SULMARIN

Details

Stereochemistry	ACHIRAL
Molecular Formula	C10H8O10S2
Molecular Weight	352.295
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC1=CC(=O)OC2=C1C=C(OS(O)(=O)=O)C(OS(O)(=O)=O)=C2

InChI

InChIKey=SZNQDPUZKFSCNG-UHFFFAOYSA-N

InChI=1S/C10H8O10S2/c1-5-2-10(11)18-7-4-9(20-22(15,16)17)8(3-6(5)7)19-21(12,13)14/h2-4H,1H3,(H,12,13,14)(H,15,16,17)

HIDE SMILES / InChI

Molecular Formula	C10H8O10S2
Molecular Weight	352.295
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/603704 | Bollettino - Societa Italiana di Biologia Sperimentale (1977), 53, (11), 942-6.

Sulmarin is a water-soluble coumarin derivative with vitamin P activity. In preclinical models Sulmarin facilitates excitatory transmission from parasympathetic fibers to the gastric musculature, increasing acetylcholine release. Sulmarin reduced the tone of isolated calf coronary arteries and also inhibited the contractile response of the arteries to angiotensin II amide (Hypertensin).

Originator

Approval Year

PubMed

Title	Date	PubMed
[Effect of a flavonoid (4-methylesculetin) on the response of isolated calf coronary arteries to histamine].	1977 Nov 30	603704

Patents

Substance Class	Chemical Created by `admin` on `Sat Dec 16 17:19:40 GMT 2023` Edited by `admin` on `Sat Dec 16 17:19:40 GMT 2023`
Record UNII	73W96524XT
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

SULMARIN

Official Name

English

Sulmarin [WHO-DD]

Common Name

English

M.G. 143

Code

English

SULMARIN [USAN]

Common Name

English

SULMARIN [MI]

Common Name

English

6,7-Dihydroxy-4-methylcoumarin bis(hydrogen sulfate)

Systematic Name

English

IDRO P2

Brand Name

English

sulmarin [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C45597