Tarcocimab

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Sat Dec 16 18:52:46 UTC 2023` Edited by `admin` on `Sat Dec 16 18:52:46 UTC 2023`
Protein Type	MONOCLONAL ANTIBODY CONJUGATE
Protein Sub Type	IGG1
Sequence Origin	HUMANIZED MOUSE
Sequence Type	COMPLETE
Record UNII	QNU3MX7NBY
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Tarcocimab

Official Name

English

Immunoglobulin G1-kappa, anti-[Homo sapiens VEGFA (vascular endothelial growth factor A, VEGF-A, VEGF)], humanized monoclonal antibody; gamma1 heavy chain humanized (1-453) [VH (Homo sapiens IGHV3- 30*02 (75.8%) -(IGHD) -IGHJ4*01 (93.3%), CDR-IMGT [8.8.1

Common Name

English

OG1950

Code

English

Immunoglobulin G1 [240-alanine,241-alanine,243-alanine,449-cysteine], anti-(human vascular endothelial growth factor A) (human-Mus musculus monoclonal OG1950 γ1-chain), disulfide with human-Mus musculus monoclonal OG1950 κ-chain,(232→232'),(235→235

Common Name

English

TARCOCIMAB [USAN]

Common Name

English

OG-1950

Code

English

tarcocimab [INN]

Common Name

English

Code System Code Type Description

NCI_THESAURUS

C184872

Created by admin on Sat Dec 16 18:52:46 UTC 2023 , Edited by admin on Sat Dec 16 18:52:46 UTC 2023

PRIMARY

USAN

KL-250

Created by admin on Sat Dec 16 18:52:46 UTC 2023 , Edited by admin on Sat Dec 16 18:52:46 UTC 2023

PRIMARY

FDA UNII

QNU3MX7NBY

Created by admin on Sat Dec 16 18:52:46 UTC 2023 , Edited by admin on Sat Dec 16 18:52:46 UTC 2023

PRIMARY

CAS

2408661-40-3

Created by admin on Sat Dec 16 18:52:46 UTC 2023 , Edited by admin on Sat Dec 16 18:52:46 UTC 2023

PRIMARY

INN

11770

Created by admin on Sat Dec 16 18:52:46 UTC 2023 , Edited by admin on Sat Dec 16 18:52:46 UTC 2023

PRIMARY

From	To
1_22	1_96
1_449	2_22
2_96	2_150
2_206	4_134
2_235	2_267
1_150	1_206
2_327	2_373
2_431	2_449
3_23	3_88
3_194	3_214
4_23	4_88
1_226	3_134
1_232	2_226
1_235	2_232
1_267	1_327
1_373	1_431

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_303
N	2_303

Related Record Type Details


					NZN256ZSV8

HUMAN VASCULAR ENDOTHELIAL GROWTH FACTOR A

TARGET->LIGAND

Amount:


					7HW5CX6OD5

Tarcocimab Tedromer

CONJUGATE -> PARENT

Amount:

Related Record Type Details


					QNU3MX7NBY

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL