U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 14:23:33 GMT 2023
Edited
by admin
on Sat Dec 16 14:23:33 GMT 2023
Protein Type MONOCLONAL ANTIBODY CONJUGATE
Protein Sub Type IGG1
Sequence Origin HUMANIZED MOUSE
Sequence Type COMPLETE
Record UNII
7HW5CX6OD5
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
Tarcocimab Tedromer
INN   USAN  
Official Name English
OG1953
Code English
TARCOCIMAB TEDROMER [USAN]
Common Name English
Immunoglobulin G1 [240-alanine,241-alanine,243-alanine,449-cysteine], anti-(human vascular endothelial growth factor A) (human-Mus musculus monoclonal OG1950 g1-chain), disulfide with human-Mus musculus monoclonal OG1950 k-chain, (232®232'),(235®235')-
Common Name English
OG-1953
Code English
Immunoglobulin G1-kappa, anti-[Homo sapiens VEGFA (vascular endothelial growth factor A, VEGF-A, VEGF)], humanized monoclonal antibody, conjugated via a linker to a nonaantennary dendrimer with phosphorylcholine polymer end groups; gamma1 heavy chain hum
Common Name English
tarcocimab tedromer [INN]
Common Name English
KSI-301
Code English
Code System Code Type Description
NCI_THESAURUS
C188530
Created by admin on Sat Dec 16 14:23:33 GMT 2023 , Edited by admin on Sat Dec 16 14:23:33 GMT 2023
PRIMARY
INN
11774
Created by admin on Sat Dec 16 14:23:33 GMT 2023 , Edited by admin on Sat Dec 16 14:23:33 GMT 2023
PRIMARY
CAS
2411896-53-0
Created by admin on Sat Dec 16 14:23:33 GMT 2023 , Edited by admin on Sat Dec 16 14:23:33 GMT 2023
PRIMARY
FDA UNII
7HW5CX6OD5
Created by admin on Sat Dec 16 14:23:33 GMT 2023 , Edited by admin on Sat Dec 16 14:23:33 GMT 2023
PRIMARY
USAN
KL-251
Created by admin on Sat Dec 16 14:23:33 GMT 2023 , Edited by admin on Sat Dec 16 14:23:33 GMT 2023
PRIMARY
From To
1_22 1_96
1_449 2_22
2_96 2_150
2_206 4_134
2_235 2_267
1_150 1_206
2_327 2_373
2_431 2_449
3_23 3_88
3_194 3_214
4_23 4_88
1_226 3_134
1_232 2_226
1_235 2_232
1_267 1_327
1_373 1_431
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_303
N 2_303
Related Record Type Details
TARGET -> INHIBITOR
PARENT -> CONJUGATE
Related Record Type Details
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT:NUMBER AVERAGE CHEMICAL