MEFENIDRAMIUM BROMIDE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C18H24NO.Br
Molecular Weight	350.293
Optical Activity	NONE
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[Br-].C[N+](C)(C)CCOC(C1=CC=CC=C1)C2=CC=CC=C2

InChI

InChIKey=BDQPXVWYFLTETB-UHFFFAOYSA-M

InChI=1S/C18H24NO.BrH/c1-19(2,3)14-15-20-18(16-10-6-4-7-11-16)17-12-8-5-9-13-17;/h4-13,18H,14-15H2,1-3H3;1H/q+1;/p-1

HIDE SMILES / InChI

Molecular Formula	BrH
Molecular Weight	80.912
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C18H24NO
Molecular Weight	270.3893
Charge	1
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/13422668 | https://www.ncbi.nlm.nih.gov/pubmed/4398815

Mefenidramium is an active ingredient of the Danish drug Paradryl that was used to treat pruritus with varicella and as a palliative treatment of estival rhinitis in children.

Approval Year

PubMed

Title	Date	PubMed
Behavioral thermoregulation in the study of drugs affecting body temperature.	1975-11-01	1223894
[Paradryl salve and ido tar, two new preparations for Besnier's prurigo and eczema].	1951-11-29	14922568
Paradryl ointment and Ido tar; two new remedies for the treatment of Besnier's prurigo and eczema.	1951	14894074

Substance Class	Chemical Created by `admin` on `Mon Mar 31 19:30:33 GMT 2025` Edited by `admin` on `Mon Mar 31 19:30:33 GMT 2025`
Record UNII	UJO67AO8YI
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

MEFENIDRAMIUM BROMIDE

Common Name

English

DIPHENHYDRAMINE METHYLBROMIDE

Preferred Name

English

ETHANAMINIUM, 2-(DIPHENYLMETHOXY)-N,N,N-TRIMETHYL-, BROMIDE (1:1)

Systematic Name

English

Mefenidramium bromide [WHO-DD]

Common Name

English

PARADRYL

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C267