ACETYLFENTANYL

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C21H26N2O
Molecular Weight	322.4439
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of ACETYLFENTANYL

Structure Search

SMILES

CC(=O)N(C1CCN(CCC2=CC=CC=C2)CC1)C3=CC=CC=C3

InChI

InChIKey=FYIUUQUPOKIKNI-UHFFFAOYSA-N

InChI=1S/C21H26N2O/c1-18(24)23(20-10-6-3-7-11-20)21-13-16-22(17-14-21)15-12-19-8-4-2-5-9-19/h2-11,21H,12-17H2,1H3

HIDE SMILES / InChI

Molecular Formula	C21H26N2O
Molecular Weight	322.4439
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Targets

Targets

Primary Target	Pharmacology	Condition	Potency
Mu opioid receptor 221 Target ID: CHEMBL233 Sources: https://www.ncbi.nlm.nih.gov/pubmed/30242482	Agonist 2678

Substance Class	Chemical Created by `admin` on `Sat Dec 16 05:26:06 UTC 2023` Edited by `admin` on `Sat Dec 16 05:26:06 UTC 2023`
Record UNII	6DZ28538KS
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

ACETYLFENTANYL

Common Name

English

ACETYL FENTANYL

Common Name

English

FENTANYL CITRATE IMPURITY C [EP IMPURITY]

Common Name

English

ACETAMIDE, N-PHENYL-N-(1-(2-PHENYLETHYL)-4-PIPERIDINYL)-

Systematic Name

English

PIPERIDINE, 1-PHENETHYL-4-(N-PHENYLACETAMIDO)-

Systematic Name

English

FENTANYL RELATED COMPOUND G CI [USP-RS]

Common Name

English

FENTANYL RELATED COMPOUND G [USP IMPURITY]

Common Name

English

FENTANYL RELATED COMPOUND G CI

Common Name

English

J125.906G

Code

English

FENTANYL IMPURITY C [EP IMPURITY]

Common Name

English

N-(1-PHENETHYLPIPERIDIN-4-YL)-N-PHENYLACETAMIDE

Systematic Name

English

N-PHENYL-N-(1-(2-PHENYLETHYL)PIPERIDIN-4-YL)ACETAMIDE

Systematic Name

English

Classification Tree Code System Code

WIKIPEDIA

Designer-drugs-Acetylfentanyl

Created by admin on Sat Dec 16 05:26:06 UTC 2023 , Edited by admin on Sat Dec 16 05:26:06 UTC 2023

DEA NO.

9821

Created by admin on Sat Dec 16 05:26:06 UTC 2023 , Edited by admin on Sat Dec 16 05:26:06 UTC 2023

WIKIPEDIA

List_of_fentanyl_analogues

Created by admin on Sat Dec 16 05:26:06 UTC 2023 , Edited by admin on Sat Dec 16 05:26:06 UTC 2023

Code System Code Type Description

RS_ITEM_NUM

1269979

Created by admin on Sat Dec 16 05:26:06 UTC 2023 , Edited by admin on Sat Dec 16 05:26:06 UTC 2023

PRIMARY

WEB RESOURCE

ACETYLFENTANYL

Created by admin on Sat Dec 16 05:26:06 UTC 2023 , Edited by admin on Sat Dec 16 05:26:06 UTC 2023

PRIMARY

EPA CompTox

DTXSID80186275

Created by admin on Sat Dec 16 05:26:06 UTC 2023 , Edited by admin on Sat Dec 16 05:26:06 UTC 2023

PRIMARY

EVMPD

SUB180510

Created by admin on Sat Dec 16 05:26:06 UTC 2023 , Edited by admin on Sat Dec 16 05:26:06 UTC 2023

PRIMARY

FDA UNII

6DZ28538KS

Created by admin on Sat Dec 16 05:26:06 UTC 2023 , Edited by admin on Sat Dec 16 05:26:06 UTC 2023

PRIMARY

CAS

3258-84-2

Created by admin on Sat Dec 16 05:26:06 UTC 2023 , Edited by admin on Sat Dec 16 05:26:06 UTC 2023

PRIMARY

PUBCHEM

527015

Created by admin on Sat Dec 16 05:26:06 UTC 2023 , Edited by admin on Sat Dec 16 05:26:06 UTC 2023

PRIMARY

SMS_ID

100000166398

Created by admin on Sat Dec 16 05:26:06 UTC 2023 , Edited by admin on Sat Dec 16 05:26:06 UTC 2023

PRIMARY

WIKIPEDIA

ACETYLFENTANYL

Created by admin on Sat Dec 16 05:26:06 UTC 2023 , Edited by admin on Sat Dec 16 05:26:06 UTC 2023

PRIMARY

Acetylfentanyl was discovered at the same time as fentanyl itself and had only rarely been encountered on the illicit market in the late 1980s. However, in 2013, Canadian police seized 3 kilograms of acetylfentanyl. As a μ-opioid receptor agonist, acetylfentanyl may serve as a direct substitute for heroin or other opioids. Side effects of fentanyl analogs are similar to those of fentanyl itself, which include itching, nausea and potentially serious respiratory depression, which can be life-threatening.

Related Record Type Details


					G4ZVOWIHLI

ACETYLFENTANYL HYDROCHLORIDE

SALT/SOLVATE -> PARENT


					1PE72K8X46

MU-TYPE OPIOID RECEPTOR

TARGET -> AGONIST

Interaction Type:

BINDING

Qualification:

Ki

Amount:

Related Record Type Details


					UF599785JZ

FENTANYL

PARENT -> IMPURITY

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

USP

Amount:


					MUN5LYG46H

FENTANYL CITRATE

PARENT -> IMPURITY

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

USP

Amount:


					MUN5LYG46H

FENTANYL CITRATE

PARENT -> IMPURITY

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:

Related Record Type Details


					6DZ28538KS

ACTIVE MOIETY

Comments:

ED50(mg/kg) = 0.021, LD50(mg/kg) = 9.3, Potency ratio to morphine = 15.7, Potency ratio to fentanyl = 0.29