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Details

Stereochemistry RACEMIC
Molecular Formula C3H5O3.H4N
Molecular Weight 107.1085
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of Ammonium lactate

SMILES

[NH4+].CC(O)C([O-])=O

InChI

InChIKey=RZOBLYBZQXQGFY-UHFFFAOYSA-N
InChI=1S/C3H6O3.H3N/c1-2(4)3(5)6;/h2,4H,1H3,(H,5,6);1H3

HIDE SMILES / InChI

Molecular Formula H3N
Molecular Weight 17.0305
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula C3H6O3
Molecular Weight 90.0779
Charge 0
Count
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 0
Optical Activity ( + / - )

Description
Curator's Comment: Description was created based on several sources, including https://www.brambleberry.com/sodium-lactate-p5127.aspx | http://www.fbcindustries.com/Sodium_Lactate.aspx

Sodium lactate is primarily indicated as a source of bicarbonate for prevention or control of mild to moderate metabolic acidosis in patients with restricted oral intake whose oxidative processes are not seriously impaired. Sodium Lactate is most commonly associated with an E number of “E325” Sodium Lactate blends are commonly used in meat and poultry products to extend shelf life and increase food safety. They have a broad antimicrobial action and are effective at inhibiting most spoilage and pathogenic bacteria. In addition sodium lactate is used in cosmetics as a humectant, providing moisture.

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
SODIUM LACTATE IN PLASTIC CONTAINER

Approved Use

Sodium Lactate Injection, USP 50 mEq (5 mEq/mL), is primarily indicated, after dilution, as a source of bicarbonate for prevention or control of mild to moderate metabolic acidosis in patients with restricted oral intake whose oxidative processes are not seriously impaired. It is not intended nor effective for correcting severe acidotic states which require immediate restoration of plasma bicarbonate levels. Sodium lactate has no advantage over sodium bicarbonate and may be detrimental in the management of lactic acidosis

Launch Date

4.63103984E11
Cmax

Cmax

ValueDoseCo-administeredAnalytePopulation
20.2 μg/mL
39.76 mmol other, intravenous
dose: 39.76 mmol
route of administration: Intravenous
experiment type: OTHER
co-administered:
LACTATE ION, L- plasma
Homo sapiens
population: UNHEALTHY
age: ADULT
sex: FEMALE / MALE
food status: UNKNOWN
2.03 mg/dL
39.76 mmol other, intravenous
dose: 39.76 mmol
route of administration: Intravenous
experiment type: OTHER
co-administered:
LACTIC ACID, D- plasma
Homo sapiens
population: UNHEALTHY
age: ADULT
sex: FEMALE / MALE
food status: UNKNOWN
AUC

AUC

ValueDoseCo-administeredAnalytePopulation
53.35 mg × h/dL
39.76 mmol other, intravenous
dose: 39.76 mmol
route of administration: Intravenous
experiment type: OTHER
co-administered:
LACTATE ION, L- plasma
Homo sapiens
population: UNHEALTHY
age: ADULT
sex: FEMALE / MALE
food status: UNKNOWN
4.44 mg × h/dL
39.76 mmol other, intravenous
dose: 39.76 mmol
route of administration: Intravenous
experiment type: OTHER
co-administered:
LACTIC ACID, D- plasma
Homo sapiens
population: UNHEALTHY
age: ADULT
sex: FEMALE / MALE
food status: UNKNOWN
Sourcing

Sourcing

Vendor/AggregatorIDURL
PubMed

PubMed

TitleDatePubMed
Physiological and behavioral effects of naloxone and lactate in normal volunteers with relevance to the pathophysiology of panic disorder.
2007 Jan 15
Patents

Sample Use Guides

Sodium Lactate Injection, USP 50 mEq (5 mEq/mL) is administered intravenously only after addition to a larger volume of fluid. The amount of sodium ion and lactate ion to be added to larger volume intravenous fluids should be determined in accordance with the electrolyte requirements of each individual patient. All or part of the content(s) of one (50 mEq in 10 mL) or more vial containers may be added to other intravenous solutions to provide any desired number of milliequivalents of lactate anion (with the same number of milliequivalents of Na+ ). The contents of one container (50 mEq in 10 mL) added to 290 mL of a nonelectrolyte solution or of sterile water for injection will provide 300 mL of an approximately isotonic (1/6 molar) concentration of sodium lactate (1.9%), containing 167 mEq/liter each of Na+ and lactate anion
Route of Administration: Intravenous
10 mM sodium lactate inhibits activated T cell motility
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:31:04 UTC 2023
Edited
by admin
on Fri Dec 15 15:31:04 UTC 2023
Record UNII
67M901L9NQ
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
Ammonium lactate
INCI   MART.   MI   ORANGE BOOK   USAN   VANDF   WHO-DD  
INCI   USAN  
Official Name English
AMMONIUM (±)-LACTATE
Systematic Name English
AMMONIUM LACTATE [VANDF]
Common Name English
LAC-HYDRIN
Brand Name English
PROPANOIC ACID, 2-HYDROXY-, AMMONIUM SALT (1:1)
Common Name English
BMS-186091
Code English
AMMONIUM LACTATE [MART.]
Common Name English
Ammonium lactate [WHO-DD]
Common Name English
PROPANOIC ACID, 2-HYDROXY-, MONOAMMONIUM SALT
Common Name English
AMMONIUM LACTATE [USAN]
Common Name English
AMMONIUM LACTATE [INCI]
Common Name English
NSC-760427
Code English
AMMONIUM LACTATE [MI]
Common Name English
PROPANOIC ACID, 2-HYDROXY-, MONOAMMONIUM SALT, (±)-
Common Name English
LAC HYDRIN
Brand Name English
AMMONIUM LACTATE [ORANGE BOOK]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C29639
Created by admin on Fri Dec 15 15:31:04 UTC 2023 , Edited by admin on Fri Dec 15 15:31:04 UTC 2023
NDF-RT N0000007983
Created by admin on Fri Dec 15 15:31:04 UTC 2023 , Edited by admin on Fri Dec 15 15:31:04 UTC 2023
NDF-RT N0000175842
Created by admin on Fri Dec 15 15:31:04 UTC 2023 , Edited by admin on Fri Dec 15 15:31:04 UTC 2023
WHO-VATC QA16QA04
Created by admin on Fri Dec 15 15:31:04 UTC 2023 , Edited by admin on Fri Dec 15 15:31:04 UTC 2023
Code System Code Type Description
EVMPD
SUB12879MIG
Created by admin on Fri Dec 15 15:31:04 UTC 2023 , Edited by admin on Fri Dec 15 15:31:04 UTC 2023
PRIMARY
DAILYMED
67M901L9NQ
Created by admin on Fri Dec 15 15:31:04 UTC 2023 , Edited by admin on Fri Dec 15 15:31:04 UTC 2023
PRIMARY
EPA CompTox
DTXSID3052808
Created by admin on Fri Dec 15 15:31:04 UTC 2023 , Edited by admin on Fri Dec 15 15:31:04 UTC 2023
PRIMARY
MERCK INDEX
m1797
Created by admin on Fri Dec 15 15:31:04 UTC 2023 , Edited by admin on Fri Dec 15 15:31:04 UTC 2023
PRIMARY Merck Index
DRUG BANK
DB06768
Created by admin on Fri Dec 15 15:31:04 UTC 2023 , Edited by admin on Fri Dec 15 15:31:04 UTC 2023
PRIMARY
MESH
C114389
Created by admin on Fri Dec 15 15:31:04 UTC 2023 , Edited by admin on Fri Dec 15 15:31:04 UTC 2023
PRIMARY
CAS
515-98-0
Created by admin on Fri Dec 15 15:31:04 UTC 2023 , Edited by admin on Fri Dec 15 15:31:04 UTC 2023
PRIMARY
WIKIPEDIA
AMMONIUM LACTATE
Created by admin on Fri Dec 15 15:31:04 UTC 2023 , Edited by admin on Fri Dec 15 15:31:04 UTC 2023
PRIMARY
NCI_THESAURUS
C28821
Created by admin on Fri Dec 15 15:31:04 UTC 2023 , Edited by admin on Fri Dec 15 15:31:04 UTC 2023
PRIMARY
DRUG CENTRAL
4476
Created by admin on Fri Dec 15 15:31:04 UTC 2023 , Edited by admin on Fri Dec 15 15:31:04 UTC 2023
PRIMARY
ECHA (EC/EINECS)
208-214-8
Created by admin on Fri Dec 15 15:31:04 UTC 2023 , Edited by admin on Fri Dec 15 15:31:04 UTC 2023
PRIMARY
RXCUI
215247
Created by admin on Fri Dec 15 15:31:04 UTC 2023 , Edited by admin on Fri Dec 15 15:31:04 UTC 2023
PRIMARY RxNorm
NSC
760427
Created by admin on Fri Dec 15 15:31:04 UTC 2023 , Edited by admin on Fri Dec 15 15:31:04 UTC 2023
PRIMARY
USAN
GG-46
Created by admin on Fri Dec 15 15:31:04 UTC 2023 , Edited by admin on Fri Dec 15 15:31:04 UTC 2023
PRIMARY
PUBCHEM
62358
Created by admin on Fri Dec 15 15:31:04 UTC 2023 , Edited by admin on Fri Dec 15 15:31:04 UTC 2023
PRIMARY
ChEMBL
CHEMBL1200747
Created by admin on Fri Dec 15 15:31:04 UTC 2023 , Edited by admin on Fri Dec 15 15:31:04 UTC 2023
PRIMARY
FDA UNII
67M901L9NQ
Created by admin on Fri Dec 15 15:31:04 UTC 2023 , Edited by admin on Fri Dec 15 15:31:04 UTC 2023
PRIMARY
SMS_ID
100000077924
Created by admin on Fri Dec 15 15:31:04 UTC 2023 , Edited by admin on Fri Dec 15 15:31:04 UTC 2023
PRIMARY
Related Record Type Details
PARENT -> SALT/SOLVATE
Related Record Type Details
ACTIVE MOIETY
ACTIVE MOIETY