SULMARIN DISODIUM

Details

Stereochemistry	ACHIRAL
Molecular Formula	C10H6O10S2.2Na
Molecular Weight	396.258
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[Na+].[Na+].CC1=CC(=O)OC2=C1C=C(OS([O-])(=O)=O)C(OS([O-])(=O)=O)=C2

InChI

InChIKey=YCZIKIZDMUKKPA-UHFFFAOYSA-L

InChI=1S/C10H8O10S2.2Na/c1-5-2-10(11)18-7-4-9(20-22(15,16)17)8(3-6(5)7)19-21(12,13)14;;/h2-4H,1H3,(H,12,13,14)(H,15,16,17);;/q;2*+1/p-2

HIDE SMILES / InChI

Molecular Formula	C10H6O10S2
Molecular Weight	350.279
Charge	-2
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	Na
Molecular Weight	22.9898
Charge	1
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/603704 | Bollettino - Societa Italiana di Biologia Sperimentale (1977), 53, (11), 942-6.

Sulmarin is a water-soluble coumarin derivative with vitamin P activity. In preclinical models Sulmarin facilitates excitatory transmission from parasympathetic fibers to the gastric musculature, increasing acetylcholine release. Sulmarin reduced the tone of isolated calf coronary arteries and also inhibited the contractile response of the arteries to angiotensin II amide (Hypertensin).

Originator

Approval Year

PubMed

Title	Date	PubMed
[Effect of a flavonoid (4-methylesculetin) on the response of isolated calf coronary arteries to histamine].	1977 Nov 30	603704

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 19:05:27 GMT 2023` Edited by `admin` on `Fri Dec 15 19:05:27 GMT 2023`
Record UNII	719219P18R
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

SULMARIN DISODIUM

Common Name

English

4-METHYLESCULETOL DISULFATE DISODIUM SALT

Common Name

English

Sulmarin disodium [WHO-DD]

Common Name

English

MG 143

Code

English

2H-1-BENZOPYRAN-2-ONE, 4-METHYL-6,7-BIS(SULFOOXY)-, SODIUM SALT (1:2)

Common Name

English

MG-143

Code

English

Code System Code Type Description

EPA CompTox

DTXSID60146211