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Approval Year

Unknown
139594
Substance Class Protein
Created
by admin
on Sat Dec 16 14:49:01 GMT 2023
Edited
by admin
on Sat Dec 16 14:49:01 GMT 2023
Protein Type RECEPTOR
Protein Sub Type
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
D9SCP0G3HF
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
HISTAMINE H3 RECEPTOR
Common Name English
GPCR97
Common Name English
G-PROTEIN COUPLED RECEPTOR 97
Common Name English
H3R
Common Name English
HH3R
Common Name English
Code System Code Type Description
WIKIPEDIA
Histamine H3 receptor
Created by admin on Sat Dec 16 14:49:04 GMT 2023 , Edited by admin on Sat Dec 16 14:49:04 GMT 2023
PRIMARY
PHAROS
Q9Y5N1
Created by admin on Sat Dec 16 14:49:04 GMT 2023 , Edited by admin on Sat Dec 16 14:49:04 GMT 2023
PRIMARY
UNIPROT
Q9Y5N1
Created by admin on Sat Dec 16 14:49:04 GMT 2023 , Edited by admin on Sat Dec 16 14:49:04 GMT 2023
PRIMARY
FDA UNII
D9SCP0G3HF
Created by admin on Sat Dec 16 14:49:04 GMT 2023 , Edited by admin on Sat Dec 16 14:49:04 GMT 2023
PRIMARY
Glycosylation Type HUMAN
Glycosylation Link Type Site
N 1_11
Related Record Type Details
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Structure of IMMETHRIDINE
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Structure of ABT-239
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It was ultimately dropped from human trials after showing the dangerous cardiac side effect of QT prolongation
Structure of ENERISANT
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Structure of CLOBENPROPIT
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Structure of CIPRALISANT
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Structure of VUF-5681
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Could have partial agonist activity. 3H-cAMP accumulation
IC50
Structure of MITAPIVAT
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BINDING ASSAY
IC50
Structure of LML-134
INVERSE AGONIST->TARGET
cAMP functional assay
Ki
Structure of PF-03654746
INHIBITOR -> TARGET
Structure of A-349821
INHIBITOR -> TARGET
Structure of CIPROXIFAN
INHIBITOR -> TARGET
Structure of PITOLISANT
INVERSE AGONIST->TARGET
Structure of SAMELISANT
INVERSE AGONIST->TARGET
Structure of MITAPIVAT
INVERSE AGONIST->TARGET
IC50
Structure of NERATINIB
INHIBITOR->OFF-TARGET
Structure of APD-916
INVERSE AGONIST->TARGET
Structure of THIOPERAMIDE
INHIBITOR -> TARGET
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT CHEMICAL
NIH
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