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Details

Stereochemistry ACHIRAL
Molecular Formula C5H5N5O
Molecular Weight 151.1261
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of Guanine

SMILES

NC1=NC2=C(N=CN2)C(=O)N1

InChI

InChIKey=UYTPUPDQBNUYGX-UHFFFAOYSA-N
InChI=1S/C5H5N5O/c6-5-9-3-2(4(11)10-5)7-1-8-3/h1H,(H4,6,7,8,9,10,11)

HIDE SMILES / InChI

Molecular Formula C5H5N5O
Molecular Weight 151.1261
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Inactivation of O6-alkylguanine-DNA alkyltransferase by 8-substituted O6-benzylguanine analogs in mice.
2001
125I-Antisauvagine-30: a novel and specific high-affinity radioligand for the characterization of corticotropin-releasing factor type 2 receptors.
2001
Base sequence-specific attack of stilbene estrogen metabolite(s) on the mitochondrial DNA: implications in the induction of instability in the mitochondrial genome in the kidney of Syrian hamsters.
2001 Apr
Reduction of BCNU toxicity to lung cells by high-level expression of O(6)-methylguanine-DNA methyltransferase.
2001 Apr
Kinetic and mechanistic properties of biotin sulfoxide reductase.
2001 Feb 6
Thermodynamics of ion-induced RNA folding in the hammerhead ribozyme: an isothermal titration calorimetric study.
2001 Feb 6
Fidelity of nucleotide insertion at 8-oxo-7,8-dihydroguanine by mammalian DNA polymerase delta. Steady-state and pre-steady-state kinetic analysis.
2001 Feb 9
Guanine versus deoxyribose damage in DNA oxidation mediated by vanadium(IV) and vanadium(V) complexes.
2001 Jan
Protection and in vivo selection of hematopoietic stem cells using temozolomide, O6-benzylguanine, and an alkyltransferase-expressing retroviral vector.
2001 Jan
Genetic study of SOX9 in a case of campomelic dysplasia.
2001 Jan 15
The guanine protein coupled receptor rhodopsin is developmentally regulated in the free-living stages of Schistosoma mansoni.
2001 Jan 15
Amino acid residues in ribonuclease MC1 from bitter gourd seeds which are essential for uridine specificity.
2001 Jan 16
Structure-activity relationships in flexible protein domains: regulation of rho GTPases by RhoGDI and D4 GDI.
2001 Jan 5
New biochemical markers in Alzheimer disease.
2001 Mar
Metabolism of the beta-oxidized intermediates of N-nitrosodi-n-propylamine: N-nitroso-beta-hydroxypropylpropylamine and N-nitroso-beta-oxopropylpropylamine.
2001 Mar
Patterns of p53 G-->T transversions in lung cancers reflect the primary mutagenic signature of DNA-damage by tobacco smoke.
2001 Mar
Structure, folding and activity of the VS ribozyme: importance of the 2-3-6 helical junction.
2001 Mar 15
Rap1 is activated by erythropoietin or interleukin-3 and is involved in regulation of beta1 integrin-mediated hematopoietic cell adhesion.
2001 Mar 30
Characterization of cDNA encoding the human tRNA-guanine transglycosylase (TGT) catalytic subunit.
2001 Mar 7
The Drosophila S3 multifunctional DNA repair/ribosomal protein protects Fanconi anemia cells against oxidative DNA damaging agents.
2001 Mar 7
Patents
Substance Class Chemical
Created
by admin
on Mon Mar 31 18:22:18 GMT 2025
Edited
by admin
on Mon Mar 31 18:22:18 GMT 2025
Record UNII
5Z93L87A1R
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
CI 75170
INCI  
INCI  
Preferred Name English
Guanine
HSDB   INCI   MI   USP-RS  
INCI  
Official Name English
GUANINE [EP IMPURITY]
Common Name English
2-AMINOHYPOXANTHINE
Common Name English
2-AMINO-1,7-DIHYDRO-6H-PURIN-6-ONE [WHO-IP]
Systematic Name English
GANCICLOVIR IMPURITY F [EP IMPURITY]
Common Name English
C.I. NO. 75170 (GUANINE)
Common Name English
6H-PURIN-6-ONE, 2-AMINO-1,7-DIHYDRO-
Systematic Name English
VALGANCICLOVIR HYDROCHLORIDE IMPURITY B [USP IMPURITY]
Common Name English
GUANINE [USP IMPURITY]
Common Name English
VALACICLOVIR HYDROCHLORIDE HYDRATE IMPURITY A [EP IMPURITY]
Common Name English
ACICLOVIR IMPURITY B [EP IMPURITY]
Common Name English
GUANINE [WHO-IP]
Common Name English
GUANINE [USP-RS]
Common Name English
GUANINE [HSDB]
Common Name English
ACICLOVIR IMPURITY B [WHO-IP]
Common Name English
GUANINE [MI]
Common Name English
VALACICLOVIR HYDROCHLORIDE IMPURITY A [EP IMPURITY]
Common Name English
Classification Tree Code System Code
LOINC 78695-4
Created by admin on Mon Mar 31 18:22:18 GMT 2025 , Edited by admin on Mon Mar 31 18:22:18 GMT 2025
NCI_THESAURUS C786
Created by admin on Mon Mar 31 18:22:18 GMT 2025 , Edited by admin on Mon Mar 31 18:22:18 GMT 2025
LOINC 79690-4
Created by admin on Mon Mar 31 18:22:18 GMT 2025 , Edited by admin on Mon Mar 31 18:22:18 GMT 2025
LOINC 79663-1
Created by admin on Mon Mar 31 18:22:18 GMT 2025 , Edited by admin on Mon Mar 31 18:22:18 GMT 2025
Code System Code Type Description
MERCK INDEX
m5869
Created by admin on Mon Mar 31 18:22:18 GMT 2025 , Edited by admin on Mon Mar 31 18:22:18 GMT 2025
PRIMARY Merck Index
DRUG BANK
DB02377
Created by admin on Mon Mar 31 18:22:18 GMT 2025 , Edited by admin on Mon Mar 31 18:22:18 GMT 2025
PRIMARY
CAS
73-40-5
Created by admin on Mon Mar 31 18:22:18 GMT 2025 , Edited by admin on Mon Mar 31 18:22:18 GMT 2025
PRIMARY
HSDB
2127
Created by admin on Mon Mar 31 18:22:18 GMT 2025 , Edited by admin on Mon Mar 31 18:22:18 GMT 2025
PRIMARY
RS_ITEM_NUM
1302156
Created by admin on Mon Mar 31 18:22:18 GMT 2025 , Edited by admin on Mon Mar 31 18:22:18 GMT 2025
PRIMARY
FDA UNII
5Z93L87A1R
Created by admin on Mon Mar 31 18:22:18 GMT 2025 , Edited by admin on Mon Mar 31 18:22:18 GMT 2025
PRIMARY
MESH
D006147
Created by admin on Mon Mar 31 18:22:18 GMT 2025 , Edited by admin on Mon Mar 31 18:22:18 GMT 2025
PRIMARY
PUBCHEM
135398634
Created by admin on Mon Mar 31 18:22:18 GMT 2025 , Edited by admin on Mon Mar 31 18:22:18 GMT 2025
PRIMARY
RXCUI
1372539
Created by admin on Mon Mar 31 18:22:18 GMT 2025 , Edited by admin on Mon Mar 31 18:22:18 GMT 2025
PRIMARY RxNorm
WIKIPEDIA
GUANINE
Created by admin on Mon Mar 31 18:22:18 GMT 2025 , Edited by admin on Mon Mar 31 18:22:18 GMT 2025
PRIMARY
SMS_ID
100000182768
Created by admin on Mon Mar 31 18:22:18 GMT 2025 , Edited by admin on Mon Mar 31 18:22:18 GMT 2025
PRIMARY
EPA CompTox
DTXSID9052476
Created by admin on Mon Mar 31 18:22:18 GMT 2025 , Edited by admin on Mon Mar 31 18:22:18 GMT 2025
PRIMARY
CHEBI
16235
Created by admin on Mon Mar 31 18:22:18 GMT 2025 , Edited by admin on Mon Mar 31 18:22:18 GMT 2025
PRIMARY
NCI_THESAURUS
C532
Created by admin on Mon Mar 31 18:22:18 GMT 2025 , Edited by admin on Mon Mar 31 18:22:18 GMT 2025
PRIMARY
ECHA (EC/EINECS)
200-799-8
Created by admin on Mon Mar 31 18:22:18 GMT 2025 , Edited by admin on Mon Mar 31 18:22:18 GMT 2025
PRIMARY
Related Record Type Details
DERIVATIVE -> PARENT
Related Record Type Details
PARENT -> METABOLITE
Related Record Type Details
PARENT -> IMPURITY
sum of impurities A and B: maximum 2.0 per cent
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
PARENT -> IMPURITY
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
PARENT -> IMPURITY
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
PARENT -> IMPURITY
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
PARENT -> IMPURITY
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
PARENT -> IMPURITY
sum of impurities A and B: maximum 2.0 per cent
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
PARENT -> IMPURITY
CHROMATOGRAPHIC PURITY (HPLC/UV)
INTERNATIONAL PHARMACOPEIA
Related Record Type Details
ACTIVE MOIETY