Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C19H24N2OS |
| Molecular Weight | 328.472 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CCN(CC)CCSC(=O)N(C1=CC=CC=C1)C2=CC=CC=C2
InChI
InChIKey=BZGIPVGCJGXQTA-UHFFFAOYSA-N
InChI=1S/C19H24N2OS/c1-3-20(4-2)15-16-23-19(22)21(17-11-7-5-8-12-17)18-13-9-6-10-14-18/h5-14H,3-4,15-16H2,1-2H3
| Molecular Formula | C19H24N2OS |
| Molecular Weight | 328.472 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Phencarbamide is an anti-spasmodic and anticholinergic drug used during parturition. It has a specific antispasmodic action on the smooth muscle, both directly like papaverine and through the autonomic nervous system (atropine effect). It has also an analgesic effect of its own. Side-effects generally associated with the atropine group of drugs.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Propranolol-bunolol and phencarbamide in chloroform-induced ventricular fibrillation in mice. | 1973-06 |
|
| [Colorimetric determination of phencarbamide and its hydrochloride and naphthalene disulfonate salts]. | 1971-11 |
|
| Anticonvulsant effect of phencarbamide and its modification by reserpine and tranylcypromine. | 1971-03 |
|
| A study of the antiarrhythmic and local anaesthetic actions of phencarbamide. | 1970-05 |
|
| [Spasmolytic effect of phencarbamide on the uterine cervix during early puerperium]. | 1966-08-26 |
|
| [PRACTICAL EXPERIENCES WITH THE SPASMOLYTIC AGENT ESCORPAL IN OBSTETRICS]. | 1965-01-30 |
|
| [SPASMOLYSIS IN OBSTETRICS: CLINICAL EXPERIENCE WITH PHENCARBAMIDE]. | 1964-09-26 |
|
| [EXPERIENCES WITH A NEW SPASMOLYTIC AGENT (ESCORPAL) IN OBSTETRICS]. | 1964-06-20 |
|
| [PHENCARBAMIDE, A NEW SPASMOLYTIC COMBINED WITH DOLVIRAN]. | 1964-06 |
|
| [On the pharmacology of the uterine action of phencarbamide]. | 1963 |
|
| [On the clinical experiences with the spasmolytic Bayer 1355 (phencarbamide) in obstetrics]. | 1963 |
| Substance Class |
Chemical
Created
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admin
on
Edited
Mon Mar 31 18:30:27 GMT 2025
by
admin
on
Mon Mar 31 18:30:27 GMT 2025
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| Record UNII |
59H17J9F1B
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| Record Status |
Validated (UNII)
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| Classification Tree | Code System | Code | ||
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NCI_THESAURUS |
C29704
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NCI_THESAURUS |
C29696
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| Code System | Code | Type | Description | ||
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C66369
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SUB07546MIG
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100000081246
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6008
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223-103-4
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m395
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PRIMARY | Merck Index | ||
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59H17J9F1B
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3735-90-8
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CHEMBL2107472
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1324
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DTXSID80190796
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SALT/SOLVATE -> PARENT |
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ACTIVE MOIETY |
