MEFENIDRAMIUM

Details

Stereochemistry	ACHIRAL
Molecular Formula	C18H24NO
Molecular Weight	270.3893
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	1

SHOW SMILES / InChI

Structure Search

SMILES

C[N+](C)(C)CCOC(C1=CC=CC=C1)C2=CC=CC=C2

InChI

InChIKey=LTWUEHSXIKQTIK-UHFFFAOYSA-N

InChI=1S/C18H24NO/c1-19(2,3)14-15-20-18(16-10-6-4-7-11-16)17-12-8-5-9-13-17/h4-13,18H,14-15H2,1-3H3/q+1

HIDE SMILES / InChI

Molecular Formula	C18H24NO
Molecular Weight	270.3893
Charge	1
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/13422668 | https://www.ncbi.nlm.nih.gov/pubmed/4398815

Mefenidramium is an active ingredient of the Danish drug Paradryl that was used to treat pruritus with varicella and as a palliative treatment of estival rhinitis in children.

Approval Year

PubMed

Title	Date	PubMed
Paradryl ointment and Ido tar; two new remedies for the treatment of Besnier's prurigo and eczema.	1951	14894074
[Paradryl salve and ido tar, two new preparations for Besnier's prurigo and eczema].	1951 Nov 29	14922568
Behavioral thermoregulation in the study of drugs affecting body temperature.	1975 Nov-Dec	1223894

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:00:13 GMT 2023` Edited by `admin` on `Fri Dec 15 16:00:13 GMT 2023`
Record UNII	65AZ72LF4X
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

MEFENIDRAMIUM

Common Name

English

(2-(DIPHENYLMETHOXY)ETHYL)TRIMETHYLAMMONIUM

Systematic Name

English

Mefenidramium [WHO-DD]

Common Name

English

MEFENIDRAMIUM ION

Common Name

English

ETHANAMINIUM, 2-(DIPHENYLMETHOXY)-N,N,N-TRIMETHYL-

Systematic Name

English

MEFENIDRAMIUM CATION

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29578