HEPZIDINE

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National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C21H25NO
Molecular Weight	307.4293
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of HEPZIDINE

Structure Search

SMILES

CN1CCC(CC1)OC2C3=CC=CC=C3CCC4=CC=CC=C24

InChI

InChIKey=MNIZCABHARMLFF-UHFFFAOYSA-N

InChI=1S/C21H25NO/c1-22-14-12-18(13-15-22)23-21-19-8-4-2-6-16(19)10-11-17-7-3-5-9-20(17)21/h2-9,18,21H,10-15H2,1H3

HIDE SMILES / InChI

Molecular Formula	C21H25NO
Molecular Weight	307.4293
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/5649888

Hepzidine (BS 7051) is a compound, possessing antidepressive and anticholinergic properties.

CNS Activity

Approval Year

Conditions

Conditions

Condition	Modality	Targets	Highest Phase	Product
Depression 235 Sources: https://www.ncbi.nlm.nih.gov/pubmed/4964622	Primary		Not Provided 504	Unknown Approved Use Unknown

PubMed

PubMed

Title	Date	PubMed
NEW PSYCHOTROPIC AGENTS. V. DERIVATIVES OF 5-CYANO- AND 5-CARBOXAMIDODIBENZO(A,D)CYCLOHEPTADIENE.	1963 May	14185978
[On the antidepressive and anticholenergic action of hepzidine malate].	1967 May 29	4964622
Investigations into the metabolic fate and distribution of hepzidine maleate in the rat and the mouse.	1968 May	5649888

Sample Use Guides

In Vivo Use Guide

in rat: 10 mg/kg

Route of Administration: Oral

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:29:17 GMT 2023` Edited by `admin` on `Fri Dec 15 15:29:17 GMT 2023`
Record UNII	72FH6333M6
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

HEPZIDINE

Official Name

English

hepzidine [INN]

Common Name

English

4-(10,11-DIHYDRO-5H-DIBENZO(A,D)CYCLOHEPTEN-5-YLOXY)-1-METHYLPIPERIDINE

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C265

Created by admin on Fri Dec 15 15:29:17 GMT 2023 , Edited by admin on Fri Dec 15 15:29:17 GMT 2023

Code System Code Type Description

FDA UNII

72FH6333M6

Created by admin on Fri Dec 15 15:29:17 GMT 2023 , Edited by admin on Fri Dec 15 15:29:17 GMT 2023

PRIMARY

ChEMBL

CHEMBL522580

Created by admin on Fri Dec 15 15:29:17 GMT 2023 , Edited by admin on Fri Dec 15 15:29:17 GMT 2023

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PUBCHEM

70593

Created by admin on Fri Dec 15 15:29:17 GMT 2023 , Edited by admin on Fri Dec 15 15:29:17 GMT 2023

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CAS

1096-72-6

Created by admin on Fri Dec 15 15:29:17 GMT 2023 , Edited by admin on Fri Dec 15 15:29:17 GMT 2023

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WIKIPEDIA

HEPZIDINE

Created by admin on Fri Dec 15 15:29:17 GMT 2023 , Edited by admin on Fri Dec 15 15:29:17 GMT 2023

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SMS_ID

100000083931

Created by admin on Fri Dec 15 15:29:17 GMT 2023 , Edited by admin on Fri Dec 15 15:29:17 GMT 2023

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EVMPD

SUB08019MIG

Created by admin on Fri Dec 15 15:29:17 GMT 2023 , Edited by admin on Fri Dec 15 15:29:17 GMT 2023

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NCI_THESAURUS

C65844

Created by admin on Fri Dec 15 15:29:17 GMT 2023 , Edited by admin on Fri Dec 15 15:29:17 GMT 2023

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EPA CompTox

DTXSID20883195

Created by admin on Fri Dec 15 15:29:17 GMT 2023 , Edited by admin on Fri Dec 15 15:29:17 GMT 2023

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INN

1754

Created by admin on Fri Dec 15 15:29:17 GMT 2023 , Edited by admin on Fri Dec 15 15:29:17 GMT 2023

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Related Record Type Details


					72FH6333M6

HEPZIDINE

ACTIVE MOIETY