U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C21H26N2O
Molecular Weight 322.4439
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ACETYLFENTANYL

SMILES

CC(=O)N(C1CCN(CCC2=CC=CC=C2)CC1)C3=CC=CC=C3

InChI

InChIKey=FYIUUQUPOKIKNI-UHFFFAOYSA-N
InChI=1S/C21H26N2O/c1-18(24)23(20-10-6-3-7-11-20)21-13-16-22(17-14-21)15-12-19-8-4-2-5-9-19/h2-11,21H,12-17H2,1H3

HIDE SMILES / InChI

Molecular Formula C21H26N2O
Molecular Weight 322.4439
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
Substance Class Chemical
Created
by admin
on Thu Jul 06 11:11:00 UTC 2023
Edited
by admin
on Thu Jul 06 11:11:00 UTC 2023
Record UNII
6DZ28538KS
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ACETYLFENTANYL
Common Name English
ACETYL FENTANYL
Common Name English
FENTANYL CITRATE IMPURITY C [EP IMPURITY]
Common Name English
ACETAMIDE, N-PHENYL-N-(1-(2-PHENYLETHYL)-4-PIPERIDINYL)-
Systematic Name English
PIPERIDINE, 1-PHENETHYL-4-(N-PHENYLACETAMIDO)-
Systematic Name English
FENTANYL RELATED COMPOUND G CI [USP-RS]
Common Name English
FENTANYL RELATED COMPOUND G [USP IMPURITY]
Common Name English
FENTANYL RELATED COMPOUND G CI
USP-RS  
Common Name English
J125.906G
Code English
FENTANYL IMPURITY C [EP IMPURITY]
Common Name English
N-(1-PHENETHYLPIPERIDIN-4-YL)-N-PHENYLACETAMIDE
Systematic Name English
N-PHENYL-N-(1-(2-PHENYLETHYL)PIPERIDIN-4-YL)ACETAMIDE
Systematic Name English
Classification Tree Code System Code
WIKIPEDIA Designer-drugs-Acetylfentanyl
Created by admin on Thu Jul 06 11:11:00 UTC 2023 , Edited by admin on Thu Jul 06 11:11:00 UTC 2023
DEA NO. 9821
Created by admin on Thu Jul 06 11:11:00 UTC 2023 , Edited by admin on Thu Jul 06 11:11:00 UTC 2023
WIKIPEDIA List_of_fentanyl_analogues
Created by admin on Thu Jul 06 11:11:00 UTC 2023 , Edited by admin on Thu Jul 06 11:11:00 UTC 2023
Code System Code Type Description
RS_ITEM_NUM
1269979
Created by admin on Thu Jul 06 11:11:00 UTC 2023 , Edited by admin on Thu Jul 06 11:11:00 UTC 2023
PRIMARY
WEB RESOURCE
ACETYLFENTANYL
Created by admin on Thu Jul 06 11:11:00 UTC 2023 , Edited by admin on Thu Jul 06 11:11:00 UTC 2023
PRIMARY
EPA CompTox
DTXSID80186275
Created by admin on Thu Jul 06 11:11:00 UTC 2023 , Edited by admin on Thu Jul 06 11:11:00 UTC 2023
PRIMARY
EVMPD
SUB180510
Created by admin on Thu Jul 06 11:11:00 UTC 2023 , Edited by admin on Thu Jul 06 11:11:00 UTC 2023
PRIMARY
FDA UNII
6DZ28538KS
Created by admin on Thu Jul 06 11:11:00 UTC 2023 , Edited by admin on Thu Jul 06 11:11:00 UTC 2023
PRIMARY
CAS
3258-84-2
Created by admin on Thu Jul 06 11:11:00 UTC 2023 , Edited by admin on Thu Jul 06 11:11:00 UTC 2023
PRIMARY
PUBCHEM
527015
Created by admin on Thu Jul 06 11:11:00 UTC 2023 , Edited by admin on Thu Jul 06 11:11:00 UTC 2023
PRIMARY
SMS_ID
100000166398
Created by admin on Thu Jul 06 11:11:00 UTC 2023 , Edited by admin on Thu Jul 06 11:11:00 UTC 2023
PRIMARY
WIKIPEDIA
ACETYLFENTANYL
Created by admin on Thu Jul 06 11:11:00 UTC 2023 , Edited by admin on Thu Jul 06 11:11:00 UTC 2023
PRIMARY Acetylfentanyl was discovered at the same time as fentanyl itself and had only rarely been encountered on the illicit market in the late 1980s. However, in 2013, Canadian police seized 3 kilograms of acetylfentanyl. As a μ-opioid receptor agonist, acetylfentanyl may serve as a direct substitute for heroin or other opioids. Side effects of fentanyl analogs are similar to those of fentanyl itself, which include itching, nausea and potentially serious respiratory depression, which can be life-threatening.
Related Record Type Details
SALT/SOLVATE -> PARENT
TARGET -> AGONIST
BINDING
Ki
Related Record Type Details
PARENT -> IMPURITY
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
PARENT -> IMPURITY
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
PARENT -> IMPURITY
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Related Record Type Details
ACTIVE MOIETY
ED50(mg/kg) = 0.021, LD50(mg/kg) = 9.3, Potency ratio to morphine = 15.7, Potency ratio to fentanyl = 0.29