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Details

Stereochemistry ACHIRAL
Molecular Formula O4S
Molecular Weight 96.063
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge -2

SHOW SMILES / InChI
Structure of SULFATE ION

SMILES

[O-]S([O-])(=O)=O

InChI

InChIKey=QAOWNCQODCNURD-UHFFFAOYSA-L
InChI=1S/H2O4S/c1-5(2,3)4/h(H2,1,2,3,4)/p-2

HIDE SMILES / InChI

Molecular Formula H2O4S
Molecular Weight 98.078
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

SULFATE (as sodium sulfate, potassium sulfate, and magnesium sulfate) is a component of SUPREP Bowel Prep Kit. It is an osmotic laxative indicated for cleansing of the colon in preparation for colonoscopy in adults. Sulfate salts provide sulfate anions, which are poorly absorbed. The osmotic effect of unabsorbed sulfate anions and the associated cations causes water to be retained within the gastrointestinal tract. SUPREP Bowel Prep Kit, when ingested with a large volume of water, produces copious watery diarrhea.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Palliative
SUPREP Bowel Prep Kit

Approved Use

SUPREP Bowel Prep Kit is an osmotic laxative indicated for cleansing of the colon in preparation for colonoscopy in adults.

Launch Date

1.28096639E12
PubMed

PubMed

TitleDatePubMed
Management of autonomic dysfunction in severe tetanus: the use of magnesium sulphate and clonidine.
1990
Sodium dodecyl sulphate electrophoresis of urinary proteins.
1991 Sep 13
Patterns of sulphation in heparan sulphate: polymorphism based on a common structural theme.
1992 Apr
Heparan sulphate in the binding and activation of basic fibroblast growth factor.
1992 Dec
Keratan sulphate--a 'reserve' polysaccharide?
1994 Apr
Renal and small intestinal sodium-dependent symporters of phosphate and sulphate.
1994 Nov
Dextran sulphate induces a PKC and actin independent internalisation of CD4.
1994 Sep
The osmotic and intrinsic mechanisms of the pharmacological laxative action of oral high doses of magnesium sulphate. Importance of the release of digestive polypeptides and nitric oxide.
1996 Jun
The role of stromal cell heparan sulphate in regulating haemopoiesis.
1996 May
Dehydroepiandrosterone, dehydroepiandrosterone sulphate and cardiovascular disease.
1996 Sep
Heparan sulphate.
1997 May
Heparan sulphate. Regulation of growth factors in the mammary gland.
2000
Magnesium sulphate for eclampsia: putting the evidence into clinical practice.
2000 Jun
Magnesium sulphate versus lytic cocktail for eclampsia.
2001
Chondroitin sulphate proteoglycans in the CNS injury response.
2002
[Skin patch test with nickel sulphate--an attempt of broader interpretation of the results].
2002 Aug
Magnesium sulphate versus phenytoin for eclampsia.
2003
Magnesium sulphate versus diazepam for eclampsia.
2003
Glucosaminyl N-deacetylase/N-sulphotransferases in heparan sulphate biosynthesis and biology.
2003 Apr
Chondroitin sulphate proteoglycans in the central nervous system: changes and synthesis after injury.
2003 Apr
Heparan sulphate N-sulphotransferase activity: reaction mechanism and substrate recognition.
2003 Apr
Are low dehydroepiandrosterone sulphate levels predictive for cardiovascular diseases? A review of prospective and retrospective studies.
2003 Oct
Molecular recognition by LARGE is essential for expression of functional dystroglycan.
2004 Jun 25
Biotechnological engineering of heparin/heparan sulphate: a novel area of multi-target drug discovery.
2005
Evidence and practice: the magnesium sulphate story.
2005 Feb
Heparan sulphate proteoglycans: the sweet side of development.
2005 Jul
Chondroitin sulphate: antioxidant properties and beneficial effects.
2006 Dec
The role of heparan sulphate proteoglycans in angiogenesis.
2006 Jun
Insights into the role of heparan sulphate in fibroblast growth factor signalling.
2006 Jun
Dietary acidification enhances phosphorus digestibility but decreases H+/K+-ATPase expression in rainbow trout.
2006 Oct
The role of heparan sulphate in inflammation.
2006 Sep
Overcoming chondroitin sulphate proteoglycan inhibition of axon growth in the injured brain: lessons from chondroitinase ABC.
2007
[Therapy of osteoarthritis crystalline glucosamine sulphate/a review of the clinical effcacy].
2007
Heparan sulphate proteoglycans fine-tune mammalian physiology.
2007 Apr 26
Magnesium sulphate for women at risk of preterm birth for neuroprotection of the fetus.
2007 Jul 18
Evaluation of formocresol versus ferric sulphate primary molar pulpotomy: a systematic review and meta-analysis.
2007 Oct
Cholesterol sulfate as a potential inhibitor of hepatitis C virus NS3 helicase.
2014 Apr
Patents

Sample Use Guides

Split-Dose (2-Day) Regimen: The evening before colonoscopy: dilute one bottle with water to a total volume of 16 oz. (up to the fill line) and drink the entire amount. Drink 32 ounces of water over the next hour. Next morning: repeat both steps using the second bottle. Complete preparation at least 2 hours before colonoscopy or as directed by a physician.
Route of Administration: Oral
Substance Class Chemical
Created
by admin
on Fri Dec 15 16:09:18 UTC 2023
Edited
by admin
on Fri Dec 15 16:09:18 UTC 2023
Record UNII
7IS9N8KPMG
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
SULFATE ION
Common Name English
SULFATE(2-)
Common Name English
SULPHATE
Systematic Name English
SULPHATE ION
Common Name English
SULFATE
VANDF  
Systematic Name English
SULPHATE(2-)
Common Name English
SULFATE [VANDF]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C597
Created by admin on Fri Dec 15 16:09:19 UTC 2023 , Edited by admin on Fri Dec 15 16:09:19 UTC 2023
LOINC 39576-4
Created by admin on Fri Dec 15 16:09:19 UTC 2023 , Edited by admin on Fri Dec 15 16:09:19 UTC 2023
LOINC 20973-4
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LOINC 2975-1
Created by admin on Fri Dec 15 16:09:19 UTC 2023 , Edited by admin on Fri Dec 15 16:09:19 UTC 2023
LOINC 9486-2
Created by admin on Fri Dec 15 16:09:19 UTC 2023 , Edited by admin on Fri Dec 15 16:09:19 UTC 2023
LOINC 12920-5
Created by admin on Fri Dec 15 16:09:19 UTC 2023 , Edited by admin on Fri Dec 15 16:09:19 UTC 2023
LOINC 20974-2
Created by admin on Fri Dec 15 16:09:19 UTC 2023 , Edited by admin on Fri Dec 15 16:09:19 UTC 2023
DSLD 143 (Number of products:47)
Created by admin on Fri Dec 15 16:09:19 UTC 2023 , Edited by admin on Fri Dec 15 16:09:19 UTC 2023
LOINC 26889-6
Created by admin on Fri Dec 15 16:09:19 UTC 2023 , Edited by admin on Fri Dec 15 16:09:19 UTC 2023
LOINC 26888-8
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LOINC 43754-1
Created by admin on Fri Dec 15 16:09:19 UTC 2023 , Edited by admin on Fri Dec 15 16:09:19 UTC 2023
NDF-RT N0000175811
Created by admin on Fri Dec 15 16:09:19 UTC 2023 , Edited by admin on Fri Dec 15 16:09:19 UTC 2023
LOINC 17666-9
Created by admin on Fri Dec 15 16:09:19 UTC 2023 , Edited by admin on Fri Dec 15 16:09:19 UTC 2023
Code System Code Type Description
NCI_THESAURUS
C76207
Created by admin on Fri Dec 15 16:09:19 UTC 2023 , Edited by admin on Fri Dec 15 16:09:19 UTC 2023
PRIMARY
EPA CompTox
DTXSID3042425
Created by admin on Fri Dec 15 16:09:19 UTC 2023 , Edited by admin on Fri Dec 15 16:09:19 UTC 2023
PRIMARY
PUBCHEM
1117
Created by admin on Fri Dec 15 16:09:19 UTC 2023 , Edited by admin on Fri Dec 15 16:09:19 UTC 2023
PRIMARY
SMS_ID
100000089045
Created by admin on Fri Dec 15 16:09:19 UTC 2023 , Edited by admin on Fri Dec 15 16:09:19 UTC 2023
PRIMARY
CHEBI
16189
Created by admin on Fri Dec 15 16:09:19 UTC 2023 , Edited by admin on Fri Dec 15 16:09:19 UTC 2023
PRIMARY
RXCUI
1426598
Created by admin on Fri Dec 15 16:09:19 UTC 2023 , Edited by admin on Fri Dec 15 16:09:19 UTC 2023
PRIMARY RxNorm
CAS
14808-79-8
Created by admin on Fri Dec 15 16:09:19 UTC 2023 , Edited by admin on Fri Dec 15 16:09:19 UTC 2023
PRIMARY
FDA UNII
7IS9N8KPMG
Created by admin on Fri Dec 15 16:09:19 UTC 2023 , Edited by admin on Fri Dec 15 16:09:19 UTC 2023
PRIMARY
EVMPD
SUB22774
Created by admin on Fri Dec 15 16:09:19 UTC 2023 , Edited by admin on Fri Dec 15 16:09:19 UTC 2023
PRIMARY
DAILYMED
7IS9N8KPMG
Created by admin on Fri Dec 15 16:09:19 UTC 2023 , Edited by admin on Fri Dec 15 16:09:19 UTC 2023
PRIMARY
DRUG BANK
DB14546
Created by admin on Fri Dec 15 16:09:19 UTC 2023 , Edited by admin on Fri Dec 15 16:09:19 UTC 2023
PRIMARY
WIKIPEDIA
SULFATE
Created by admin on Fri Dec 15 16:09:19 UTC 2023 , Edited by admin on Fri Dec 15 16:09:19 UTC 2023
PRIMARY
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