Belrestotug

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 11:26:03 GMT 2025` Edited by `admin` on `Wed Apr 02 11:26:03 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1\|KAPPA
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	59HAW3EQ4C
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

CLONE 31282

Preferred Name

English

Belrestotug

Official Name

English

GSK4428859A

Code

English

WB2127

Code

English

EOS884448

Code

English

RECOMBINANT FULLY HUMAN IGG1 KAPPA ANTI-TIGIT MONOCLONAL ANTIBODY EOS-448

Common Name

English

EOS-884448

Code

English

Belrestotug [WHO-DD]

Common Name

English

belrestotug [INN]

Common Name

English

BELRESTOTUG [USAN]

Common Name

English

IMMUNOGLOBULIN G1, ANTI-(HUMAN RECEPTOR TIGIT) (HUMAN MONOCLONAL EOS884448 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN MONOCLONAL EOS884448 .KAPPA.-CHAIN, DIMER

Common Name

English

WB-2127

Code

English

GSK-4428859A

Code

English

EOS-448

Code

English

Code System Code Type Description

USAN

JK-184

Created by admin on Wed Apr 02 11:26:03 GMT 2025 , Edited by admin on Wed Apr 02 11:26:03 GMT 2025

PRIMARY

FDA UNII

59HAW3EQ4C

Created by admin on Wed Apr 02 11:26:03 GMT 2025 , Edited by admin on Wed Apr 02 11:26:03 GMT 2025

PRIMARY

INN

12360

Created by admin on Wed Apr 02 11:26:03 GMT 2025 , Edited by admin on Wed Apr 02 11:26:03 GMT 2025

PRIMARY

CAS

2574438-65-4

Created by admin on Wed Apr 02 11:26:03 GMT 2025 , Edited by admin on Wed Apr 02 11:26:03 GMT 2025

PRIMARY

SMS_ID

300000004520

Created by admin on Wed Apr 02 11:26:03 GMT 2025 , Edited by admin on Wed Apr 02 11:26:03 GMT 2025

PRIMARY

NCI_THESAURUS

C176746

Created by admin on Wed Apr 02 11:26:03 GMT 2025 , Edited by admin on Wed Apr 02 11:26:03 GMT 2025

PRIMARY

From	To
1_22	1_96
2_22	2_96
2_148	2_204
2_224	4_215
2_265	2_325
1_148	1_204
2_371	2_429
3_23	3_89
3_135	3_195
4_23	4_89
4_135	4_195
1_224	3_215
1_230	2_230
1_233	2_233
1_265	1_325
1_371	1_429

Glycosylation Link Type	Site
N	1_301
N	2_301

Related Record Type Details


					59HAW3EQ4C

ACTIVE MOIETY

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO ACID REMOVAL	[1_451] [2_451]	C-TERMINUS		Amount:	LYSINE	K3Z4F929H6
AMINO_ACID_SUBSTITUTION	[1_1] [2_1]	N-TERMINUS		Amount:	PIDOLIC ACID	SZB83O1W42

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL