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Details

Stereochemistry RACEMIC
Molecular Formula C17H27N.C6H8O7
Molecular Weight 437.5274
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of GAMFEXINE CITRATE

SMILES

CN(C)CCC(c1ccccc1)C2CCCCC2.C(C(=O)O)C(CC(=O)O)(C(=O)O)O

InChI

InChIKey=SGKRLANBLXKJAB-UHFFFAOYSA-N
InChI=1S/C17H27N.C6H8O7/c1-18(2)14-13-17(15-9-5-3-6-10-15)16-11-7-4-8-12-16;7-3(8)1-6(13,5(11)12)2-4(9)10/h3,5-6,9-10,16-17H,4,7-8,11-14H2,1-2H3;13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)

HIDE SMILES / InChI

Molecular Formula C6H8O7
Molecular Weight 192.1238
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula C17H27N
Molecular Weight 245.4036
Charge 0
Count
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 0
Optical Activity ( + / - )

Description
Curator's Comment:: 3 Pubmed ID's, but are title only

Gamfexine (WIN 1344) was introduced in the literature in 1966 as an anti-depressant. Although it was reported to be effective in the treatment of withdrawal in schizophrenia, it worsened psychotic symptoms.

Approval Year

PubMed

PubMed

TitleDatePubMed
A controlled study of the effects of gamfexine in phenothiazine-treated patients.
1970 Apr
Substance Class Chemical
Created
by admin
on Sat Jun 26 03:29:05 UTC 2021
Edited
by admin
on Sat Jun 26 03:29:05 UTC 2021
Record UNII
659LD8KI7Z
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
GAMFEXINE CITRATE
Common Name English
N,N-DIMETHYL-.GAMMA.-PHENYLCYCLOHEXANEPROPYLAMINE CITRATE SALT
Systematic Name English
BENZENEPROPANAMINE, .GAMMA.-CYCLOHEXYL-N,N-DIMETHYL-, 2-HYDROXY-1,2,3-PROPANETRICARBOXYLATE (1:1)
Systematic Name English
Code System Code Type Description
FDA UNII
659LD8KI7Z
Created by admin on Sat Jun 26 03:29:06 UTC 2021 , Edited by admin on Sat Jun 26 03:29:06 UTC 2021
PRIMARY
CAS
22202-77-3
Created by admin on Sat Jun 26 03:29:06 UTC 2021 , Edited by admin on Sat Jun 26 03:29:06 UTC 2021
PRIMARY
PUBCHEM
23619748
Created by admin on Sat Jun 26 03:29:06 UTC 2021 , Edited by admin on Sat Jun 26 03:29:06 UTC 2021
PRIMARY
Related Record Type Details
ENANTIOMER -> RACEMATE
PARENT -> SALT/SOLVATE
PARENT -> SALT/SOLVATE
ENANTIOMER -> RACEMATE
Related Record Type Details
ACTIVE MOIETY