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Details

Stereochemistry RACEMIC
Molecular Formula C17H27N
Molecular Weight 245.4036
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of GAMFEXINE

SMILES

CN(C)CCC(c1ccccc1)C2CCCCC2

InChI

InChIKey=AJDSHXKJJDQZCJ-UHFFFAOYSA-N
InChI=1S/C17H27N/c1-18(2)14-13-17(15-9-5-3-6-10-15)16-11-7-4-8-12-16/h3,5-6,9-10,16-17H,4,7-8,11-14H2,1-2H3

HIDE SMILES / InChI

Molecular Formula C17H27N
Molecular Weight 245.4036
Charge 0
Count
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 0
Optical Activity ( + / - )

Description
Curator's Comment:: 3 Pubmed ID's, but are title only

Gamfexine (WIN 1344) was introduced in the literature in 1966 as an anti-depressant. Although it was reported to be effective in the treatment of withdrawal in schizophrenia, it worsened psychotic symptoms.

Approval Year

PubMed

PubMed

TitleDatePubMed
Preclinical-clinical correlation of anti-depressant activity: controlled study of gamfexine and imipramine.
1967 Jul
A controlled study of the effects of gamfexine in phenothiazine-treated patients.
1970 Apr
Substance Class Chemical
Created
by admin
on Sat Jun 26 16:26:42 UTC 2021
Edited
by admin
on Sat Jun 26 16:26:42 UTC 2021
Record UNII
3U2V80KPAL
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
GAMFEXINE
INN   USAN  
USAN   INN  
Official Name English
WIN-1344
Code English
GAMFEXINE [INN]
Common Name English
N,N-DIMETHYL-.GAMMA.-PHENYLCYCLOHEXANEPROPYLAMINE
Systematic Name English
WIN 1344
Code English
GAMFEXINE [USAN]
Common Name English
BENZENEPROPANAMINE, .GAMMA.-CYCLOHEXYL-N,N-DIMETHYL-
Systematic Name English
Code System Code Type Description
NCI_THESAURUS
C166697
Created by admin on Sat Jun 26 16:26:42 UTC 2021 , Edited by admin on Sat Jun 26 16:26:42 UTC 2021
PRIMARY
EVMPD
SUB07878MIG
Created by admin on Sat Jun 26 16:26:42 UTC 2021 , Edited by admin on Sat Jun 26 16:26:42 UTC 2021
PRIMARY
INN
2225
Created by admin on Sat Jun 26 16:26:42 UTC 2021 , Edited by admin on Sat Jun 26 16:26:42 UTC 2021
PRIMARY
FDA UNII
3U2V80KPAL
Created by admin on Sat Jun 26 16:26:42 UTC 2021 , Edited by admin on Sat Jun 26 16:26:42 UTC 2021
PRIMARY
ChEMBL
CHEMBL2106747
Created by admin on Sat Jun 26 16:26:42 UTC 2021 , Edited by admin on Sat Jun 26 16:26:42 UTC 2021
PRIMARY
PUBCHEM
31041
Created by admin on Sat Jun 26 16:26:42 UTC 2021 , Edited by admin on Sat Jun 26 16:26:42 UTC 2021
PRIMARY
WIKIPEDIA
GAMFEXINE
Created by admin on Sat Jun 26 16:26:42 UTC 2021 , Edited by admin on Sat Jun 26 16:26:42 UTC 2021
PRIMARY
CAS
7273-99-6
Created by admin on Sat Jun 26 16:26:42 UTC 2021 , Edited by admin on Sat Jun 26 16:26:42 UTC 2021
PRIMARY
Related Record Type Details
ENANTIOMER -> RACEMATE
ENANTIOMER -> RACEMATE
SALT/SOLVATE -> PARENT
Related Record Type Details
ACTIVE MOIETY