SOLANEZUMAB

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Sat Dec 16 09:10:53 UTC 2023` Edited by `admin` on `Sat Dec 16 09:10:53 UTC 2023`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG4
Sequence Origin	HUMANIZED MOUSE
Sequence Type	COMPLETE
Record UNII	5D6PWO0333
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

SOLANEZUMAB

Official Name

English

solanezumab [INN]

Common Name

English

IMMUNOGLOBULIN G1, ANTI-(HUMAN .BETA.-AMYLOID) (HUMAN-MOUSE MONOCLONAL LY2062430 HEAVY CHAIN), DISULFIDE WITH HUMAN-MOUSE MONOCLONAL LY2062430 LIGHT CHAIN, DIMER

Common Name

English

LY2062430

Code

English

SOLANEZUMAB [JAN]

Common Name

English

LY-2062430

Code

English

IMMUNOGLOBULIN G1, ANTI-(HUMAN .BETA.-AMYLOID PEPTIDE) (HUMANIZED MONOCLONAL LY2062430 HEAVY CHAIN, DISULFIDE WITH HUMANIZED MONOCLONAL LY2062430 LIGHT CHAIN, DIMER)

Common Name

English

Solanezumab [WHO-DD]

Common Name

English

IMMUNOGLOBULIN G1, ANTI-(HUMAN .BETA.-AMYLOID PEPTIDE) (HUMANIZED MONOCLONAL LY2062430 HEAVY CHAIN, DISULPHIDE WITH HUMANIZED MONOCLONAL LY2062430 LIGHT CHAIN, DIMER)

Common Name

English

IMMUNOGLOBULIN G1, ANTI-(HUMAN .BETA.-AMYLOID) (HUMAN-MOUSE MONOCLONAL LY2062430 HEAVY CHAIN), DISULPHIDE WITH HUMAN-MOUSE MONOCLONAL LY2062430 LIGHT CHAIN, DIMER

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C20401

Created by admin on Sat Dec 16 09:10:53 UTC 2023 , Edited by admin on Sat Dec 16 09:10:53 UTC 2023

Code System Code Type Description

EVMPD

SUB37126

Created by admin on Sat Dec 16 09:10:53 UTC 2023 , Edited by admin on Sat Dec 16 09:10:53 UTC 2023

PRIMARY

ChEMBL

CHEMBL1743072

Created by admin on Sat Dec 16 09:10:53 UTC 2023 , Edited by admin on Sat Dec 16 09:10:53 UTC 2023

PRIMARY

DRUG BANK

DB11756

Created by admin on Sat Dec 16 09:10:53 UTC 2023 , Edited by admin on Sat Dec 16 09:10:53 UTC 2023

PRIMARY

CAS

955085-14-0

Created by admin on Sat Dec 16 09:10:53 UTC 2023 , Edited by admin on Sat Dec 16 09:10:53 UTC 2023

PRIMARY

FDA UNII

5D6PWO0333

Created by admin on Sat Dec 16 09:10:53 UTC 2023 , Edited by admin on Sat Dec 16 09:10:53 UTC 2023

PRIMARY

INN

9097

Created by admin on Sat Dec 16 09:10:53 UTC 2023 , Edited by admin on Sat Dec 16 09:10:53 UTC 2023

PRIMARY

NCI_THESAURUS

C88585

Created by admin on Sat Dec 16 09:10:53 UTC 2023 , Edited by admin on Sat Dec 16 09:10:53 UTC 2023

PRIMARY

WIKIPEDIA

SOLANEZUMAB

Created by admin on Sat Dec 16 09:10:53 UTC 2023 , Edited by admin on Sat Dec 16 09:10:53 UTC 2023

PRIMARY

From	To
1_22	1_96
1_139	1_195
1_256	1_316
1_362	1_420
2_22	2_96
2_139	2_195
2_256	2_316
2_362	2_420
3_23	3_93
3_139	3_199
4_23	4_93
4_139	4_199
1_215	3_219
2_215	4_219
1_221	2_221
1_224	2_224

Glycosylation Link Type	Site
N	1_292
N	2_292

Related Record Type Details


					042A8N37WH

HUMAN .BETA.-AMYLOID PEPTIDE (1-42)

TARGET->LIGAND

Comments:

Designed to increase the clearance from the brain of soluble Aβ, peptides that may lead to toxic effects in the synapses and precede the deposition of fibrillary amyloid.

Amount:


					13539D6GO8

HUMAN .BETA.-AMYLOID PEPTIDE (1-40)

TARGET->LIGAND

Comments:

Designed to increase the clearance from the brain of soluble Aβ, peptides that may lead to toxic effects in the synapses and precede the deposition of fibrillary amyloid.

Amount:

Related Record Type Details


					5D6PWO0333

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL