IPRINDOLE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C19H28N2
Molecular Weight	284.439
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of IPRINDOLE

Structure Search

SMILES

CN(C)CCCN1C2=C(CCCCCC2)C3=C1C=CC=C3

InChI

InChIKey=PLIGPBGDXASWPX-UHFFFAOYSA-N

InChI=1S/C19H28N2/c1-20(2)14-9-15-21-18-12-6-4-3-5-10-16(18)17-11-7-8-13-19(17)21/h7-8,11,13H,3-6,9-10,12,14-15H2,1-2H3

HIDE SMILES / InChI

Molecular Formula	C19H28N2
Molecular Weight	284.439
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/4870104 | https://www.ncbi.nlm.nih.gov/pubmed/8174513

Iprindole under the brand name Prondol was used as an antidepressant but now is no longer marketed. It possesses the beta-adrenergic properties and has an indirect beta 2-mimetic effect.

Approval Year

PubMed

PubMed

Title	Date	PubMed
Effects of chronic administration of antidepressant drugs on aggressive behavior induced by clonidine in mice.	1980 Aug	6251483
Changes in amphetamine-induced anorexia and stereotypy during chronic treatment with antidepressant drugs.	1984 Mar 2	6586424
The evolution of Indian psychiatric research: An examination of the early decades of the Indian Journal of Psychiatry.	2010 Jan	21836678

Patents

Patents

Sample Use Guides

In Vivo Use Guide

15 mg three times a day

Route of Administration: Oral

Substance Class	Chemical Created by `admin` on `Sat Dec 16 07:44:06 GMT 2023` Edited by `admin` on `Sat Dec 16 07:44:06 GMT 2023`
Record UNII	69U0IKR8FP
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

IPRINDOLE

Official Name

English

5H-CYCLOOCT(B)INDOLE-5-PROPANAMINE, 6,7,8,9,10,11-HEXAHYDRO-N,N-DIMETHYL-

Systematic Name

English

IPRINDOLE [USAN]

Common Name

English

WY-3263

Code

English

IPRINDOLE [MI]

Common Name

English

iprindole [INN]

Common Name

English

NSC-169449

Code

English

Iprindole [WHO-DD]

Common Name

English

5-[3-(Dimethylamino)propyl]-6,7,8,9,10,11-hexahydro-5H-cyclooct[b]indole

Systematic Name

English

Classification Tree Code System Code

WHO-ATC

N06AA13

Created by admin on Sat Dec 16 07:44:06 GMT 2023 , Edited by admin on Sat Dec 16 07:44:06 GMT 2023

WHO-VATC

QN06AA13

Created by admin on Sat Dec 16 07:44:06 GMT 2023 , Edited by admin on Sat Dec 16 07:44:06 GMT 2023

Code System Code Type Description

RXCUI

5979

Created by admin on Sat Dec 16 07:44:06 GMT 2023 , Edited by admin on Sat Dec 16 07:44:06 GMT 2023

PRIMARY

RxNorm

MESH

D007488

Created by admin on Sat Dec 16 07:44:06 GMT 2023 , Edited by admin on Sat Dec 16 07:44:06 GMT 2023

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SMS_ID

100000083123

Created by admin on Sat Dec 16 07:44:06 GMT 2023 , Edited by admin on Sat Dec 16 07:44:06 GMT 2023

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NCI_THESAURUS

C166921

Created by admin on Sat Dec 16 07:44:06 GMT 2023 , Edited by admin on Sat Dec 16 07:44:06 GMT 2023

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ECHA (EC/EINECS)

226-933-5

Created by admin on Sat Dec 16 07:44:06 GMT 2023 , Edited by admin on Sat Dec 16 07:44:06 GMT 2023

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CAS

5560-72-5

Created by admin on Sat Dec 16 07:44:06 GMT 2023 , Edited by admin on Sat Dec 16 07:44:06 GMT 2023

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WIKIPEDIA

IPRINDOLE

Created by admin on Sat Dec 16 07:44:06 GMT 2023 , Edited by admin on Sat Dec 16 07:44:06 GMT 2023

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NSC

169449

Created by admin on Sat Dec 16 07:44:06 GMT 2023 , Edited by admin on Sat Dec 16 07:44:06 GMT 2023

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DRUG BANK

DB13496

Created by admin on Sat Dec 16 07:44:06 GMT 2023 , Edited by admin on Sat Dec 16 07:44:06 GMT 2023

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EPA CompTox

DTXSID80204145

Created by admin on Sat Dec 16 07:44:06 GMT 2023 , Edited by admin on Sat Dec 16 07:44:06 GMT 2023

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DRUG CENTRAL

1478

Created by admin on Sat Dec 16 07:44:06 GMT 2023 , Edited by admin on Sat Dec 16 07:44:06 GMT 2023

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INN

1854

Created by admin on Sat Dec 16 07:44:06 GMT 2023 , Edited by admin on Sat Dec 16 07:44:06 GMT 2023

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PUBCHEM

21722

Created by admin on Sat Dec 16 07:44:06 GMT 2023 , Edited by admin on Sat Dec 16 07:44:06 GMT 2023

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MERCK INDEX

m6389

Created by admin on Sat Dec 16 07:44:06 GMT 2023 , Edited by admin on Sat Dec 16 07:44:06 GMT 2023

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Merck Index

EVMPD

SUB08279MIG

Created by admin on Sat Dec 16 07:44:06 GMT 2023 , Edited by admin on Sat Dec 16 07:44:06 GMT 2023

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ChEMBL

CHEMBL126224

Created by admin on Sat Dec 16 07:44:06 GMT 2023 , Edited by admin on Sat Dec 16 07:44:06 GMT 2023

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FDA UNII

69U0IKR8FP

Created by admin on Sat Dec 16 07:44:06 GMT 2023 , Edited by admin on Sat Dec 16 07:44:06 GMT 2023

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Related Record Type Details


					Z023VDR216

IPRINDOLE HYDROCHLORIDE

SALT/SOLVATE -> PARENT

Related Record Type Details


					69U0IKR8FP

IPRINDOLE

ACTIVE MOIETY