Guanine

Investigational

Details

Stereochemistry	ACHIRAL
Molecular Formula	C5H5N5O
Molecular Weight	151.1261
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

NC1=NC2=C(N=CN2)C(=O)N1

InChI

InChIKey=UYTPUPDQBNUYGX-UHFFFAOYSA-N

InChI=1S/C5H5N5O/c6-5-9-3-2(4(11)10-5)7-1-8-3/h1H,(H4,6,7,8,9,10,11)

HIDE SMILES / InChI

Molecular Formula	C5H5N5O
Molecular Weight	151.1261
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Inactivation of O6-alkylguanine-DNA alkyltransferase by 8-substituted O6-benzylguanine analogs in mice.	2001	11221964
125I-Antisauvagine-30: a novel and specific high-affinity radioligand for the characterization of corticotropin-releasing factor type 2 receptors.	2001	11077077
Base sequence-specific attack of stilbene estrogen metabolite(s) on the mitochondrial DNA: implications in the induction of instability in the mitochondrial genome in the kidney of Syrian hamsters.	2001 Apr	11254879
Reduction of BCNU toxicity to lung cells by high-level expression of O(6)-methylguanine-DNA methyltransferase.	2001 Apr	11238017
Kinetic and mechanistic properties of biotin sulfoxide reductase.	2001 Feb 6	11170471
Thermodynamics of ion-induced RNA folding in the hammerhead ribozyme: an isothermal titration calorimetric study.	2001 Feb 6	11170470
Fidelity of nucleotide insertion at 8-oxo-7,8-dihydroguanine by mammalian DNA polymerase delta. Steady-state and pre-steady-state kinetic analysis.	2001 Feb 9	11110788
Guanine versus deoxyribose damage in DNA oxidation mediated by vanadium(IV) and vanadium(V) complexes.	2001 Jan	11191217
Protection and in vivo selection of hematopoietic stem cells using temozolomide, O6-benzylguanine, and an alkyltransferase-expressing retroviral vector.	2001 Jan	11162314
Genetic study of SOX9 in a case of campomelic dysplasia.	2001 Jan 15	11223854
The guanine protein coupled receptor rhodopsin is developmentally regulated in the free-living stages of Schistosoma mansoni.	2001 Jan 15	11166392
Amino acid residues in ribonuclease MC1 from bitter gourd seeds which are essential for uridine specificity.	2001 Jan 16	11148047
Structure-activity relationships in flexible protein domains: regulation of rho GTPases by RhoGDI and D4 GDI.	2001 Jan 5	11114252
New biochemical markers in Alzheimer disease.	2001 Mar	11255437
Metabolism of the beta-oxidized intermediates of N-nitrosodi-n-propylamine: N-nitroso-beta-hydroxypropylpropylamine and N-nitroso-beta-oxopropylpropylamine.	2001 Mar	11238192
Patterns of p53 G-->T transversions in lung cancers reflect the primary mutagenic signature of DNA-damage by tobacco smoke.	2001 Mar	11238174
Structure, folding and activity of the VS ribozyme: importance of the 2-3-6 helical junction.	2001 Mar 15	11250907
Rap1 is activated by erythropoietin or interleukin-3 and is involved in regulation of beta1 integrin-mediated hematopoietic cell adhesion.	2001 Mar 30	11124936
Characterization of cDNA encoding the human tRNA-guanine transglycosylase (TGT) catalytic subunit.	2001 Mar 7	11255023
The Drosophila S3 multifunctional DNA repair/ribosomal protein protects Fanconi anemia cells against oxidative DNA damaging agents.	2001 Mar 7	11182542

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:22:18 GMT 2025` Edited by `admin` on `Mon Mar 31 18:22:18 GMT 2025`
Record UNII	5Z93L87A1R
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

CI 75170

Preferred Name

English

Guanine

Official Name

English

GUANINE [EP IMPURITY]

Common Name

English

2-AMINOHYPOXANTHINE

Common Name

English

2-AMINO-1,7-DIHYDRO-6H-PURIN-6-ONE [WHO-IP]

Systematic Name

English

GANCICLOVIR IMPURITY F [EP IMPURITY]

Common Name

English

C.I. NO. 75170 (GUANINE)

Common Name

English

6H-PURIN-6-ONE, 2-AMINO-1,7-DIHYDRO-

Systematic Name

English

VALGANCICLOVIR HYDROCHLORIDE IMPURITY B [USP IMPURITY]

Common Name

English

GUANINE [USP IMPURITY]

Common Name

English

VALACICLOVIR HYDROCHLORIDE HYDRATE IMPURITY A [EP IMPURITY]

Common Name

English

ACICLOVIR IMPURITY B [EP IMPURITY]

Common Name

English

GUANINE [WHO-IP]

Common Name

English

GUANINE [USP-RS]

Common Name

English

GUANINE [HSDB]

Common Name

English

ACICLOVIR IMPURITY B [WHO-IP]

Common Name

English

GUANINE [MI]

Common Name

English

VALACICLOVIR HYDROCHLORIDE IMPURITY A [EP IMPURITY]

Common Name

English

Classification Tree Code System Code

LOINC

78695-4