U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Jun 26 17:23:26 UTC 2021
Edited
by admin
on Sat Jun 26 17:23:26 UTC 2021
Protein Sub Type
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
JS20X60RRY
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
TYROSINE-PROTEIN KINASE SYK
Common Name English
SPLEEN TYROSINE KINASE
Common Name English
SYK
Common Name English
P72-SYK
Common Name English
Code System Code Type Description
WIKIPEDIA
SYK
Created by admin on Sat Jun 26 17:23:27 UTC 2021 , Edited by admin on Sat Jun 26 17:23:27 UTC 2021
PRIMARY
UNIPROT
P43405
Created by admin on Sat Jun 26 17:23:27 UTC 2021 , Edited by admin on Sat Jun 26 17:23:27 UTC 2021
PRIMARY
FDA UNII
JS20X60RRY
Created by admin on Sat Jun 26 17:23:27 UTC 2021 , Edited by admin on Sat Jun 26 17:23:27 UTC 2021
PRIMARY
PHAROS
P43405
Created by admin on Sat Jun 26 17:23:27 UTC 2021 , Edited by admin on Sat Jun 26 17:23:27 UTC 2021
PRIMARY
Related Record Type Details
INHIBITOR -> TARGET
IC50
INHIBITOR -> TARGET
IC50
INHIBITOR -> TARGET
INHIBITOR -> TARGET
Assessed by Invitrogen/Life Technologies using the Z’-LYTE assay format
REVERSIBLE
IC50
INHIBITOR -> TARGET
INHIBITOR -> TARGET
inhibited its kinase activity as an ATP-competitive inhibitor (Ki = 30 nM)
COMPETITIVE INHIBITOR
Ki
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
IC50
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT CHEMICAL
Molecular Formula CHEMICAL