulfate anions and the associated cations causes water to be retained within the gastrointestinal tract. SUPREP Bowel Prep Kit, when ingested with a large volume of water, produces copious watery diarrhea.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Palliative
SUPREP Bowel Prep Kit

Approved Use

SUPREP Bowel Prep Kit is an osmotic laxative indicated for cleansing of the colon in preparation for colonoscopy in adults.

Launch Date

1.28096639E12
PubMed

PubMed

TitleDatePubMed
Sodium dodecyl sulphate electrophoresis of urinary proteins.
1991 Sep 13
Patterns of sulphation in heparan sulphate: polymorphism based on a common structural theme.
1992 Apr
Heparan sulphate in the binding and activation of basic fibroblast growth factor.
1992 Dec
Keratan sulphate--a 'reserve' polysaccharide?
1994 Apr
The osmotic and intrinsic mechanisms of the pharmacological laxative action of oral high doses of magnesium sulphate. Importance of the release of digestive polypeptides and nitric oxide.
1996 Jun
Structure-activity relationship of heparan sulphate.
1997 Nov
Heparan sulphate proteoglycan and wound healing in skin.
1997 Nov
Dopamine sulphate: an enigma resolved.
1999 Apr
The use of magnesium sulphate in the intensive care management of an Asian patient with tetanus.
1999 Jul
Magnesium sulphate versus phenytoin for eclampsia.
2000
Magnesium sulphate versus diazepam for eclampsia.
2000
Specificities of heparan sulphate proteoglycans in developmental processes.
2000 Apr 13
Magnesium sulphate for eclampsia: putting the evidence into clinical practice.
2000 Jun
Regulation of sulfate transport and synthesis of sulfur-containing amino acids.
2000 Jun
Herpes simplex virus: discovering the link between heparan sulphate and hereditary bone tumours.
2000 Nov-Dec
Dermatan sulphate as an antithrombotic drug.
2002 Sep-Dec
Magnesium sulphate versus phenytoin for eclampsia.
2003
Magnesium sulphate versus diazepam for eclampsia.
2003
Glucosaminyl N-deacetylase/N-sulphotransferases in heparan sulphate biosynthesis and biology.
2003 Apr
Chondroitin sulphate proteoglycans: preventing plasticity or protecting the CNS?
2004 Jan
[The extracellular matrix of the central nervous system: chondroitin sulphate type proteoglycans and neural repair].
2004 May 1-15
Chondroitin sulphate: antioxidant properties and beneficial effects.
2006 Dec
The role of heparan sulphate in inflammation.
2006 Sep
Overcoming chondroitin sulphate proteoglycan inhibition of axon growth in the injured brain: lessons from chondroitinase ABC.
2007
[Therapy of osteoarthritis crystalline glucosamine sulphate/a review of the clinical effcacy].
2007
Evaluation of formocresol versus ferric sulphate primary molar pulpotomy: a systematic review and meta-analysis.
2007 Oct
Patents

Sample Use Guides

Split-Dose (2-Day) Regimen: The evening before colonoscopy: dilute one bottle with water to a total volume of 16 oz. (up to the fill line) and drink the entire amount. Drink 32 ounces of water over the next hour. Next morning: repeat both steps using the second bottle. Complete preparation at least 2 hours before colonoscopy or as directed by a physician.
Route of Administration: Oral
Substance Class Chemical
Created
by admin
on Sat Jun 26 05:15:14 UTC 2021
Edited
by admin
on Sat Jun 26 05:15:14 UTC 2021
Record UNII
7IS9N8KPMG
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
SULFATE ION
Common Name English
SULFATE(2-)
Common Name English
SULPHATE
Systematic Name English
SULPHATE ION
Common Name English
SULFATE
VANDF  
Systematic Name English
SULPHATE(2-)
Common Name English
SULFATE [VANDF]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C597
Created by admin on Sat Jun 26 05:15:15 UTC 2021 , Edited by admin on Sat Jun 26 05:15:15 UTC 2021
LOINC 39576-4
Created by admin on Sat Jun 26 05:15:15 UTC 2021 , Edited by admin on Sat Jun 26 05:15:15 UTC 2021
LOINC 20973-4
Created by admin on Sat Jun 26 05:15:15 UTC 2021 , Edited by admin on Sat Jun 26 05:15:15 UTC 2021
LOINC 2975-1
Created by admin on Sat Jun 26 05:15:15 UTC 2021 , Edited by admin on Sat Jun 26 05:15:15 UTC 2021
LOINC 9486-2
Created by admin on Sat Jun 26 05:15:15 UTC 2021 , Edited by admin on Sat Jun 26 05:15:15 UTC 2021
LOINC 12920-5
Created by admin on Sat Jun 26 05:15:15 UTC 2021 , Edited by admin on Sat Jun 26 05:15:15 UTC 2021
LOINC 20974-2
Created by admin on Sat Jun 26 05:15:15 UTC 2021 , Edited by admin on Sat Jun 26 05:15:15 UTC 2021
DSLD 143 (Number of products:47)
Created by admin on Sat Jun 26 05:15:15 UTC 2021 , Edited by admin on Sat Jun 26 05:15:15 UTC 2021
LOINC 26889-6
Created by admin on Sat Jun 26 05:15:15 UTC 2021 , Edited by admin on Sat Jun 26 05:15:15 UTC 2021
LOINC 26888-8
Created by admin on Sat Jun 26 05:15:15 UTC 2021 , Edited by admin on Sat Jun 26 05:15:15 UTC 2021
LOINC 43754-1
Created by admin on Sat Jun 26 05:15:15 UTC 2021 , Edited by admin on Sat Jun 26 05:15:15 UTC 2021
NDF-RT N0000175811
Created by admin on Sat Jun 26 05:15:15 UTC 2021 , Edited by admin on Sat Jun 26 05:15:15 UTC 2021
LOINC 17666-9
Created by admin on Sat Jun 26 05:15:15 UTC 2021 , Edited by admin on Sat Jun 26 05:15:15 UTC 2021
Code System Code Type Description
NCI_THESAURUS
C76207
Created by admin on Sat Jun 26 05:15:15 UTC 2021 , Edited by admin on Sat Jun 26 05:15:15 UTC 2021
PRIMARY
EPA CompTox
14808-79-8
Created by admin on Sat Jun 26 05:15:15 UTC 2021 , Edited by admin on Sat Jun 26 05:15:15 UTC 2021
PRIMARY
PUBCHEM
1117
Created by admin on Sat Jun 26 05:15:15 UTC 2021 , Edited by admin on Sat Jun 26 05:15:15 UTC 2021
PRIMARY
RXCUI
1426598
Created by admin on Sat Jun 26 05:15:15 UTC 2021 , Edited by admin on Sat Jun 26 05:15:15 UTC 2021
PRIMARY RxNorm
CAS
14808-79-8
Created by admin on Sat Jun 26 05:15:15 UTC 2021 , Edited by admin on Sat Jun 26 05:15:15 UTC 2021
PRIMARY
FDA UNII
7IS9N8KPMG
Created by admin on Sat Jun 26 05:15:15 UTC 2021 , Edited by admin on Sat Jun 26 05:15:15 UTC 2021
PRIMARY
EVMPD
SUB22774
Created by admin on Sat Jun 26 05:15:15 UTC 2021 , Edited by admin on Sat Jun 26 05:15:15 UTC 2021
PRIMARY
DRUG BANK
DB14546
Created by admin on Sat Jun 26 05:15:15 UTC 2021 , Edited by admin on Sat Jun 26 05:15:15 UTC 2021
PRIMARY
WIKIPEDIA
SULFATE
Created by admin on Sat Jun 26 05:15:15 UTC 2021 , Edited by admin on Sat Jun 26 05:15:15 UTC 2021
PRIMARY
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