Hepzidine maleate

Details

Stereochemistry	ACHIRAL
Molecular Formula	C21H25NO.C4H4O4
Molecular Weight	423.5015
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

OC(=O)\C=C/C(O)=O.CN1CCC(CC1)OC2C3=CC=CC=C3CCC4=CC=CC=C24

InChI

InChIKey=QIFFMXMEBPAKMS-BTJKTKAUSA-N

InChI=1S/C21H25NO.C4H4O4/c1-22-14-12-18(13-15-22)23-21-19-8-4-2-6-16(19)10-11-17-7-3-5-9-20(17)21;5-3(6)1-2-4(7)8/h2-9,18,21H,10-15H2,1H3;1-2H,(H,5,6)(H,7,8)/b;2-1-

HIDE SMILES / InChI

Molecular Formula	C21H25NO
Molecular Weight	307.4293
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C4H4O4
Molecular Weight	116.0722
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	1
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/5649888

Hepzidine (BS 7051) is a compound, possessing antidepressive and anticholinergic properties.

CNS Activity

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Depression 240 Sources: https://www.ncbi.nlm.nih.gov/pubmed/4964622	Primary		Not Provided 511	Unknown Approved Use Unknown

PubMed

Title	Date	PubMed
Investigations into the metabolic fate and distribution of hepzidine maleate in the rat and the mouse.	1968-05	5649888
[On the antidepressive and anticholenergic action of hepzidine malate].	1967-05-29	4964622
NEW PSYCHOTROPIC AGENTS. V. DERIVATIVES OF 5-CYANO- AND 5-CARBOXAMIDODIBENZO(A,D)CYCLOHEPTADIENE.	1963-05	14185978

Sample Use Guides

In Vivo Use Guide

in rat: 10 mg/kg

Route of Administration: Oral

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Mon Mar 31 22:11:48 GMT 2025` Edited by `admin` on `Mon Mar 31 22:11:48 GMT 2025`
Record UNII	55F8T2B2CH
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Hepzidine maleate

Common Name

English

NSC-169430

Preferred Name

English

4-[(10,11-Dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)oxy]-1-methylpiperidide hydrogen maleate

Systematic Name

English

Piperidine, 4-[(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)oxy]-1-methyl-, (Z)-2-butenedioate (1:1)

Systematic Name

English

BS-7051

Code

English

Code System Code Type Description

CAS

1057-81-4