Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C16H18N2O2 |
| Molecular Weight | 270.3263 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
O=C(C1CC1)C2=CC=C(OCCCC3=CN=CN3)C=C2
InChI
InChIKey=ACQBHJXEAYTHCY-UHFFFAOYSA-N
InChI=1S/C16H18N2O2/c19-16(12-3-4-12)13-5-7-15(8-6-13)20-9-1-2-14-10-17-11-18-14/h5-8,10-12H,1-4,9H2,(H,17,18)
| Molecular Formula | C16H18N2O2 |
| Molecular Weight | 270.3263 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Effect of BP 2.94, a histamine H3-receptor agonist prodrug, on different models of colitis. | 2002 Apr |
|
| Acute and chronic effects of methamphetamine on tele-methylhistamine levels in mouse brain: selective involvement of the D(2) and not D(3) receptor. | 2002 Feb |
|
| Endogenous histamine in the medial septum-diagonal band complex increases the release of acetylcholine from the hippocampus: a dual-probe microdialysis study in the freely moving rat. | 2002 May |
|
| Coordination of histamine H3 receptor antagonists with human adrenal cytochrome P450 enzymes. | 2002 Nov |
|
| Characteristics of recombinantly expressed rat and human histamine H3 receptors. | 2002 Oct 18 |
|
| Ligands for histamine H(3) receptors modulate cell proliferation and migration in rat oxyntic mucosa. | 2002 Sep |
|
| Anatomical, physiological, and pharmacological characteristics of histidine decarboxylase knock-out mice: evidence for the role of brain histamine in behavioral and sleep-wake control. | 2002 Sep 1 |
|
| Ciproxifan, a histamine H3-receptor antagonist/inverse agonist, modulates the effects of methamphetamine on neuropeptide mRNA expression in rat striatum. | 2003 Jan |
|
| A robust and high-capacity [(35)S]GTPgammaS binding assay for determining antagonist and inverse agonist pharmacological parameters of histamine H(3) receptor ligands. | 2008 Jun |
|
| Involvement of histaminergic receptor mechanisms in the stimulation of NT-3 synthesis in astrocytes. | 2011 Jun |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 09:52:44 GMT 2023
by
admin
on
Sat Dec 16 09:52:44 GMT 2023
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| Record UNII |
5EVQ7IRG99
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| Record Status |
Validated (UNII)
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| Record Version |
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6422124
Created by
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DTXSID50171532
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184025-18-1
Created by
admin on Sat Dec 16 09:52:44 GMT 2023 , Edited by admin on Sat Dec 16 09:52:44 GMT 2023
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5EVQ7IRG99
Created by
admin on Sat Dec 16 09:52:44 GMT 2023 , Edited by admin on Sat Dec 16 09:52:44 GMT 2023
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CIPROXIFAN
Created by
admin on Sat Dec 16 09:52:44 GMT 2023 , Edited by admin on Sat Dec 16 09:52:44 GMT 2023
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ACTIVE MOIETY |
