Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C22H26FN3O2 |
| Molecular Weight | 383.4591 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
NC(=O)C1=CC(F)=C([C@@H]2CCCN(C2)C(=O)C=C)C3=C1NC4=C3CCCCC4
InChI
InChIKey=NEHJPDSXWUIXGI-CYBMUJFWSA-N
InChI=1S/C22H26FN3O2/c1-2-18(27)26-10-6-7-13(12-26)19-16(23)11-15(22(24)28)21-20(19)14-8-4-3-5-9-17(14)25-21/h2,11,13,25H,1,3-10,12H2,(H2,24,28)/t13-/m1/s1
| Molecular Formula | C22H26FN3O2 |
| Molecular Weight | 383.4591 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 18:21:08 UTC 2023
by
admin
on
Sat Dec 16 18:21:08 UTC 2023
|
| Record UNII |
7BS8743F3E
|
| Record Status |
Validated (UNII)
|
| Record Version |
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-
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7BS8743F3E
Created by
admin on Sat Dec 16 18:21:08 UTC 2023 , Edited by admin on Sat Dec 16 18:21:08 UTC 2023
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2724962-58-5
Created by
admin on Sat Dec 16 18:21:08 UTC 2023 , Edited by admin on Sat Dec 16 18:21:08 UTC 2023
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12716
Created by
admin on Sat Dec 16 18:21:08 UTC 2023 , Edited by admin on Sat Dec 16 18:21:08 UTC 2023
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156888508
Created by
admin on Sat Dec 16 18:21:08 UTC 2023 , Edited by admin on Sat Dec 16 18:21:08 UTC 2023
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PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
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TARGET -> INHIBITOR |
PRECLINICAL
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| Related Record | Type | Details | ||
|---|---|---|---|---|
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ACTIVE MOIETY |
GB5121 is a selective, irreversible, orally available, small molecule inhibitor of Bruton’s tyrosine kinase (BTK) that is central nervous system (CNS) penetrant.
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