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BELIMUMAB
73B0K5S26A
US Approved Rx (2017)
First approved in 2011
General
Record Details
Names
21
Classification
6
Identifiers
18
Subunits
4
Disulfide Links
2
Relationships
1
Active Moiety
1
Characteristic Attributes
4
BELIMUMAB
73B0K5S26A
US Approved Rx (2017)
First approved in 2011
General
Approval Year
2011
587
Record Details
Substance Class
Protein
Protein Type
MONOCLONAL ANTIBODY
Protein Sub Type
IGG1
Sequence Origin
HUMAN
Sequence Type
COMPLETE
Record UNII
73B0K5S26A
Record Status
Validated (UNII)
Record Version
29
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Names
21
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5
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entries
Name
Type
Language
Name
Type
Language
BELIMUMAB
Official Name
English
BELIMUMAB [PURPLE BOOK CDER]
Common Name
English
BELIMUMAB [MART.]
Common Name
English
GSK-1550188
Code
English
HGS1006
Code
English
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4
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Classification
6
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Classification Tree
Code System
Code
Classification Tree
Code System
Code
Selective immunosuppressants
ATC
ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
IMMUNOSUPPRESSANTS
IMMUNOSUPPRESSANTS
Selective immunosuppressants
belimumab
WHO-ATC
L04AA26
Established Pharmacologic Class
Established Pharmacologic Class
[EPC]
B Lymphocyte Stimulator-specific Inhibitor
[EPC]
NDF-RT
N0000182637
Designated
ORPHAN DRUG
Designated
Treatment of systemic sclerosis
FDA ORPHAN DRUG
921522
Biological Agent
Pharmacologic Substance
[C1909]
Biological Agent
[C307]
Monoclonal Antibody
NCI_THESAURUS
C20401
Selective immunosuppressants
VATC
IMMUNOSUPPRESSANTS
IMMUNOSUPPRESSANTS
Selective immunosuppressants
belimumab
WHO-VATC
QL04AA26
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Identifiers
18
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entries
Code System
Code
Type
Description
Code System
Code
Type
Description
DRUG CENTRAL
4949
PRIMARY
USAN
OO-56
PRIMARY
WIKIPEDIA
BELIMUMAB
PRIMARY
IUPHAR
6887
PRIMARY
DAILYMED
73B0K5S26A
PRIMARY
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4
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Subunits
4
Disulfide Links
2
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From
To
From
To
1_22
1_96
2_22
2_96
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Relationships
1
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Related Record
Type
Details
Related Record
Type
Details
U1A5T521IT
TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 13B MEMBRANE FORM
TARGET -> INHIBITOR
Amount:
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Active Moiety
1
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entries
Related Record
Type
Details
Related Record
Type
Details
73B0K5S26A
BELIMUMAB
ACTIVE MOIETY
Amount:
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Characteristic Attributes
4
Name
Property Type
Amount
Referenced Substance
Defining
Parameters
References
Volume of Distribution
PHARMACOKINETIC
0.07 Liters/Kilogram (average)
Biological Half-life
PHARMACOKINETIC
19.4 days (average)
Molecular Formula
CHEMICAL
ESTIMATED
C6346H9824N1722O2010S44
MOL_WEIGHT:SEQUENCE
CHEMICAL
SEQUENCE 145414.44 Da (average)
