CGP-37849

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NCATS

Details

Stereochemistry	RACEMIC
Molecular Formula	C6H12NO5P
Molecular Weight	209.1369
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure of CGP-37849

Structure Search

SMILES

C\C(CP(O)(O)=O)=C/C(N)C(O)=O

InChI

InChIKey=BDYHNCZIGYIOGJ-DUXPYHPUSA-N

InChI=1S/C6H12NO5P/c1-4(3-13(10,11)12)2-5(7)6(8)9/h2,5H,3,7H2,1H3,(H,8,9)(H2,10,11,12)/b4-2+

HIDE SMILES / InChI

Molecular Formula	C6H12NO5P
Molecular Weight	209.1369
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	1
Optical Activity	( + / - )

Approval Year

Targets

Targets

Primary Target	Pharmacology	Condition	Potency
Glutamate NMDA receptor 46 Target ID: CHEMBL1907608 Sources: https://www.ncbi.nlm.nih.gov/pubmed/1533680	Antagonist 2778		35.0 nM [Ki]
Glutamate [NMDA] receptor subunit epsilon 1 2 Target ID: CHEMBL1972 Sources: https://www.ncbi.nlm.nih.gov/pubmed/16107147	Antagonist 2778		220.0 nM [IC50]

Substance Class	Chemical Created by `admin` on `Sat Dec 16 08:14:41 GMT 2023` Edited by `admin` on `Sat Dec 16 08:14:41 GMT 2023`
Record UNII	76IND1BS43
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

CGP-37849

Common Name

English

CGP-40116, (±)-

Code

English

3-PENTENOIC ACID, 2-AMINO-4-METHYL-5-PHOSPHONO-, (E)-(±)-

Systematic Name

English

CGP-40117, (±)-

Code

English

CGP 37849

Code

English

3-PENTENOIC ACID, 2-AMINO-4-METHYL-5-PHOSPHONO-, (3E)-

Systematic Name

English

Classification Tree Code System Code

WIKIPEDIA

NMDA receptor antagonist

Created by admin on Sat Dec 16 08:14:41 GMT 2023 , Edited by admin on Sat Dec 16 08:14:41 GMT 2023

Code System Code Type Description

CAS

137424-81-8

Created by admin on Sat Dec 16 08:14:41 GMT 2023 , Edited by admin on Sat Dec 16 08:14:41 GMT 2023

NON-SPECIFIC STEREOCHEMISTRY

CAS

127910-31-0

Created by admin on Sat Dec 16 08:14:41 GMT 2023 , Edited by admin on Sat Dec 16 08:14:41 GMT 2023

PRIMARY

WIKIPEDIA

CGP-37849

Created by admin on Sat Dec 16 08:14:41 GMT 2023 , Edited by admin on Sat Dec 16 08:14:41 GMT 2023

PRIMARY

PUBCHEM

5950212

Created by admin on Sat Dec 16 08:14:41 GMT 2023 , Edited by admin on Sat Dec 16 08:14:41 GMT 2023

PRIMARY

EPA CompTox

DTXSID40873634

Created by admin on Sat Dec 16 08:14:41 GMT 2023 , Edited by admin on Sat Dec 16 08:14:41 GMT 2023

PRIMARY

FDA UNII

76IND1BS43

Created by admin on Sat Dec 16 08:14:41 GMT 2023 , Edited by admin on Sat Dec 16 08:14:41 GMT 2023

PRIMARY

Related Record Type Details


					4R3XO922WS

TARGET -> INHIBITOR

Comments:

Competes with glutamate

Interaction Type:

COMPETITIVE INHIBITOR

Amount:

Related Record Type Details


					76IND1BS43

CGP-37849

ACTIVE MOIETY

Amount: