BEFURALINE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C20H20N2O2
Molecular Weight	320.385
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

O=C(N1CCN(CC2=CC=CC=C2)CC1)C3=CC4=C(O3)C=CC=C4

InChI

InChIKey=SRIJFPBZWUFLFD-UHFFFAOYSA-N

InChI=1S/C20H20N2O2/c23-20(19-14-17-8-4-5-9-18(17)24-19)22-12-10-21(11-13-22)15-16-6-2-1-3-7-16/h1-9,14H,10-13,15H2

HIDE SMILES / InChI

Molecular Formula	C20H20N2O2
Molecular Weight	320.385
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/4089015 | https://adisinsight.springer.com/drugs/800000674

Originator

Approval Year

PubMed

Title	Date	PubMed
[Synthesis and antidepressive activity study of aryl and heteroaryl carboxamides of benzylpiperazine].	2000 Jul	10915973

Sample Use Guides

In Vivo Use Guide

Befuraline, given in oral doses of between 100 and 300 mg/day improved the HDRS total score and the cognitive disturbances to a significant extent (p less than 0.01) after the first week of the treatment.

Route of Administration: Oral

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:03:05 GMT 2023` Edited by `admin` on `Fri Dec 15 16:03:05 GMT 2023`
Record UNII	787AQ35GHR
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

BEFURALINE

Official Name

English

befuraline [INN]

Common Name

English

1-(2-BENZOFURANYLCARBONYL)-4-BENZYLPIPERAZINE

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C265