U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 12:03:31 GMT 2023
Edited
by admin
on Sat Dec 16 12:03:31 GMT 2023
Protein Type RECEPTOR
Protein Sub Type
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
7H1P16DG5J
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
5-HYDROXYTRYPTAMINE RECEPTOR 4
Common Name English
SEROTONIN RECEPTOR 4
Common Name English
5-HT4
Common Name English
HTR4
Common Name English
Code System Code Type Description
FDA UNII
7H1P16DG5J
Created by admin on Sat Dec 16 12:03:33 GMT 2023 , Edited by admin on Sat Dec 16 12:03:33 GMT 2023
PRIMARY
UNIPROT
Q13639
Created by admin on Sat Dec 16 12:03:33 GMT 2023 , Edited by admin on Sat Dec 16 12:03:33 GMT 2023
PRIMARY
From To
1_93 1_184
Glycosylation Type HUMAN
Glycosylation Link Type Site
N 1_7
Related Record Type Details
PARTIAL AGONIST->TARGET
INHIBITOR -> TARGET
Kb listed
Kd
INHIBITOR -> TARGET
Ki
AGONIST -> TARGET
AGONIST -> TARGET
AGONIST -> TARGET
INHIBITOR -> TARGET
INHIBITOR
Ki
INHIBITOR -> TARGET
AGONIST -> TARGET
Interaction with the 5-HT4 receptor leads to the elevation of cyclic adenosine monophosphate (cAMP) levels in HEK293 cells
EC50
NON-INHIBITOR -> TRANSPORTER
Ki
AGONIST -> TARGET
BINDING
Ki
RADIOLIGAND->TARGET
Kd
PARTIAL AGONIST->TARGET
AGONIST -> TARGET
WEAK INHIBITOR->TARGET
INHIBITOR
Ki
RADIOLIGAND->TARGET
Kd
INHIBITOR -> TARGET
AGONIST -> TARGET
AGONIST -> TARGET
AGONIST -> TARGET
AGONIST -> TARGET
AGONIST -> TARGET
BINDING
Ki
AGONIST -> TARGET
PARTIAL AGONIST
AGONIST -> TARGET
RADIOLIGAND->TARGET
IMAGING AGENT
Ki
AGONIST -> TARGET
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT CHEMICAL