BEFURALINE HYDROCHLORIDE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C20H20N2O2.ClH
Molecular Weight	356.846
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

Cl.O=C(N1CCN(CC2=CC=CC=C2)CC1)C3=CC4=C(O3)C=CC=C4

InChI

InChIKey=GMEYXHHLZUAKDY-UHFFFAOYSA-N

InChI=1S/C20H20N2O2.ClH/c23-20(19-14-17-8-4-5-9-18(17)24-19)22-12-10-21(11-13-22)15-16-6-2-1-3-7-16;/h1-9,14H,10-13,15H2;1H

HIDE SMILES / InChI

Molecular Formula	C20H20N2O2
Molecular Weight	320.385
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	ClH
Molecular Weight	36.461
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/4089015 | https://adisinsight.springer.com/drugs/800000674

Originator

Approval Year

PubMed

Title	Date	PubMed
[Open study of befuraline (DIV 154) in 64 depressive patients (author's transl)].	1977	341906
Befuraline, its safety and efficacy in depressed inpatients.	1985 Nov	4089015

Sample Use Guides

In Vivo Use Guide

Befuraline, given in oral doses of between 100 and 300 mg/day improved the HDRS total score and the cognitive disturbances to a significant extent (p less than 0.01) after the first week of the treatment.

Route of Administration: Oral

Substance Class	Chemical Created by `admin` on `Fri Dec 15 19:38:38 GMT 2023` Edited by `admin` on `Fri Dec 15 19:38:38 GMT 2023`
Record UNII	4AF205SN5K
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

BEFURALINE HYDROCHLORIDE

Common Name

English

NSC-312899

Code

English

DIV-154

Code

English

BENZOFURAN-2-YL 4-BENZYLPIPERAZIN-1-YL KETONE HYDROCHLORIDE

Systematic Name

English

BEFURALINE HCL

Common Name

English

DIV 154

Code

English

BEFURALINE HYDROCHLORIDE [MART.]

Common Name

English

Code System Code Type Description

PUBCHEM

73346