U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C15H17NO3
Molecular Weight 259.3004
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 1
Charge 0

SHOW SMILES / InChI
Structure of ILEPCIMIDE

SMILES

O=C(\C=C\C1=CC=C2OCOC2=C1)N3CCCCC3

InChI

InChIKey=BLPUOQGPBJPXRL-FNORWQNLSA-N
InChI=1S/C15H17NO3/c17-15(16-8-2-1-3-9-16)7-5-12-4-6-13-14(10-12)19-11-18-13/h4-7,10H,1-3,8-9,11H2/b7-5+

HIDE SMILES / InChI

Molecular Formula C15H17NO3
Molecular Weight 259.3004
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 1
Optical Activity NONE

Ilepcimide, a piperine derivative, was studied in China as an anticonvulsant agent for the treatment of seizures in epilepsy children patients. However, this study was discontinued.

Approval Year

PubMed

PubMed

TitleDatePubMed
[Effect of Ilepcimide Combined Western Drugs on Serum Level of Neuron Specific Enolase in Treating Epilepsy Children Patients].
2016 Aug

Sample Use Guides

5 mg/kg per day as initial dose, taken in two times
Route of Administration: Oral
Substance Class Chemical
Created
by admin
on Sat Dec 16 17:02:03 GMT 2023
Edited
by admin
on Sat Dec 16 17:02:03 GMT 2023
Record UNII
5ML58O200F
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ILEPCIMIDE
INN   USAN  
USAN   INN  
Official Name English
ILEPCIMIDE [USAN]
Common Name English
Ilepcimide [WHO-DD]
Common Name English
1-[(E)-3,4-(Methylenedioxy)cinnamoyl]piperidine
Systematic Name English
ilepcimide [INN]
Common Name English
PIPERIDINE, 1-(3-(1,3-BENZODIOXOL-5-YL)-1-OXO-2-PROPENYL)-, (E)-
Common Name English
ANTIEPILEPSIRINE
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C264
Created by admin on Sat Dec 16 17:02:03 GMT 2023 , Edited by admin on Sat Dec 16 17:02:03 GMT 2023
FDA ORPHAN DRUG 34588
Created by admin on Sat Dec 16 17:02:03 GMT 2023 , Edited by admin on Sat Dec 16 17:02:03 GMT 2023
Code System Code Type Description
MESH
C037547
Created by admin on Sat Dec 16 17:02:03 GMT 2023 , Edited by admin on Sat Dec 16 17:02:03 GMT 2023
PRIMARY
PUBCHEM
641115
Created by admin on Sat Dec 16 17:02:03 GMT 2023 , Edited by admin on Sat Dec 16 17:02:03 GMT 2023
PRIMARY
NCI_THESAURUS
C72810
Created by admin on Sat Dec 16 17:02:03 GMT 2023 , Edited by admin on Sat Dec 16 17:02:03 GMT 2023
PRIMARY
WIKIPEDIA
ILEPCIMIDE
Created by admin on Sat Dec 16 17:02:03 GMT 2023 , Edited by admin on Sat Dec 16 17:02:03 GMT 2023
PRIMARY
USAN
FF-3
Created by admin on Sat Dec 16 17:02:03 GMT 2023 , Edited by admin on Sat Dec 16 17:02:03 GMT 2023
PRIMARY
EVMPD
SUB08130MIG
Created by admin on Sat Dec 16 17:02:03 GMT 2023 , Edited by admin on Sat Dec 16 17:02:03 GMT 2023
PRIMARY
INN
7175
Created by admin on Sat Dec 16 17:02:03 GMT 2023 , Edited by admin on Sat Dec 16 17:02:03 GMT 2023
PRIMARY
FDA UNII
5ML58O200F
Created by admin on Sat Dec 16 17:02:03 GMT 2023 , Edited by admin on Sat Dec 16 17:02:03 GMT 2023
PRIMARY
CAS
82857-82-7
Created by admin on Sat Dec 16 17:02:03 GMT 2023 , Edited by admin on Sat Dec 16 17:02:03 GMT 2023
PRIMARY
SMS_ID
100000083703
Created by admin on Sat Dec 16 17:02:03 GMT 2023 , Edited by admin on Sat Dec 16 17:02:03 GMT 2023
PRIMARY
ChEMBL
CHEMBL118478
Created by admin on Sat Dec 16 17:02:03 GMT 2023 , Edited by admin on Sat Dec 16 17:02:03 GMT 2023
PRIMARY
Related Record Type Details
TARGET -> INHIBITOR
PARENT -> DERIVATIVE
Related Record Type Details
ACTIVE MOIETY