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Details

Stereochemistry ACHIRAL
Molecular Formula C18H18N2O.C4H4O4
Molecular Weight 394.4205
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 1
Charge 0

SHOW SMILES / InChI
Structure of AZANATOR MALEATE

SMILES

OC(=O)\C=C/C(O)=O.CN1CCC(CC1)=C2C3=C(OC4=C2C=CC=N4)C=CC=C3

InChI

InChIKey=QXBGSDYYBBNBPB-BTJKTKAUSA-N
InChI=1S/C18H18N2O.C4H4O4/c1-20-11-8-13(9-12-20)17-14-5-2-3-7-16(14)21-18-15(17)6-4-10-19-18;5-3(6)1-2-4(7)8/h2-7,10H,8-9,11-12H2,1H3;1-2H,(H,5,6)(H,7,8)/b;2-1-

HIDE SMILES / InChI
Molecular Formula C4H4O4
Molecular Weight 116.0722
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 1
Optical Activity NONE
Molecular Formula C18H18N2O
Molecular Weight 278.3483
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Azanator (previously known as Sch 15280), a bronchodilator and an antihistamine drug that acts via a non-adrenergic mechanism to block both histaminergically and cholinergically mediated responses in the tracheobronchial tree. Besides, the drug inhibits cyclic CMP phosphodiesterase. Azanator can have a therapeutic application in cases of chronic cough and cystic fibrosis in man.

Approval Year

Unknown
139594
PubMed

PubMed

TitleDatePubMed
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:32:58 GMT 2023
Edited
by admin
on Fri Dec 15 15:32:58 GMT 2023
Record UNII
63ISF1PDWX
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
AZANATOR MALEATE
USAN  
USAN  
Official Name English
AZANATOR MALEATE [USAN]
Common Name English
5H-(1)BENZOPYRANO(2,3-B)PYRIDINE, 5-(1-METHYL-4-PIPERIDINYLIDENE)-, (Z)-2-BUTENEDIOATE (1:1)
Systematic Name English
SCH-15280
Code English
5-(1-Methyl-4-piperidylidene)-5H-[1]benzopyrano[2,3-b]pyridine maleate (1:1)
Systematic Name English
5-(4-(N-METHYL)-PIPERIDYLIDENE)-5H-(1)-BENZOPYRANO(2,3-B)PYRIDINE MALEATE
Common Name English
NSC-295279
Code English
SCH 15280
Code English
Classification Tree Code System Code
NCI_THESAURUS C319
Created by admin on Fri Dec 15 15:32:59 GMT 2023 , Edited by admin on Fri Dec 15 15:32:59 GMT 2023
Code System Code Type Description
NCI_THESAURUS
C74219
Created by admin on Fri Dec 15 15:32:59 GMT 2023 , Edited by admin on Fri Dec 15 15:32:59 GMT 2023
PRIMARY
CAS
39624-65-2
Created by admin on Fri Dec 15 15:32:59 GMT 2023 , Edited by admin on Fri Dec 15 15:32:59 GMT 2023
PRIMARY
FDA UNII
63ISF1PDWX
Created by admin on Fri Dec 15 15:32:59 GMT 2023 , Edited by admin on Fri Dec 15 15:32:59 GMT 2023
PRIMARY
ChEMBL
CHEMBL2110934
Created by admin on Fri Dec 15 15:32:59 GMT 2023 , Edited by admin on Fri Dec 15 15:32:59 GMT 2023
PRIMARY
NSC
295279
Created by admin on Fri Dec 15 15:32:59 GMT 2023 , Edited by admin on Fri Dec 15 15:32:59 GMT 2023
PRIMARY
PUBCHEM
5359048
Created by admin on Fri Dec 15 15:32:59 GMT 2023 , Edited by admin on Fri Dec 15 15:32:59 GMT 2023
PRIMARY
Related Record Type Details
Structure of MALEIC ACID
PARENT -> SALT/SOLVATE
Structure of AZANATOR
PARENT -> SALT/SOLVATE
Related Record Type Details
Structure of AZANATOR
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