ASPARAGINE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C4H8N2O3
Molecular Weight	132.1179
Optical Activity	UNSPECIFIED
Defined Stereocenters	1 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of ASPARAGINE

Structure Search

SMILES

N[C@@H](CC(N)=O)C(O)=O

InChI

InChIKey=DCXYFEDJOCDNAF-REOHCLBHSA-N

InChI=1S/C4H8N2O3/c5-2(4(8)9)1-3(6)7/h2H,1,5H2,(H2,6,7)(H,8,9)/t2-/m0/s1

HIDE SMILES / InChI

Molecular Formula	C4H8N2O3
Molecular Weight	132.1179
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	1 / 1
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/12790521 | http://www.sciencedirect.com/topics/neuroscience/asparagine

Asparagine is a non-essential amino acid, which is synthesized in the human body from L-aspartate by Asparagine synthetase. Asparagine is required for the synthesis of many important cellular proteins in normal human cells. Many tumor cells do not have this capacity, due to a lack of the enzyme L-asparagine synthetase, and therefore require an exogenous supply of the amino acid. This amino acid participates in the functions of the brain and nervous system. Asparagine may come from food or be taken as a dietary supplement.

Originator

Approval Year

Conditions

Conditions

Condition	Modality	Targets	Highest Phase	Product
Unknown 2578

PubMed

PubMed

Title	Date	PubMed
Asparagine in blood plasma.	1953 Jun 20	13072518
Diminished phenylketonuria in phenylpyruvic oligophrenia after administration of L-glutamine, L-glutamate or L-asparagine.	1956 Jun	13319499
L-asparaginase and L-asparagine metabolism.	1970	4911021
Mass spectrometric analysis of asparagine deamidation and aspartate isomerization in polypeptides.	2010 Jun	20446295

Patents

Patents

Sample Use Guides

In Vivo Use Guide

500 mg or 1 capsule daily as a dietary supplement or as recommended by a healthcare practitioner.

Route of Administration: Oral

In Vitro Use Guide

HeLa cells were treated with 0.1 mM asparagine and at this concentration, the amino acid promoted cancer cell proliferation in 3 times.

Substance Class	Chemical Created by `admin` on `Sat Dec 16 05:43:15 UTC 2023` Edited by `admin` on `Sat Dec 16 05:43:15 UTC 2023`
Record UNII	5Z33R5TKO7
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

ASPARAGINE

Official Name

English

L-ASPARAGINE [FCC]

Common Name

English

Asparagine [WHO-DD]

Common Name

English

ASPARAGINE [INCI]

Common Name

English

ASPARAGINE [MI]

Common Name

English

L-ASPARAGINE

Systematic Name

English

ASPARAGINE ANHYDROUS [USP-RS]

Common Name

English

ASPARAGINE ANHYDROUS

Common Name

English

ASPARAGINE [HSDB]

Common Name

English

L-ASPARAGINE ANHYDROUS

Common Name

English

ASPARAGINE, L-

Systematic Name

English

(S)-2,4-DIAMINO-4-OXOBUTANOIC ACID

Systematic Name

English

NSC-82391

Code

English

7NG0A2TUHQ

Common Name

English

Classification Tree Code System Code

LOINC

25326-0

Created by admin on Sat Dec 16 05:43:15 UTC 2023 , Edited by admin on Sat Dec 16 05:43:15 UTC 2023

LOINC

1910-9

Created by admin on Sat Dec 16 05:43:15 UTC 2023 , Edited by admin on Sat Dec 16 05:43:15 UTC 2023

LOINC

53395-0

Created by admin on Sat Dec 16 05:43:15 UTC 2023 , Edited by admin on Sat Dec 16 05:43:15 UTC 2023

LOINC

26603-1

Created by admin on Sat Dec 16 05:43:15 UTC 2023 , Edited by admin on Sat Dec 16 05:43:15 UTC 2023

LOINC

1907-5

Created by admin on Sat Dec 16 05:43:15 UTC 2023 , Edited by admin on Sat Dec 16 05:43:15 UTC 2023

LOINC

13388-4

Created by admin on Sat Dec 16 05:43:15 UTC 2023 , Edited by admin on Sat Dec 16 05:43:15 UTC 2023

LOINC

53155-8

Created by admin on Sat Dec 16 05:43:15 UTC 2023 , Edited by admin on Sat Dec 16 05:43:15 UTC 2023

LOINC

47572-3

Created by admin on Sat Dec 16 05:43:15 UTC 2023 , Edited by admin on Sat Dec 16 05:43:15 UTC 2023

LOINC

44301-0

Created by admin on Sat Dec 16 05:43:15 UTC 2023 , Edited by admin on Sat Dec 16 05:43:15 UTC 2023

LOINC

25863-2

Created by admin on Sat Dec 16 05:43:15 UTC 2023 , Edited by admin on Sat Dec 16 05:43:15 UTC 2023

LOINC

1909-1

Created by admin on Sat Dec 16 05:43:15 UTC 2023 , Edited by admin on Sat Dec 16 05:43:15 UTC 2023

LOINC

56643-0

Created by admin on Sat Dec 16 05:43:15 UTC 2023 , Edited by admin on Sat Dec 16 05:43:15 UTC 2023

LOINC

28603-9

Created by admin on Sat Dec 16 05:43:15 UTC 2023 , Edited by admin on Sat Dec 16 05:43:15 UTC 2023

LOINC

27995-0

Created by admin on Sat Dec 16 05:43:15 UTC 2023 , Edited by admin on Sat Dec 16 05:43:15 UTC 2023

LOINC

1908-3

Created by admin on Sat Dec 16 05:43:15 UTC 2023 , Edited by admin on Sat Dec 16 05:43:15 UTC 2023

LOINC

53505-4

Created by admin on Sat Dec 16 05:43:15 UTC 2023 , Edited by admin on Sat Dec 16 05:43:15 UTC 2023

LOINC

25862-4

Created by admin on Sat Dec 16 05:43:15 UTC 2023 , Edited by admin on Sat Dec 16 05:43:15 UTC 2023

LOINC

16410-3

Created by admin on Sat Dec 16 05:43:15 UTC 2023 , Edited by admin on Sat Dec 16 05:43:15 UTC 2023

DSLD

4055 (Number of products:18)

Created by admin on Sat Dec 16 05:43:15 UTC 2023 , Edited by admin on Sat Dec 16 05:43:15 UTC 2023

LOINC

26577-7

Created by admin on Sat Dec 16 05:43:15 UTC 2023 , Edited by admin on Sat Dec 16 05:43:15 UTC 2023

LOINC

32230-5

Created by admin on Sat Dec 16 05:43:15 UTC 2023 , Edited by admin on Sat Dec 16 05:43:15 UTC 2023

LOINC

53396-8

Created by admin on Sat Dec 16 05:43:15 UTC 2023 , Edited by admin on Sat Dec 16 05:43:15 UTC 2023

LOINC

27089-2

Created by admin on Sat Dec 16 05:43:15 UTC 2023 , Edited by admin on Sat Dec 16 05:43:15 UTC 2023

CFR

21 CFR 172.320

Created by admin on Sat Dec 16 05:43:15 UTC 2023 , Edited by admin on Sat Dec 16 05:43:15 UTC 2023

LOINC

27317-7

Created by admin on Sat Dec 16 05:43:15 UTC 2023 , Edited by admin on Sat Dec 16 05:43:15 UTC 2023

NCI_THESAURUS

C29596

Created by admin on Sat Dec 16 05:43:15 UTC 2023 , Edited by admin on Sat Dec 16 05:43:15 UTC 2023

LOINC

1906-7

Created by admin on Sat Dec 16 05:43:15 UTC 2023 , Edited by admin on Sat Dec 16 05:43:15 UTC 2023

NCI_THESAURUS

C68442

Created by admin on Sat Dec 16 05:43:15 UTC 2023 , Edited by admin on Sat Dec 16 05:43:15 UTC 2023

LOINC

13710-9

Created by admin on Sat Dec 16 05:43:15 UTC 2023 , Edited by admin on Sat Dec 16 05:43:15 UTC 2023

LOINC

20638-3

Created by admin on Sat Dec 16 05:43:15 UTC 2023 , Edited by admin on Sat Dec 16 05:43:15 UTC 2023

Code System Code Type Description

ECHA (EC/EINECS)

200-735-9

Created by admin on Sat Dec 16 05:43:15 UTC 2023 , Edited by admin on Sat Dec 16 05:43:15 UTC 2023

PRIMARY

CHEBI

58048

Created by admin on Sat Dec 16 05:43:15 UTC 2023 , Edited by admin on Sat Dec 16 05:43:15 UTC 2023

PRIMARY

WIKIPEDIA

ASPARAGINE

Created by admin on Sat Dec 16 05:43:15 UTC 2023 , Edited by admin on Sat Dec 16 05:43:15 UTC 2023

PRIMARY

CHEBI

50348

Created by admin on Sat Dec 16 05:43:15 UTC 2023 , Edited by admin on Sat Dec 16 05:43:15 UTC 2023

PRIMARY

MESH

D001216

Created by admin on Sat Dec 16 05:43:15 UTC 2023 , Edited by admin on Sat Dec 16 05:43:15 UTC 2023

PRIMARY

NCI_THESAURUS

C29607

Created by admin on Sat Dec 16 05:43:15 UTC 2023 , Edited by admin on Sat Dec 16 05:43:15 UTC 2023

PRIMARY

DRUG CENTRAL

4126

Created by admin on Sat Dec 16 05:43:15 UTC 2023 , Edited by admin on Sat Dec 16 05:43:15 UTC 2023

PRIMARY

ChEMBL

CHEMBL58832

Created by admin on Sat Dec 16 05:43:15 UTC 2023 , Edited by admin on Sat Dec 16 05:43:15 UTC 2023

PRIMARY

EVMPD

SUB12951MIG

Created by admin on Sat Dec 16 05:43:15 UTC 2023 , Edited by admin on Sat Dec 16 05:43:15 UTC 2023

PRIMARY

NCI_THESAURUS

C1505

Created by admin on Sat Dec 16 05:43:15 UTC 2023 , Edited by admin on Sat Dec 16 05:43:15 UTC 2023

CONCEPT

Dietary Supplement

CHEBI

22653

Created by admin on Sat Dec 16 05:43:15 UTC 2023 , Edited by admin on Sat Dec 16 05:43:15 UTC 2023

PRIMARY

NSC

82391

Created by admin on Sat Dec 16 05:43:15 UTC 2023 , Edited by admin on Sat Dec 16 05:43:15 UTC 2023

PRIMARY

CAS

70-47-3

Created by admin on Sat Dec 16 05:43:15 UTC 2023 , Edited by admin on Sat Dec 16 05:43:15 UTC 2023

PRIMARY

DAILYMED

5Z33R5TKO7

Created by admin on Sat Dec 16 05:43:15 UTC 2023 , Edited by admin on Sat Dec 16 05:43:15 UTC 2023

PRIMARY

FDA UNII

5Z33R5TKO7

Created by admin on Sat Dec 16 05:43:15 UTC 2023 , Edited by admin on Sat Dec 16 05:43:15 UTC 2023

PRIMARY

CHEBI

17196

Created by admin on Sat Dec 16 05:43:15 UTC 2023 , Edited by admin on Sat Dec 16 05:43:15 UTC 2023

PRIMARY

CHEBI

50347

Created by admin on Sat Dec 16 05:43:15 UTC 2023 , Edited by admin on Sat Dec 16 05:43:15 UTC 2023

PRIMARY

RS_ITEM_NUM

1043502

Created by admin on Sat Dec 16 05:43:15 UTC 2023 , Edited by admin on Sat Dec 16 05:43:15 UTC 2023

PRIMARY

DRUG BANK

DB00174

Created by admin on Sat Dec 16 05:43:15 UTC 2023 , Edited by admin on Sat Dec 16 05:43:15 UTC 2023

PRIMARY

PUBCHEM

6267

Created by admin on Sat Dec 16 05:43:15 UTC 2023 , Edited by admin on Sat Dec 16 05:43:15 UTC 2023

PRIMARY

RXCUI

1157

Created by admin on Sat Dec 16 05:43:15 UTC 2023 , Edited by admin on Sat Dec 16 05:43:15 UTC 2023

PRIMARY

RxNorm

EPA CompTox

DTXSID10883220

Created by admin on Sat Dec 16 05:43:15 UTC 2023 , Edited by admin on Sat Dec 16 05:43:15 UTC 2023

PRIMARY

SMS_ID

100000077458

Created by admin on Sat Dec 16 05:43:15 UTC 2023 , Edited by admin on Sat Dec 16 05:43:15 UTC 2023

PRIMARY

MERCK INDEX

m2097

Created by admin on Sat Dec 16 05:43:15 UTC 2023 , Edited by admin on Sat Dec 16 05:43:15 UTC 2023

SUPERSEDED

HSDB

7425

Created by admin on Sat Dec 16 05:43:15 UTC 2023 , Edited by admin on Sat Dec 16 05:43:15 UTC 2023

PRIMARY

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SALT/SOLVATE -> PARENT

Amount:


					2PD79VF521

ASPARAGINE MONOHYDRATE

SALT/SOLVATE -> PARENT

Amount:


					2PD79VF521

ASPARAGINE MONOHYDRATE

SOLVATE->ANHYDROUS

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