Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C18H18N2O |
| Molecular Weight | 278.3483 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CN1CCC(CC1)=C2C3=CC=CC=C3OC4=NC=CC=C24
InChI
InChIKey=ALIOEEFZPKWPAV-UHFFFAOYSA-N
InChI=1S/C18H18N2O/c1-20-11-8-13(9-12-20)17-14-5-2-3-7-16(14)21-18-15(17)6-4-10-19-18/h2-7,10H,8-9,11-12H2,1H3
| Molecular Formula | C18H18N2O |
| Molecular Weight | 278.3483 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Azanator (previously known as Sch 15280), a bronchodilator and an antihistamine drug that acts via a non-adrenergic mechanism to block both histaminergically and cholinergically mediated responses in the tracheobronchial tree. Besides, the drug inhibits cyclic CMP phosphodiesterase. Azanator can have a therapeutic application in cases of chronic cough and cystic fibrosis in man.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Differential effects of various phosphodiesterase inhibitors, pyrimidine and purine compounds, and inorganic phosphates on cyclic CMP, cyclic AMP and cyclic GMP phosphodiesterases. | 1982-01-01 |
|
| Effect of SCH 15280, a new bronchodilator, on cyclic 3',5'-nucleotide phosphodiesterase activity and cyclic 3',5'-adenosine monophosphate levels in guinea pig lung. | 1977-05-15 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Wed Apr 02 09:23:58 GMT 2025
by
admin
on
Wed Apr 02 09:23:58 GMT 2025
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| Record UNII |
699725286I
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| Record Status |
Validated (UNII)
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| Record Version |
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NCI_THESAURUS |
C319
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SALT/SOLVATE -> PARENT |
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ACTIVE MOIETY |
