OXSI-2

Details

Stereochemistry	ACHIRAL
Molecular Formula	C18H15N3O3S
Molecular Weight	353.395
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CN1C=C(\C=C2/C(=O)NC3=C2C=C(C=C3)S(N)(=O)=O)C4=C1C=CC=C4

InChI

InChIKey=MLKHXLFEYOOYEY-NVNXTCNLSA-N

InChI=1S/C18H15N3O3S/c1-21-10-11(13-4-2-3-5-17(13)21)8-15-14-9-12(25(19,23)24)6-7-16(14)20-18(15)22/h2-10H,1H3,(H,20,22)(H2,19,23,24)/b15-8-

HIDE SMILES / InChI

Molecular Formula	C18H15N3O3S
Molecular Weight	353.395
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	1
Optical Activity	NONE

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Tyrosine-protein kinase SYK 21 Target ID: CHEMBL2599 Sources: https://www.ncbi.nlm.nih.gov/pubmed/12941345 \| https://www.ncbi.nlm.nih.gov/pubmed/22257213	Inhibitor 8297		14.0 nM [IC50]

PubMed

Title	Date	PubMed

Substance Class	Chemical Created by `admin` on `Sat Dec 16 11:08:21 UTC 2023` Edited by `admin` on `Sat Dec 16 11:08:21 UTC 2023`
Record UNII	5YZ3QBQ97C
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

OXSI-2

Code

English

SYK INHIBITOR

Common Name

English

K00564A

Code

English

CG-103065

Code

English

SPLEEN TYROSINE KINASE INHIBITOR

Common Name

English

1H-INDOLE-5-SULFONAMIDE, 2,3-DIHYDRO-3-((1-METHYL-1H-INDOL-3-YL)METHYLENE)-2-OXO-

Systematic Name

English

2,3-DIHYDRO-3-((1-METHYL-1H-INDOL-3-YL)METHYLENE)-2-OXO-1H-INDOLE-5-SULFONAMIDE

Systematic Name

English

1H-INDOLE-5-SULFONAMIDE, 2,3-DIHYDRO-3-((1-METHYL-1H-INDOL-3-YL)METHYLENE)-2-OXO-, (3Z)-

Systematic Name

English

Code System Code Type Description

CHEBI

76617