IPRINDOLE HYDROCHLORIDE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C19H28N2.ClH
Molecular Weight	320.9
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

Cl.CN(C)CCCN1C2=C(CCCCCC2)C3=C1C=CC=C3

InChI

InChIKey=ZQUYTAXPERMDKM-UHFFFAOYSA-N

InChI=1S/C19H28N2.ClH/c1-20(2)14-9-15-21-18-12-6-4-3-5-10-16(18)17-11-7-8-13-19(17)21;/h7-8,11,13H,3-6,9-10,12,14-15H2,1-2H3;1H

HIDE SMILES / InChI

Molecular Formula	C19H28N2
Molecular Weight	284.439
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	ClH
Molecular Weight	36.461
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/4870104 | https://www.ncbi.nlm.nih.gov/pubmed/8174513

Iprindole under the brand name Prondol was used as an antidepressant but now is no longer marketed. It possesses the beta-adrenergic properties and has an indirect beta 2-mimetic effect.

Approval Year

PubMed

Title	Date	PubMed
Experimental myopathy induced by amphiphilic cationic compounds including several psychotropic drugs.	1979	34807
Chronic treatment with antidepressant drugs: potentiation of apomorphine-induced aggressive behaviour in rats.	1979 Aug	575199
Effects of chronic administration of antidepressant drugs on aggressive behavior induced by clonidine in mice.	1980 Aug	6251483
Changes in amphetamine-induced anorexia and stereotypy during chronic treatment with antidepressant drugs.	1984 Mar 2	6586424
Prenatal exposure of rats to antidepressants enhances agonist affinity of brain dopamine receptors and dopamine-mediated behaviour.	1985 Oct 22	3841069
3,4-Methylenedioxymethamphetamine produces glycogenolysis and increases the extracellular concentration of glucose in the rat brain.	2002 Apr	11907167
Adverse pulmonary vascular effects of high dose tricyclic antidepressants: acute and chronic animal studies.	2002 Aug	12212966
Contribution of sleep research to the development of new antidepressants.	2005	16416706
Research on antidepressants in India.	2010 Jan	21836704
The evolution of Indian psychiatric research: An examination of the early decades of the Indian Journal of Psychiatry.	2010 Jan	21836678
Getting the balance right: Established and emerging therapies for major depressive disorders.	2010 Sep 7	20856599

Patents

Sample Use Guides

In Vivo Use Guide

15 mg three times a day

Route of Administration: Oral

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:04:14 GMT 2023` Edited by `admin` on `Fri Dec 15 15:04:14 GMT 2023`
Record UNII	Z023VDR216
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

IPRINDOLE HYDROCHLORIDE

Common Name

English

IPRINDOLE HYDROCHLORIDE [MI]

Common Name

English

IPRINDOLE HYDROCHLORIDE [MART.]

Common Name

English

IPRINDOLE HCL

Common Name

English

Iprindole hydrochloride [WHO-DD]

Common Name

English

6,7,8,9,10,11-HEXAHYDRO-N,N-DIMETHYL-5H-CYCLOOCT)(B)INDOLE-5-PROPANAMINE, HYDROCHLORIDE

Common Name

English

Code System Code Type Description

FDA UNII

Z023VDR216