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Details

Stereochemistry ABSOLUTE
Molecular Formula C18H23F2N5O4S2
Molecular Weight 475.533
Optical Activity UNSPECIFIED
Defined Stereocenters 2 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of AZD-5122

SMILES

C[C@@H](NC1=NC(SCC2=CC=CC(F)=C2F)=NC(NS(=O)(=O)N3CCC3)=C1)[C@@H](O)CO

InChI

InChIKey=QVKPEMXUBULFBM-RISCZKNCSA-N
InChI=1S/C18H23F2N5O4S2/c1-11(14(27)9-26)21-15-8-16(24-31(28,29)25-6-3-7-25)23-18(22-15)30-10-12-4-2-5-13(19)17(12)20/h2,4-5,8,11,14,26-27H,3,6-7,9-10H2,1H3,(H2,21,22,23,24)/t11-,14+/m1/s1

HIDE SMILES / InChI
Molecular Formula C18H23F2N5O4S2
Molecular Weight 475.533
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 2 / 2
E/Z Centers 0
Optical Activity UNSPECIFIED

Description

It is known, that SRT3109 is a ligand of CXCR2 for use in the treatment of chemokine mediated diseases and conditions. Others information is not available.

Approval Year

Unknown
149124
Targets

Targets

Primary TargetPharmacologyConditionPotency
Interacts
323
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Patents

Patents

US2010016275
1
US2015210655
1

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Wed Apr 02 12:39:59 GMT 2025
Edited
by admin
on Wed Apr 02 12:39:59 GMT 2025
Record UNII
5KT86HK4WX
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
AZD-5122
Code English
AZD5122
Preferred Name English
SRT3109
Code English
AZD 5122 [WHO-DD]
Common Name English
SRT-3109
Code English
N-(2-(((2,3-DIFLUOROPHENYL)METHYL)THIO)-6-(((1R,2R)-2,3-DIHYDROXY-1-METHYLPROPYL)AMINO)-4-PYRIMIDINYL)-1-AZETIDINESULFONAMIDE
Systematic Name English
1-AZETIDINESULFONAMIDE, N-(2-(((2,3-DIFLUOROPHENYL)METHYL)THIO)-6-(((1R,2R)-2,3-DIHYDROXY-1-METHYLPROPYL)AMINO)-4-PYRIMIDINYL)-
Systematic Name English
Code System Code Type Description
CAS
1204707-71-0
Created by admin on Wed Apr 02 12:39:59 GMT 2025 , Edited by admin on Wed Apr 02 12:39:59 GMT 2025
PRIMARY
EPA CompTox
DTXSID80659631
Created by admin on Wed Apr 02 12:39:59 GMT 2025 , Edited by admin on Wed Apr 02 12:39:59 GMT 2025
PRIMARY
PUBCHEM
44602493
Created by admin on Wed Apr 02 12:39:59 GMT 2025 , Edited by admin on Wed Apr 02 12:39:59 GMT 2025
PRIMARY
FDA UNII
5KT86HK4WX
Created by admin on Wed Apr 02 12:39:59 GMT 2025 , Edited by admin on Wed Apr 02 12:39:59 GMT 2025
PRIMARY
Related Record Type Details
C-X-C CHEMOKINE RECEPTOR TYPE 2
TARGET -> INHIBITOR
Related Record Type Details
Structure of AZD-5122
ACTIVE MOIETY
NIH
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