HUMAN .BETA.-AMYLOID PEPTIDE (1-42)

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Sat Dec 16 09:55:51 GMT 2023` Edited by `admin` on `Sat Dec 16 09:55:51 GMT 2023`
Protein Sub Type
Sequence Type	COMPLETE
Record UNII	042A8N37WH
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

HUMAN .BETA.-AMYLOID PEPTIDE (1-42)

Common Name

English

ASP-ALA-GLU-PHE-ARG-HIS-ASP-SER-GLY-TYR-GLU-VAL-HIS-HIS-GLN-LYS-LEU-VAL-PHE-PHE-ALA-GLU-ASP-VAL-GLY-SER-ASN-LYS-GLY-ALA-ILE-ILE-GLY-LEU-MET-VAL-GLY-GLY-VAL-VAL-ILE-ALA

Common Name

English

ABETA 1-42

Common Name

English

A.BETA.42

Common Name

English

A.BETA.1-42

Common Name

English

AMYLOID .BETA. 1-42

Common Name

English

GLYCOPROTEIN, AMYLOID A4 (HUMAN CLONE .LAMBDA.APCP168I4 N-TERMINAL 42-AMINO-ACID FRAGMENT)

Common Name

English

PEPTIDE .BETA. (HUMAN AMYLOID)

Common Name

English

A.BETA.42 [MI]

Common Name

English

Code System Code Type Description

CHEBI

64647

Created by admin on Sat Dec 16 09:55:51 GMT 2023 , Edited by admin on Sat Dec 16 09:55:51 GMT 2023

PRIMARY

FDA UNII

042A8N37WH

Created by admin on Sat Dec 16 09:55:51 GMT 2023 , Edited by admin on Sat Dec 16 09:55:51 GMT 2023

PRIMARY

PUBCHEM

57339251

Created by admin on Sat Dec 16 09:55:51 GMT 2023 , Edited by admin on Sat Dec 16 09:55:51 GMT 2023

PRIMARY

MERCK INDEX

m1878

Created by admin on Sat Dec 16 09:55:51 GMT 2023 , Edited by admin on Sat Dec 16 09:55:51 GMT 2023

PRIMARY

Merck Index

EPA CompTox

DTXSID70856172

Created by admin on Sat Dec 16 09:55:51 GMT 2023 , Edited by admin on Sat Dec 16 09:55:51 GMT 2023

PRIMARY

CAS

107761-42-2

Created by admin on Sat Dec 16 09:55:51 GMT 2023 , Edited by admin on Sat Dec 16 09:55:51 GMT 2023

PRIMARY

Related Record Type Details


					GUU94434KC

PAL 1-15

VACCINE ANTIGEN->TARGET

Amount:


					UH32L7RML6

LIGAND->TARGET

Comments:

Targets soluble Aβ monomer to shift oligomer equilibrium and prevent direct neurotoxicity from soluble forms.


					C35RF1MWQZ

INHIBITOR OF RELEASE->TARGET

Amount:


					6W15Z5R0RU

FLORBETAPIR F-18

RADIOLIGAND->TARGET


					5D6PWO0333

LIGAND->TARGET

Comments:

Designed to increase the clearance from the brain of soluble Aβ, peptides that may lead to toxic effects in the synapses and precede the deposition of fibrillary amyloid.

Amount:


					F7MN148019

RN-6G

INHIBITOR -> TARGET


					BEX3397O3Z

D3-FLORBETAPIR F-18

RADIOLIGAND->TARGET

Amount:


					1051LN7FLM

SEN-1176

INHIBITOR OF AGGREGATION->TARGET

Comments:

Inhibitor of neuroinflammation caused by Aβ1–42-induced macrophage production of nitric oxide, TNF-alpha, IL-1beta, and IL-6.

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:SEQUENCE(CALCULATED)	CHEMICAL