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Description

Lixisenatide (trade name Adlyxin) is a glucagon-like peptide-1 (GLP-1) receptor agonist indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.

CNS Activity

CNS Penetrant
2,554

Originator

Zealand Pharma
5

Approval Year

2016
495

Targets

Primary TargetPharmacologyConditionPotency
Glucagon-like peptide 1 receptor
4
Agonist
2,678

Conditions

ConditionModalityTargetsHighest PhaseProduct
Type 2 diabetes mellitus
259
 Palliative
Approved
8,429
ADLYXIN

PubMed

Patents

WO2012156298A1
1

Sample Use Guides

In Vivo Use Guide
The starting dose of ADLYXIN is 10 mcg subcutaneously once daily for 14 days. Increase the dose to the maintenance dose of 20 mcg once daily starting on Day 15.
Route of Administration: Other
In Vitro Use Guide
Unknown
Substance Class Protein
Protein Sub Type
Sequence Type COMPLETE
Record UNII
74O62BB01U
Record Status Validated (UNII)
Record Version
Subunit 0

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