U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ABSOLUTE
Molecular Formula C16H17N3O7S2
Molecular Weight 427.452
Optical Activity UNSPECIFIED
Defined Stereocenters 2 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of CEFOXITIN

SMILES

[H][C@]12SCC(COC(N)=O)=C(N1C(=O)[C@]2(NC(=O)CC3=CC=CS3)OC)C(O)=O

InChI

InChIKey=WZOZEZRFJCJXNZ-ZBFHGGJFSA-N
InChI=1S/C16H17N3O7S2/c1-25-16(18-10(20)5-9-3-2-4-27-9)13(23)19-11(12(21)22)8(6-26-15(17)24)7-28-14(16)19/h2-4,14H,5-7H2,1H3,(H2,17,24)(H,18,20)(H,21,22)/t14-,16+/m1/s1

HIDE SMILES / InChI

Molecular Formula C16H17N3O7S2
Molecular Weight 427.452
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 2 / 2
E/Z Centers 0
Optical Activity UNSPECIFIED

Description
Curator's Comment: Description was created based on several sources, including https://www.drugs.com/pro/cefoxitin.html

Cefoxitin is a cephamycin antibiotic often grouped with the second-generation cephalosporins. It is active against a broad range of gram-negative bacteria including anaerobes. The methoxy group in the 7a position provides cefoxitin with a high degree of stability in the presence of beta-lactamases, both penicillinases and cephalosporinases, of gram-negative bacteria. The bactericidal action of cefoxitin results from inhibition of cell wall synthesis.

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
Target ID: Klebsiella pneumoniae growth
Target ID: P08506
Gene ID: 945455.0
Gene Symbol: dacC
Target Organism: Escherichia coli (strain K12)
Target ID: P0AEB2
Gene ID: 945222.0
Gene Symbol: dacA
Target Organism: Escherichia coli (strain K12)
Target ID: P0AFI5
Gene ID: 946662.0
Gene Symbol: pbpG
Target Organism: Escherichia coli (strain K12)
Target ID: P02919
Gene ID: 944843.0
Gene Symbol: mrcB
Target Organism: Escherichia coli (strain K12)
Target ID: P0A3M6
Gene ID: 933948.0
Gene Symbol: penA
Target Organism: Streptococcus pneumoniae (strain ATCC BAA-255 / R6)
8.0 nM [IC50]
Target ID: Q8DR59
Gene ID: 934791.0
Gene Symbol: pbpA
Target Organism: Streptococcus pneumoniae (strain ATCC BAA-255 / R6)
6.8 nM [IC50]
Target ID: 933569.0
Gene Symbol: pbp2a
2.4 nM [IC50]
Target ID: 934893.0
Gene Symbol: pbp1b
0.145 nM [IC50]
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Curative
Cefoxitin

Approved Use

Cefoxitin for Injection, USP is indicated for the treatment of serious infections caused by susceptible strains of the designated microorganisms in the diseases listed below. (1) Lower respiratory tract infections, including pneumonia and lung abscess, caused by Streptococcus pneumoniae, other streptococci (excluding enterococci, e.g., Enterococcus faecalis [formerly Streptococcus faecalis]), Staphylococcus aureus (including penicillinase-producing strains), Escherichia coli, Klebsiella species, Haemophilus influenzae, and Bacteroides species. (2) Urinary tract infections caused by Escherichia coli, Klebsiella species, Proteus mirabilis, Morganella morganii, Proteus vulgaris and Providencia species (including P. rettgeri). (3) Intra-abdominal infections, including peritonitis and intra-abdominal abscess, caused by Escherichia coli, Klebsiella species, Bacteroides species including Bacteroides fragilis, and Clostridium species. (4) Gynecological infections, including endometritis, pelvic cellulitis, and pelvic inflammatory disease caused by Escherichia coli, Neisseria gonorrhoeae (including penicillinase-producing strains), Bacteroides species including B. fragilis, Clostridium species, Peptococcus niger, Peptostreptococcus species and Streptococcus agalactiae. Cefoxitin for injection, like cephalosporins, has no activity against Chlamydia trachomatis. Therefore, when Cefoxitin for injection is used in the treatment of patients with pelvic inflammatory disease and C. trachomatis is one of the suspected pathogens, appropriate anti-chlamydial coverage should be added. (5) Septicemia caused by Streptococcus pneumoniae, Staphylococcus aureus (including penicillinase-producing strains), Escherichia coli, Klebsiella species, and Bacteroides species including B. fragilis. (6) Bone and joint infections caused by Staphylococcus aureus (including penicillinase-producing strains). (7) Skin and skin structure infections caused by Staphylococcus aureus (including penicillinase-producing strains), Staphylococcus epidermidis, Streptococcus pyogenes and other streptococci (excluding enterococci e.g., Enterococcus faecalis [formerly Streptococcus faecalis]), Escherichia coli, Proteus mirabilis, Klebsiella species, Bacteroides species including B. fragilis, Clostridium species, Peptococcus niger, and Peptostreptococcus species.

Launch Date

2010
Curative
Cefoxitin

Approved Use

Cefoxitin for Injection, USP is indicated for the treatment of serious infections caused by susceptible strains of the designated microorganisms in the diseases listed below. (1) Lower respiratory tract infections, including pneumonia and lung abscess, caused by Streptococcus pneumoniae, other streptococci (excluding enterococci, e.g., Enterococcus faecalis [formerly Streptococcus faecalis]), Staphylococcus aureus (including penicillinase-producing strains), Escherichia coli, Klebsiella species, Haemophilus influenzae, and Bacteroides species. (2) Urinary tract infections caused by Escherichia coli, Klebsiella species, Proteus mirabilis, Morganella morganii, Proteus vulgaris and Providencia species (including P. rettgeri). (3) Intra-abdominal infections, including peritonitis and intra-abdominal abscess, caused by Escherichia coli, Klebsiella species, Bacteroides species including Bacteroides fragilis, and Clostridium species. (4) Gynecological infections, including endometritis, pelvic cellulitis, and pelvic inflammatory disease caused by Escherichia coli, Neisseria gonorrhoeae (including penicillinase-producing strains), Bacteroides species including B. fragilis, Clostridium species, Peptococcus niger, Peptostreptococcus species and Streptococcus agalactiae. Cefoxitin for injection, like cephalosporins, has no activity against Chlamydia trachomatis. Therefore, when Cefoxitin for injection is used in the treatment of patients with pelvic inflammatory disease and C. trachomatis is one of the suspected pathogens, appropriate anti-chlamydial coverage should be added. (5) Septicemia caused by Streptococcus pneumoniae, Staphylococcus aureus (including penicillinase-producing strains), Escherichia coli, Klebsiella species, and Bacteroides species including B. fragilis. (6) Bone and joint infections caused by Staphylococcus aureus (including penicillinase-producing strains). (7) Skin and skin structure infections caused by Staphylococcus aureus (including penicillinase-producing strains), Staphylococcus epidermidis, Streptococcus pyogenes and other streptococci (excluding enterococci e.g., Enterococcus faecalis [formerly Streptococcus faecalis]), Escherichia coli, Proteus mirabilis, Klebsiella species, Bacteroides species including B. fragilis, Clostridium species, Peptococcus niger, and Peptostreptococcus species.

Launch Date

2010
Curative
Cefoxitin

Approved Use

Cefoxitin for Injection, USP is indicated for the treatment of serious infections caused by susceptible strains of the designated microorganisms in the diseases listed below. (1) Lower respiratory tract infections, including pneumonia and lung abscess, caused by Streptococcus pneumoniae, other streptococci (excluding enterococci, e.g., Enterococcus faecalis [formerly Streptococcus faecalis]), Staphylococcus aureus (including penicillinase-producing strains), Escherichia coli, Klebsiella species, Haemophilus influenzae, and Bacteroides species. (2) Urinary tract infections caused by Escherichia coli, Klebsiella species, Proteus mirabilis, Morganella morganii, Proteus vulgaris and Providencia species (including P. rettgeri). (3) Intra-abdominal infections, including peritonitis and intra-abdominal abscess, caused by Escherichia coli, Klebsiella species, Bacteroides species including Bacteroides fragilis, and Clostridium species. (4) Gynecological infections, including endometritis, pelvic cellulitis, and pelvic inflammatory disease caused by Escherichia coli, Neisseria gonorrhoeae (including penicillinase-producing strains), Bacteroides species including B. fragilis, Clostridium species, Peptococcus niger, Peptostreptococcus species and Streptococcus agalactiae. Cefoxitin for injection, like cephalosporins, has no activity against Chlamydia trachomatis. Therefore, when Cefoxitin for injection is used in the treatment of patients with pelvic inflammatory disease and C. trachomatis is one of the suspected pathogens, appropriate anti-chlamydial coverage should be added. (5) Septicemia caused by Streptococcus pneumoniae, Staphylococcus aureus (including penicillinase-producing strains), Escherichia coli, Klebsiella species, and Bacteroides species including B. fragilis. (6) Bone and joint infections caused by Staphylococcus aureus (including penicillinase-producing strains). (7) Skin and skin structure infections caused by Staphylococcus aureus (including penicillinase-producing strains), Staphylococcus epidermidis, Streptococcus pyogenes and other streptococci (excluding enterococci e.g., Enterococcus faecalis [formerly Streptococcus faecalis]), Escherichia coli, Proteus mirabilis, Klebsiella species, Bacteroides species including B. fragilis, Clostridium species, Peptococcus niger, and Peptostreptococcus species.

Launch Date

2010
Cmax

Cmax

ValueDoseCo-administeredAnalytePopulation
24 μg/mL
1 g single, intramuscular
dose: 1 g
route of administration: Intramuscular
experiment type: SINGLE
co-administered:
CEFOXITIN plasma
Homo sapiens
population: UNKNOWN
age: ADULT
sex: UNKNOWN
food status: UNKNOWN
AUC

AUC

ValueDoseCo-administeredAnalytePopulation
33.5 μg × h/mL
1 g single, intramuscular
dose: 1 g
route of administration: Intramuscular
experiment type: SINGLE
co-administered:
CEFOXITIN plasma
Homo sapiens
population: UNKNOWN
age: ADULT
sex: UNKNOWN
food status: UNKNOWN
T1/2

T1/2

ValueDoseCo-administeredAnalytePopulation
0.67 h
1 g single, intramuscular
dose: 1 g
route of administration: Intramuscular
experiment type: SINGLE
co-administered:
CEFOXITIN plasma
Homo sapiens
population: UNKNOWN
age: ADULT
sex: UNKNOWN
food status: UNKNOWN
Funbound

Funbound

ValueDoseCo-administeredAnalytePopulation
27%
1 g single, intramuscular
dose: 1 g
route of administration: Intramuscular
experiment type: SINGLE
co-administered:
CEFOXITIN plasma
Homo sapiens
population: UNKNOWN
age: ADULT
sex: UNKNOWN
food status: UNKNOWN
Doses

Doses

DosePopulationAdverse events​
2 g single, intramuscular
Dose: 2 g
Route: intramuscular
Route: single
Dose: 2 g
Sources:
unhealthy, 17 years
n = 1
Health Status: unhealthy
Age Group: 17 years
Sex: F
Population Size: 1
Sources:
Disc. AE: Hoigne's syndrome...
AEs leading to
discontinuation/dose reduction:
Hoigne's syndrome (1 patient)
Sources:
12 g 1 times / day multiple, intravenous
Highest studied dose
Dose: 12 g, 1 times / day
Route: intravenous
Route: multiple
Dose: 12 g, 1 times / day
Sources:
unhealthy, 22 years
n = 1
Health Status: unhealthy
Condition: bacterial endocarditis
Age Group: 22 years
Sex: M
Population Size: 1
Sources:
2 g 3 times / day multiple, intravenous
Dose: 2 g, 3 times / day
Route: intravenous
Route: multiple
Dose: 2 g, 3 times / day
Sources:
unhealthy, 45 years
n = 1
Health Status: unhealthy
Age Group: 45 years
Sex: F
Population Size: 1
Sources:
Disc. AE: Hemolytic anemia...
AEs leading to
discontinuation/dose reduction:
Hemolytic anemia (1 patient)
Sources:
1 g 4 times / day multiple, intravenous
Dose: 1 g, 4 times / day
Route: intravenous
Route: multiple
Dose: 1 g, 4 times / day
Sources:
unhealthy, 77 years
n = 1
Health Status: unhealthy
Condition: peritonitis
Age Group: 77 years
Sex: M
Population Size: 1
Sources:
Disc. AE: Hemolytic anemia, Pancytopenia...
AEs leading to
discontinuation/dose reduction:
Hemolytic anemia (1 patient)
Pancytopenia (1 patient)
Sources:
AEs

AEs

AESignificanceDosePopulation
Hoigne's syndrome 1 patient
Disc. AE
2 g single, intramuscular
Dose: 2 g
Route: intramuscular
Route: single
Dose: 2 g
Sources:
unhealthy, 17 years
n = 1
Health Status: unhealthy
Age Group: 17 years
Sex: F
Population Size: 1
Sources:
Hemolytic anemia 1 patient
Disc. AE
2 g 3 times / day multiple, intravenous
Dose: 2 g, 3 times / day
Route: intravenous
Route: multiple
Dose: 2 g, 3 times / day
Sources:
unhealthy, 45 years
n = 1
Health Status: unhealthy
Age Group: 45 years
Sex: F
Population Size: 1
Sources:
Hemolytic anemia 1 patient
Disc. AE
1 g 4 times / day multiple, intravenous
Dose: 1 g, 4 times / day
Route: intravenous
Route: multiple
Dose: 1 g, 4 times / day
Sources:
unhealthy, 77 years
n = 1
Health Status: unhealthy
Condition: peritonitis
Age Group: 77 years
Sex: M
Population Size: 1
Sources:
Pancytopenia 1 patient
Disc. AE
1 g 4 times / day multiple, intravenous
Dose: 1 g, 4 times / day
Route: intravenous
Route: multiple
Dose: 1 g, 4 times / day
Sources:
unhealthy, 77 years
n = 1
Health Status: unhealthy
Condition: peritonitis
Age Group: 77 years
Sex: M
Population Size: 1
Sources:
PubMed

PubMed

TitleDatePubMed
Occurrence and transferability of beta-lactam resistance in Enterobacteriaceae isolated in Children's University Hospital in Bratislava.
2001
[Occurrence of beta-lactamase type ESBL and IBL in Pseudomonas aeruginosa rods].
2001
Prevalence and analysis of risk factors for infections caused by resistant Escherichia coli strains in Anhui, China.
2001 Aug
Antimicrobial resistance of strains of the Bacteroides fragilis group isolated from the intestinal tract of children and adults in Brazil.
2001 Aug
Natural antibiotic susceptibility of strains of the Enterobacter cloacae complex.
2001 Dec
A novel metallo-beta-lactamase, Mbl1b, produced by the environmental bacterium Caulobacter crescentus.
2001 Dec 14
Laparoscopic management of gallstone ileus.
2001 Jul-Sep
Cephalosporins in surgical prophylaxis.
2001 Nov
Influence of in-vivo endotoxin liberation on anti-anaerobic antimicrobial efficacy.
2001 Oct
[A study on beta-lactamase activity of biofilm Escherichia coli].
2001 Sep
CMY-2-producing Salmonella enterica, Klebsiella pneumoniae, Klebsiella oxytoca, Proteus mirabilis and Escherichia coli strains isolated in Spain (October 1999-December 2000).
2001 Sep
Molecular mechanisms of cefoxitin resistance in Escherichia coli from the Toronto area hospitals.
2001 Sep-Oct
Probing substrate binding to metallo-beta-lactamase L1 from Stenotrophomonas maltophilia by using site-directed mutagenesis.
2002
A luminescent Escherichia coli biosensor for the high throughput detection of beta-lactams.
2002 Apr
Cross-reactivity of cefotetan and ceftriaxone antibodies, associated with hemolytic anemia, with other: cephalosporins and penicillin.
2002 Aug
Mycobacterium fortuitum complex endocarditis-case report and literature review.
2002 Feb
[Identification of plasmid-encoded cephalosporinase ACC-1 among various enterobacteria (Klebsiella pneumoniae, Proteus mirabilis, Salmonella) isolated from a Tunisian hospital (Sfax 997-2000)].
2002 Feb
Multicentre evaluation of the VITEK 2 Advanced Expert System for interpretive reading of antimicrobial resistance tests.
2002 Feb
Characterization of blaCMY-11, an AmpC-type plasmid-mediated beta-lactamase gene in a Korean clinical isolate of Escherichia coli.
2002 Feb
Crystal structures of the Bacillus licheniformis BS3 class A beta-lactamase and of the acyl-enzyme adduct formed with cefoxitin.
2002 Feb 12
[Multidrug resistance in Klebsiella pneumoniae: multicenter study].
2002 Jan
Surgical prophylaxis in practice.
2002 Jan
Natural antibiotic susceptibility and biochemical profiles of Yersinia enterocolitica-like strains: Y. bercovieri, Y. mollaretii, Y. aldovae and 'Y. ruckeri'.
2002 Jan
Primary liver abscess caused by one clone of Klebsiella pneumoniae with two colonial morphotypes and resistotypes.
2002 Jan
Occurrence and characterization of resistance to extended-spectrum cephalosporins mediated by beta-lactamase CMY-2 in Salmonella isolated from food-producing animals in Canada.
2002 Jul
Comparison of several methods used for the determination of cephalosporins. Analysis of cephalexin in pharmaceutical samples.
2002 Jul 1
Characterization of cefotaxime-resistant Escherichia coli isolates from a nosocomial outbreak at three geriatric hospitals.
2002 Jun
Outbreak of multidrug-resistant Salmonella newport--United States, January-April 2002.
2002 Jun 28
Escherichia coli isolated from seafood: toxicity and plasmid profiles.
2002 Mar
A pathway-specific cell based screening system to detect bacterial cell wall inhibitors.
2002 Mar
The ACT-1 plasmid-encoded AmpC beta-lactamase is inducible: detection in a complex beta-lactamase background.
2002 Mar
[Genotypic exploration of a hospital neonatal outbreak due to Klebsiella pneumoniae producing extended-spectrum-betalactamase].
2002 May
Proposed protocol to reduce bacterial infectious complications in living related small bowel transplant recipients.
2002 May
Effectiveness of inpatient and outpatient treatment strategies for women with pelvic inflammatory disease: results from the Pelvic Inflammatory Disease Evaluation and Clinical Health (PEACH) Randomized Trial.
2002 May
Cefepime MIC as a predictor of the extended-spectrum beta-lactamase type in Klebsiella pneumoniae, Taiwan.
2002 May
Rapidly growing members of the genus Mycobacterium affecting dogs and cats.
2002 May-Jun
Comparative in vitro activities of ertapenem against bacterial pathogens from patients with acute pelvic infection.
2002 Nov
Epidemiological and antibiotic resistant study on extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae in Zhejiang Province.
2002 Oct
Natural antibiotic susceptibility of Enterobacter spp., with special reference to Enterobacter aerogenes and Enterobacter intermedius strains.
2002 Oct
Molecular epidemiology of a citywide outbreak of extended-spectrum beta-lactamase-producing Klebsiella pneumoniae infection.
2002 Oct 1
Klebsiella and enterobacter: antibiotic resistance and treatment implications.
2002 Sep
Biochemical characterization of a novel extended-spectrum beta-lactamase from Pseudomonas aeruginosa 802.
2002 Spring
Automated ribotyping and pulsed-field gel electrophoresis for rapid identification of multidrug-resistant Salmonella serotype newport.
2003 Apr
Natural antimicrobial susceptibilities of strains of 'unusual' Serratia species: S. ficaria, S. fonticola, S. odorifera, S. plymuthica and S. rubidaea.
2003 Apr
Pelvic inflammatory disease: how should it be managed?
2003 Feb
Multiple antibiotic-resistance mechanisms including a novel combination of extended-spectrum beta-lactamases in a Klebsiella pneumoniae clinical strain isolated in Argentina.
2003 Jul
Group 1 beta-lactamases of Aeromonas caviae and their resistance to beta-lactam antibiotics.
2003 Mar
A seven-year survey of Klebsiella pneumoniae producing TEM-24 extended-spectrum beta-lactamase in Nice University Hospital (1994-2000).
2003 May
Sequence analysis and biochemical characterisation of chromosomal CAV-1 (Aeromonas caviae), the parental cephalosporinase of plasmid-mediated AmpC 'FOX' cluster.
2003 May 16
Beta-lactamase characterization in Escherichia coli isolates with diminished susceptibility or resistance to extended-spectrum cephalosporins recovered from sick animals in Spain.
2003 Summer
Patents

Sample Use Guides

In Vivo Use Guide
Adults The usual adult dosage range is 1 gram to 2 grams every six to eight hours.
Route of Administration: Intravenous
CEFOXITIN inhibited Mycobacterium fortuitum growth with MIC 32 ug/ml
Substance Class Chemical
Created
by admin
on Sat Dec 16 17:08:34 GMT 2023
Edited
by admin
on Sat Dec 16 17:08:34 GMT 2023
Record UNII
6OEV9DX57Y
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
CEFOXITIN
INN   MI   ORANGE BOOK   USAN   USP-RS   VANDF   WHO-DD  
INN   USAN  
Official Name English
J01DC01
Code English
(6R,7S)-3-(Hydroxymethyl)-7-methoxy-8-oxo-7-[2-(2-thienyl)acetamido]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid carbamate (ester)
Systematic Name English
CEFOXITIN [USAN]
Common Name English
Cefoxitin [WHO-DD]
Common Name English
CEFOXITIN [VANDF]
Common Name English
CEFOXITIN [USP-RS]
Common Name English
CEFOXITIN [ORANGE BOOK]
Common Name English
CEFOXITIN [MI]
Common Name English
cefoxitin [INN]
Common Name English
Classification Tree Code System Code
NDF-RT N0000011161
Created by admin on Sat Dec 16 17:08:35 GMT 2023 , Edited by admin on Sat Dec 16 17:08:35 GMT 2023
NDF-RT N0000011161
Created by admin on Sat Dec 16 17:08:35 GMT 2023 , Edited by admin on Sat Dec 16 17:08:35 GMT 2023
NDF-RT N0000011161
Created by admin on Sat Dec 16 17:08:35 GMT 2023 , Edited by admin on Sat Dec 16 17:08:35 GMT 2023
NDF-RT N0000011161
Created by admin on Sat Dec 16 17:08:35 GMT 2023 , Edited by admin on Sat Dec 16 17:08:35 GMT 2023
LIVERTOX NBK548666
Created by admin on Sat Dec 16 17:08:35 GMT 2023 , Edited by admin on Sat Dec 16 17:08:35 GMT 2023
NDF-RT N0000011161
Created by admin on Sat Dec 16 17:08:35 GMT 2023 , Edited by admin on Sat Dec 16 17:08:35 GMT 2023
NDF-RT N0000011161
Created by admin on Sat Dec 16 17:08:35 GMT 2023 , Edited by admin on Sat Dec 16 17:08:35 GMT 2023
WHO-VATC QJ01DC01
Created by admin on Sat Dec 16 17:08:35 GMT 2023 , Edited by admin on Sat Dec 16 17:08:35 GMT 2023
NDF-RT N0000011161
Created by admin on Sat Dec 16 17:08:35 GMT 2023 , Edited by admin on Sat Dec 16 17:08:35 GMT 2023
NDF-RT N0000175488
Created by admin on Sat Dec 16 17:08:35 GMT 2023 , Edited by admin on Sat Dec 16 17:08:35 GMT 2023
NDF-RT N0000011161
Created by admin on Sat Dec 16 17:08:35 GMT 2023 , Edited by admin on Sat Dec 16 17:08:35 GMT 2023
NDF-RT N0000011161
Created by admin on Sat Dec 16 17:08:35 GMT 2023 , Edited by admin on Sat Dec 16 17:08:35 GMT 2023
NCI_THESAURUS C357
Created by admin on Sat Dec 16 17:08:35 GMT 2023 , Edited by admin on Sat Dec 16 17:08:35 GMT 2023
NDF-RT N0000011161
Created by admin on Sat Dec 16 17:08:35 GMT 2023 , Edited by admin on Sat Dec 16 17:08:35 GMT 2023
LIVERTOX NBK547862
Created by admin on Sat Dec 16 17:08:35 GMT 2023 , Edited by admin on Sat Dec 16 17:08:35 GMT 2023
NDF-RT N0000011161
Created by admin on Sat Dec 16 17:08:35 GMT 2023 , Edited by admin on Sat Dec 16 17:08:35 GMT 2023
NDF-RT N0000011161
Created by admin on Sat Dec 16 17:08:35 GMT 2023 , Edited by admin on Sat Dec 16 17:08:35 GMT 2023
WHO-ATC J01DC01
Created by admin on Sat Dec 16 17:08:35 GMT 2023 , Edited by admin on Sat Dec 16 17:08:35 GMT 2023
Code System Code Type Description
ChEMBL
CHEMBL996
Created by admin on Sat Dec 16 17:08:35 GMT 2023 , Edited by admin on Sat Dec 16 17:08:35 GMT 2023
PRIMARY
MERCK INDEX
m3208
Created by admin on Sat Dec 16 17:08:35 GMT 2023 , Edited by admin on Sat Dec 16 17:08:35 GMT 2023
PRIMARY Merck Index
DRUG CENTRAL
550
Created by admin on Sat Dec 16 17:08:35 GMT 2023 , Edited by admin on Sat Dec 16 17:08:35 GMT 2023
PRIMARY
RS_ITEM_NUM
1098107
Created by admin on Sat Dec 16 17:08:35 GMT 2023 , Edited by admin on Sat Dec 16 17:08:35 GMT 2023
PRIMARY
ECHA (EC/EINECS)
252-641-2
Created by admin on Sat Dec 16 17:08:35 GMT 2023 , Edited by admin on Sat Dec 16 17:08:35 GMT 2023
PRIMARY
CAS
35607-66-0
Created by admin on Sat Dec 16 17:08:35 GMT 2023 , Edited by admin on Sat Dec 16 17:08:35 GMT 2023
PRIMARY
DAILYMED
6OEV9DX57Y
Created by admin on Sat Dec 16 17:08:35 GMT 2023 , Edited by admin on Sat Dec 16 17:08:35 GMT 2023
PRIMARY
WIKIPEDIA
CEFOXITIN
Created by admin on Sat Dec 16 17:08:35 GMT 2023 , Edited by admin on Sat Dec 16 17:08:35 GMT 2023
PRIMARY
LACTMED
Cefoxitin
Created by admin on Sat Dec 16 17:08:35 GMT 2023 , Edited by admin on Sat Dec 16 17:08:35 GMT 2023
PRIMARY
INN
3397
Created by admin on Sat Dec 16 17:08:35 GMT 2023 , Edited by admin on Sat Dec 16 17:08:35 GMT 2023
PRIMARY
EVMPD
SUB07409MIG
Created by admin on Sat Dec 16 17:08:35 GMT 2023 , Edited by admin on Sat Dec 16 17:08:35 GMT 2023
PRIMARY
CHEBI
209807
Created by admin on Sat Dec 16 17:08:35 GMT 2023 , Edited by admin on Sat Dec 16 17:08:35 GMT 2023
PRIMARY
MESH
D002440
Created by admin on Sat Dec 16 17:08:35 GMT 2023 , Edited by admin on Sat Dec 16 17:08:35 GMT 2023
PRIMARY
RXCUI
2189
Created by admin on Sat Dec 16 17:08:35 GMT 2023 , Edited by admin on Sat Dec 16 17:08:35 GMT 2023
PRIMARY RxNorm
FDA UNII
6OEV9DX57Y
Created by admin on Sat Dec 16 17:08:35 GMT 2023 , Edited by admin on Sat Dec 16 17:08:35 GMT 2023
PRIMARY
SMS_ID
100000081807
Created by admin on Sat Dec 16 17:08:35 GMT 2023 , Edited by admin on Sat Dec 16 17:08:35 GMT 2023
PRIMARY
DRUG BANK
DB01331
Created by admin on Sat Dec 16 17:08:35 GMT 2023 , Edited by admin on Sat Dec 16 17:08:35 GMT 2023
PRIMARY
NCI_THESAURUS
C61665
Created by admin on Sat Dec 16 17:08:35 GMT 2023 , Edited by admin on Sat Dec 16 17:08:35 GMT 2023
PRIMARY
EPA CompTox
DTXSID1022764
Created by admin on Sat Dec 16 17:08:35 GMT 2023 , Edited by admin on Sat Dec 16 17:08:35 GMT 2023
PRIMARY
PUBCHEM
441199
Created by admin on Sat Dec 16 17:08:35 GMT 2023 , Edited by admin on Sat Dec 16 17:08:35 GMT 2023
PRIMARY
Related Record Type Details
SALT/SOLVATE -> PARENT
BINDER->LIGAND
BINDING
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ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
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