Cenvacibart

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 21:17:24 GMT 2025` Edited by `admin` on `Wed Apr 02 21:17:24 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG4\|KAPPA
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	6NM5PD4YTH
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Cenvacibart

Official Name

English

REGN-7508

Preferred Name

English

cenvacibart [INN]

Common Name

English

immunoglobulin G4-kappa, anti-[Homo sapiens F11 (coagulation factor 11, coagulation factor XI, FXI, plasma thromboplastin antecedent, PTA)], Homo sapiens monoclonal antibody

Common Name

English

Immunoglobulin G4 [226-proline], anti-(human blood-coagulation factor XI/XIa) (human monoclonal REGN7508 ?4-chain), disulfide with human monoclonal REGN7508 ?-chain, dimer

Common Name

English

H-gamma4 heavy chain Homo sapiens (1-445) [VH (Homo sapiens IGHV3-11*01 (91.7%) -(IGHD) -IGHJ3*02 (100%), CDR-IMGT [8.8.11] (26-33.51-58.97-107)) (1-118) -Homo sapiens IGHG4*01, nG4m(a) CH2 L92, 12-G4v5 h P10(CH1 (119-216), hinge 1-12 S10>P (226) (217-22

Common Name

English

Code System Code Type Description

CAS

3008610-21-4

Created by admin on Wed Apr 02 21:17:24 GMT 2025 , Edited by admin on Wed Apr 02 21:17:24 GMT 2025

PRIMARY

INN

13411

Created by admin on Wed Apr 02 21:17:24 GMT 2025 , Edited by admin on Wed Apr 02 21:17:24 GMT 2025

PRIMARY

FDA UNII

6NM5PD4YTH

Created by admin on Wed Apr 02 21:17:24 GMT 2025 , Edited by admin on Wed Apr 02 21:17:24 GMT 2025

PRIMARY

From	To
1_22	1_96
2_22	2_96
2_132	4_214
2_145	2_201
2_259	2_319
1_132	3_214
2_365	2_423
3_23	3_88
3_134	3_194
4_23	4_88
4_134	4_194
1_145	1_201
1_224	2_224
1_227	2_227
1_259	1_319
1_365	1_423