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Details

Stereochemistry RACEMIC
Molecular Formula C17H18N2
Molecular Weight 250.3382
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of DAZEPINIL

SMILES

CN1C(CC2=C(C=CC=C2)N=C1C)C3=CC=CC=C3

InChI

InChIKey=STDYWHYUOSSCBO-UHFFFAOYSA-N
InChI=1S/C17H18N2/c1-13-18-16-11-7-6-10-15(16)12-17(19(13)2)14-8-4-3-5-9-14/h3-11,17H,12H2,1-2H3

HIDE SMILES / InChI

Molecular Formula C17H18N2
Molecular Weight 250.3382
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 0
Optical Activity ( + / - )

Description

Dazepinil (HRP 543) is a 1,3-benzodiazepine antidepressant, developed by Hoerscht in the early 1980s. In mouse tests, dazepinil inhibited tetrabenazine-induced ptosis and potentiated yohimbine toxicity. In vitro, dazepinil inhibited norepinephrine and serotonin uptake into rat brain synaptosomes and lacked anticholinergic activity.

Originator

Approval Year

PubMed

Substance Class Chemical
Record UNII
730EPY2HSM
Record Status Validated (UNII)
Record Version