IPRINDOLE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C19H28N2
Molecular Weight	284.439
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CN(C)CCCN1C2=C(CCCCCC2)C3=C1C=CC=C3

InChI

InChIKey=PLIGPBGDXASWPX-UHFFFAOYSA-N

InChI=1S/C19H28N2/c1-20(2)14-9-15-21-18-12-6-4-3-5-10-16(18)17-11-7-8-13-19(17)21/h7-8,11,13H,3-6,9-10,12,14-15H2,1-2H3

HIDE SMILES / InChI

Molecular Formula	C19H28N2
Molecular Weight	284.439
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/4870104 | https://www.ncbi.nlm.nih.gov/pubmed/8174513

Iprindole under the brand name Prondol was used as an antidepressant but now is no longer marketed. It possesses the beta-adrenergic properties and has an indirect beta 2-mimetic effect.

Approval Year

PubMed

Title	Date	PubMed
Getting the balance right: Established and emerging therapies for major depressive disorders.	2010-09-07	20856599
Research on antidepressants in India.	2010-01	21836704
The evolution of Indian psychiatric research: An examination of the early decades of the Indian Journal of Psychiatry.	2010-01	21836678
Contribution of sleep research to the development of new antidepressants.	2005	16416706
Adverse pulmonary vascular effects of high dose tricyclic antidepressants: acute and chronic animal studies.	2002-08	12212966
3,4-Methylenedioxymethamphetamine produces glycogenolysis and increases the extracellular concentration of glucose in the rat brain.	2002-04	11907167
Prenatal exposure of rats to antidepressants enhances agonist affinity of brain dopamine receptors and dopamine-mediated behaviour.	1985-10-22	3841069
Changes in amphetamine-induced anorexia and stereotypy during chronic treatment with antidepressant drugs.	1984-03-02	6586424
Effects of chronic administration of antidepressant drugs on aggressive behavior induced by clonidine in mice.	1980-08	6251483
Chronic treatment with antidepressant drugs: potentiation of apomorphine-induced aggressive behaviour in rats.	1979-08	575199
Experimental myopathy induced by amphiphilic cationic compounds including several psychotropic drugs.	1979	34807

Patents

Sample Use Guides

In Vivo Use Guide

15 mg three times a day

Route of Administration: Oral

Substance Class	Chemical Created by `admin` on `Mon Mar 31 21:43:24 GMT 2025` Edited by `admin` on `Mon Mar 31 21:43:24 GMT 2025`
Record UNII	69U0IKR8FP
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

IPRINDOLE

Official Name

English

NSC-169449

Preferred Name

English

5H-CYCLOOCT(B)INDOLE-5-PROPANAMINE, 6,7,8,9,10,11-HEXAHYDRO-N,N-DIMETHYL-

Systematic Name

English

IPRINDOLE [USAN]

Common Name

English

WY-3263

Code

English

IPRINDOLE [MI]

Common Name

English

iprindole [INN]

Common Name

English

Iprindole [WHO-DD]

Common Name

English

5-[3-(Dimethylamino)propyl]-6,7,8,9,10,11-hexahydro-5H-cyclooct[b]indole

Systematic Name

English

Classification Tree Code System Code

WHO-ATC

N06AA13