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Details

Stereochemistry ACHIRAL
Molecular Formula Cl.K
Molecular Weight 74.551
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of Potassium chloride

SMILES

[Cl-].[K+]

InChI

InChIKey=WCUXLLCKKVVCTQ-UHFFFAOYSA-M
InChI=1S/ClH.K/h1H;/q;+1/p-1

HIDE SMILES / InChI
Molecular Formula ClH
Molecular Weight 36.461
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula K
Molecular Weight 39.0983
Charge 1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Potassium is needed to maintain good health. When potassium level falls below 3.5 mmol/L, Hypokalemia is diagnosed. In case of extremely low level of potassium (lower than 2.5 mmol/L) the following symptoms are appeared: malaise and fatigue. This low level of potassium can lead to severe muscle weakness and paralysis; respiratory failure; intermittent muscle spasms. It is known, foods that are good sources of potassium and low in sodium may reduce the risk of high blood pressure and stroke. Potassium supplementation is also recommended as an adjuvant antihypertensive agent for patients with essential hypertension.

Approval Year

1921
1468
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Palliative
Phase III
665
Unknown

Approved Use

Unknown
PubMed

PubMed

TitleDatePubMed
Mineral and water nutrition.
1991 Jul
Age sensitivity to organophosphate-induced delayed polyneuropathy. Biochemical and toxicological studies in developing chicks.
1991 May 15
Diet, genetics and hypertension.
1997 Aug
Delay of natural bone loss by higher intakes of specific minerals and vitamins.
2001 May
Crystal structures of Tritrichomonasfoetus inosine monophosphate dehydrogenase in complex with substrate, cofactor and analogs: a structural basis for the random-in ordered-out kinetic mechanism.
2003 Feb 14
Patents

Patents

03932629
17
03956321
16
03959289
17
03970704
18
04008269
18
04029867
16
04511731
16
04532240
16
04568497
17
04691042
16
05187175
16
05302718
20
05403930
17
05556855
19
07250518
16
07354941
42
07655666
16
08012988
16
08436001
19
08481733
20
08513268
16
08614206
16
08669361
18
08741915
18
20030186989
17
20080153836
17
20090286768
16
20100144747
17
20110251176
16
20110294818
16
20120208817
16
20130079321
16
20130203732
16
20130217666
16

Sample Use Guides

In Vivo Use Guide
Potassium is administered in various dosage forms (gluconate, citrate, chloride, bicarbonate). Exact dose should be determined by a doctor. Most people will not take more than 100 mEq a day.
Route of Administration: Oral
Substance Class Chemical
Created
by admin
on Mon Mar 31 21:24:16 GMT 2025
Edited
by admin
on Mon Mar 31 21:24:16 GMT 2025
Record UNII
660YQ98I10
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
KALI MURIATICUM
HPUS  
Preferred Name English
Potassium chloride
EP   FCC   HSDB   II   INCI   MART.   MI   ORANGE BOOK   USP   USP-RS   VANDF   WHO-DD   WHO-IP  
INCI  
Official Name English
E-508
Code English
KLOR-CON
Brand Name English
KLOTRIX
Brand Name English
MICRO-K
Brand Name English
POTASSIUM (AS CHLORIDE) [VANDF]
Common Name English
MICRO-K 10
Brand Name English
POTASSIUM CHLORIDE [MI]
Common Name English
NSC-77368
Code English
POTASSIUM CHLORIDE [VANDF]
Common Name English
POTASSIUM CHLORIDE [WHO-IP]
Common Name English
E 508
Code English
POTASSIUM(I) CHLORIDE
Systematic Name English
Potassium chloride [WHO-DD]
Common Name English
TIS-U-SOL COMPONENT POTASSIUM CHLORIDE
Common Name English
INS-508
Code English
CHLORIDE (AS POTASSIUM)
VANDF  
Common Name English
K-TAB
Brand Name English
TEN-K
Brand Name English
THAM-E COMPONENT POTASSIUM CHLORIDE
Common Name English
POTASSIUM CHLORIDE [USP MONOGRAPH]
Common Name English
NEOBAKASAL
Common Name English
POTASSIUM CHLORIDE [HSDB]
Common Name English
KALI MURIATICUM [HPUS]
Common Name English
KAON CL-10
Brand Name English
POTASSIUM CHLORIDE [USP-RS]
Common Name English
POTASSIUM CHLORIDE [FCC]
Common Name English
MultiBic component potassium chloride
Brand Name English
CHLORIDE (AS POTASSIUM) [VANDF]
Common Name English
INS NO.508
Code English
POTASSIUM CHLORIDE [MART.]
Common Name English
HALFLYTELY COMPONENT POTASSIUM CHLORIDE
Common Name English
POTASSIUM CHLORIDE [ORANGE BOOK]
Common Name English
SYLVINE
Common Name English
SLOW-K
Brand Name English
K+10
Brand Name English
POTASSIUM CHLORIDE [EP MONOGRAPH]
Common Name English
KCL
Common Name English
POTASSIUM CHLORIDE [II]
Common Name English
B1653 [LANGUAL]
Code English
K-LEASE
Brand Name English
KALII CHLORIDUM [WHO-IP LATIN]
Common Name English
MICRO-K LS
Brand Name English
POTASSIUM MONOCHLORIDE
Systematic Name English
K+8
Brand Name English
POTASSIUM CHLORIDE [JAN]
Common Name English
KAON CL
Brand Name English
SYLVITE
Common Name English
Classification Tree Code System Code
CFR 21 CFR 184.1622
Created by admin on Mon Mar 31 21:24:16 GMT 2025 , Edited by admin on Mon Mar 31 21:24:16 GMT 2025
WHO-ESSENTIAL MEDICINES LIST 26.1
Created by admin on Mon Mar 31 21:24:16 GMT 2025 , Edited by admin on Mon Mar 31 21:24:16 GMT 2025
WHO-ATC B05XA01
Created by admin on Mon Mar 31 21:24:16 GMT 2025 , Edited by admin on Mon Mar 31 21:24:16 GMT 2025
WHO-VATC QA12BA01
Created by admin on Mon Mar 31 21:24:16 GMT 2025 , Edited by admin on Mon Mar 31 21:24:16 GMT 2025
JECFA EVALUATION INS-508
Created by admin on Mon Mar 31 21:24:16 GMT 2025 , Edited by admin on Mon Mar 31 21:24:16 GMT 2025
NCI_THESAURUS C29730
Created by admin on Mon Mar 31 21:24:16 GMT 2025 , Edited by admin on Mon Mar 31 21:24:16 GMT 2025
WHO-VATC QB05XA01
Created by admin on Mon Mar 31 21:24:16 GMT 2025 , Edited by admin on Mon Mar 31 21:24:16 GMT 2025
CFR 21 CFR 216.24
Created by admin on Mon Mar 31 21:24:16 GMT 2025 , Edited by admin on Mon Mar 31 21:24:16 GMT 2025
DSLD 2903 (Number of products:117)
Created by admin on Mon Mar 31 21:24:16 GMT 2025 , Edited by admin on Mon Mar 31 21:24:16 GMT 2025
WHO-ATC A12BA01
Created by admin on Mon Mar 31 21:24:16 GMT 2025 , Edited by admin on Mon Mar 31 21:24:16 GMT 2025
EPA PESTICIDE CODE 13904
Created by admin on Mon Mar 31 21:24:16 GMT 2025 , Edited by admin on Mon Mar 31 21:24:16 GMT 2025
FDA ORPHAN DRUG 403513
Created by admin on Mon Mar 31 21:24:16 GMT 2025 , Edited by admin on Mon Mar 31 21:24:16 GMT 2025
WHO-ESSENTIAL MEDICINES LIST 26.2
Created by admin on Mon Mar 31 21:24:16 GMT 2025 , Edited by admin on Mon Mar 31 21:24:16 GMT 2025
FDA ORPHAN DRUG 616817
Created by admin on Mon Mar 31 21:24:16 GMT 2025 , Edited by admin on Mon Mar 31 21:24:16 GMT 2025
WHO-VATC QA12BA51
Created by admin on Mon Mar 31 21:24:16 GMT 2025 , Edited by admin on Mon Mar 31 21:24:16 GMT 2025
WHO-ATC A12BA51
Created by admin on Mon Mar 31 21:24:16 GMT 2025 , Edited by admin on Mon Mar 31 21:24:16 GMT 2025
CODEX ALIMENTARIUS (GSFA) INS-508
Created by admin on Mon Mar 31 21:24:16 GMT 2025 , Edited by admin on Mon Mar 31 21:24:16 GMT 2025
Code System Code Type Description
CAS
7447-40-7
Created by admin on Mon Mar 31 21:24:16 GMT 2025 , Edited by admin on Mon Mar 31 21:24:16 GMT 2025
PRIMARY
FDA UNII
660YQ98I10
Created by admin on Mon Mar 31 21:24:16 GMT 2025 , Edited by admin on Mon Mar 31 21:24:16 GMT 2025
PRIMARY
CHEBI
32588
Created by admin on Mon Mar 31 21:24:16 GMT 2025 , Edited by admin on Mon Mar 31 21:24:16 GMT 2025
PRIMARY
NSC
77368
Created by admin on Mon Mar 31 21:24:16 GMT 2025 , Edited by admin on Mon Mar 31 21:24:16 GMT 2025
PRIMARY
ECHA (EC/EINECS)
231-211-8
Created by admin on Mon Mar 31 21:24:16 GMT 2025 , Edited by admin on Mon Mar 31 21:24:16 GMT 2025
PRIMARY
RXCUI
8591
Created by admin on Mon Mar 31 21:24:16 GMT 2025 , Edited by admin on Mon Mar 31 21:24:16 GMT 2025
PRIMARY RxNorm
NCI_THESAURUS
C47679
Created by admin on Mon Mar 31 21:24:16 GMT 2025 , Edited by admin on Mon Mar 31 21:24:16 GMT 2025
PRIMARY
ChEMBL
CHEMBL1200731
Created by admin on Mon Mar 31 21:24:16 GMT 2025 , Edited by admin on Mon Mar 31 21:24:16 GMT 2025
PRIMARY
RS_ITEM_NUM
1548190
Created by admin on Mon Mar 31 21:24:16 GMT 2025 , Edited by admin on Mon Mar 31 21:24:16 GMT 2025
PRIMARY
WIKIPEDIA
POTASSIUM CHLORIDE
Created by admin on Mon Mar 31 21:24:16 GMT 2025 , Edited by admin on Mon Mar 31 21:24:16 GMT 2025
PRIMARY
DAILYMED
660YQ98I10
Created by admin on Mon Mar 31 21:24:16 GMT 2025 , Edited by admin on Mon Mar 31 21:24:16 GMT 2025
PRIMARY
PUBCHEM
4873
Created by admin on Mon Mar 31 21:24:16 GMT 2025 , Edited by admin on Mon Mar 31 21:24:16 GMT 2025
PRIMARY
WHO INTERNATIONAL PHARMACOPEIA
POTASSIUM CHLORIDE
Created by admin on Mon Mar 31 21:24:16 GMT 2025 , Edited by admin on Mon Mar 31 21:24:16 GMT 2025
PRIMARY Description: Colourless crystals or a white, crystalline powder; odourless. Solubility: Soluble in 3 parts of water; practically insoluble in ethanol (~750 g/l) TS. Category: Ionic equilibration agent. Storage: Potassium chloride should be kept in a well-closed container.Labelling. The designation Potassium chloride for parenteral use indicates that the substance complies with the additionalrequirement given at the end of this monograph and may be used for parenteral administration or for other sterile applications. Definition: Potassium chloride contains not less than 99.0% and not more than 100.5% of KCl, calculated with reference to thedried substance.
SMS_ID
100000091807
Created by admin on Mon Mar 31 21:24:16 GMT 2025 , Edited by admin on Mon Mar 31 21:24:16 GMT 2025
PRIMARY
EVMPD
SUB12559MIG
Created by admin on Mon Mar 31 21:24:16 GMT 2025 , Edited by admin on Mon Mar 31 21:24:16 GMT 2025
PRIMARY
DRUG BANK
DB00761
Created by admin on Mon Mar 31 21:24:16 GMT 2025 , Edited by admin on Mon Mar 31 21:24:16 GMT 2025
PRIMARY
EPA CompTox
DTXSID5021178
Created by admin on Mon Mar 31 21:24:16 GMT 2025 , Edited by admin on Mon Mar 31 21:24:16 GMT 2025
PRIMARY
MERCK INDEX
m9012
Created by admin on Mon Mar 31 21:24:16 GMT 2025 , Edited by admin on Mon Mar 31 21:24:16 GMT 2025
PRIMARY Merck Index
WIKIPEDIA
Potassium chloride (medical use)
Created by admin on Mon Mar 31 21:24:16 GMT 2025 , Edited by admin on Mon Mar 31 21:24:16 GMT 2025
PRIMARY
HSDB
1252
Created by admin on Mon Mar 31 21:24:16 GMT 2025 , Edited by admin on Mon Mar 31 21:24:16 GMT 2025
PRIMARY
MESH
D011189
Created by admin on Mon Mar 31 21:24:16 GMT 2025 , Edited by admin on Mon Mar 31 21:24:16 GMT 2025
PRIMARY
DRUG CENTRAL
4199
Created by admin on Mon Mar 31 21:24:16 GMT 2025 , Edited by admin on Mon Mar 31 21:24:16 GMT 2025
PRIMARY
Related Record Type Details
Structure of POTASSIUM CATION
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Route of Elimination PHARMACOKINETIC
MAXIMUM TOLERATED DOSE TOXICITY SERUM POTASSIUM GREATER THAN 2.5 mEq/L: 200 mEq PER 24 HOURS

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