Details
Stereochemistry | ACHIRAL |
Molecular Formula | C19H24N2OS.C10H8O6S2 |
Molecular Weight | 616.769 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
OS(=O)(=O)C1=CC=CC2=C(C=CC=C12)S(O)(=O)=O.CCN(CC)CCSC(=O)N(C3=CC=CC=C3)C4=CC=CC=C4
InChI
InChIKey=ZZNARJBYZHRHKJ-UHFFFAOYSA-N
InChI=1S/C19H24N2OS.C10H8O6S2/c1-3-20(4-2)15-16-23-19(22)21(17-11-7-5-8-12-17)18-13-9-6-10-14-18;11-17(12,13)9-5-1-3-7-8(9)4-2-6-10(7)18(14,15)16/h5-14H,3-4,15-16H2,1-2H3;1-6H,(H,11,12,13)(H,14,15,16)
Molecular Formula | C10H8O6S2 |
Molecular Weight | 288.297 |
Charge | 0 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
Molecular Formula | C19H24N2OS |
Molecular Weight | 328.472 |
Charge | 0 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
Phencarbamide is an anti-spasmodic and anticholinergic drug used during parturition. It has a specific antispasmodic action on the smooth muscle, both directly like papaverine and through the autonomic nervous system (atropine effect). It has also an analgesic effect of its own. Side-effects generally associated with the atropine group of drugs.
Approval Year
PubMed
Title | Date | PubMed |
---|---|---|
[On the pharmacology of the uterine action of phencarbamide]. | 1963 |
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[On the clinical experiences with the spasmolytic Bayer 1355 (phencarbamide) in obstetrics]. | 1963 |
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[PHENCARBAMIDE, A NEW SPASMOLYTIC COMBINED WITH DOLVIRAN]. | 1964 Jun |
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[EXPERIENCES WITH A NEW SPASMOLYTIC AGENT (ESCORPAL) IN OBSTETRICS]. | 1964 Jun 20 |
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[SPASMOLYSIS IN OBSTETRICS: CLINICAL EXPERIENCE WITH PHENCARBAMIDE]. | 1964 Sep 26 |
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[PRACTICAL EXPERIENCES WITH THE SPASMOLYTIC AGENT ESCORPAL IN OBSTETRICS]. | 1965 Jan 30 |
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[Spasmolytic effect of phencarbamide on the uterine cervix during early puerperium]. | 1966 Aug 26 |
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A study of the antiarrhythmic and local anaesthetic actions of phencarbamide. | 1970 May |
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Anticonvulsant effect of phencarbamide and its modification by reserpine and tranylcypromine. | 1971 Mar |
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[Colorimetric determination of phencarbamide and its hydrochloride and naphthalene disulfonate salts]. | 1971 Nov |
|
Propranolol-bunolol and phencarbamide in chloroform-induced ventricular fibrillation in mice. | 1973 Jun |
Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 11:24:27 GMT 2023
by
admin
on
Sat Dec 16 11:24:27 GMT 2023
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Record UNII |
HXQ3ENP4FG
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Record Status |
Validated (UNII)
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Record Version |
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72017-58-4
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100000087483
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20057134
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36253-62-0
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m395
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SUB02111MIG
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PARENT -> SALT/SOLVATE |
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ACTIVE MOIETY |