CLOFEVERINE

Details

Stereochemistry	RACEMIC
Molecular Formula	C16H16ClNO3
Molecular Weight	305.756
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

OC1=CC2=C(C=C1O)C(COC3=CC=C(Cl)C=C3)NCC2

InChI

InChIKey=GVALVWDQPXGPCE-UHFFFAOYSA-N

InChI=1S/C16H16ClNO3/c17-11-1-3-12(4-2-11)21-9-14-13-8-16(20)15(19)7-10(13)5-6-18-14/h1-4,7-8,14,18-20H,5-6,9H2

HIDE SMILES / InChI

Molecular Formula	C16H16ClNO3
Molecular Weight	305.756
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Description
Sources: https://books.google.ru/books?id=z_8kBQAAQBAJ&pg=PA316&lpg=PA316

Clofeverine is a compound synthesized by the Japanese company Fujisawa Pharmaceutical. Clofeverine is a highly selective relaxant for gastrointestinal smooth muscles with a beta-receptor stimulative nature. On isolated ileum, the inhibitory effect of clofeverine for spontaneous motility was comparable to that of isoproterenol and 100 times higher than that of papaverine.

Approval Year

Patents

Substance Class	Chemical Created by `admin` on `Wed Apr 02 06:52:42 GMT 2025` Edited by `admin` on `Wed Apr 02 06:52:42 GMT 2025`
Record UNII	584A0O55XM
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

6,7-ISOQUINOLINEDIOL, 1-((4-CHLOROPHENOXY)METHYL)-1,2,3,4-TETRAHYDRO-

Preferred Name

English

CLOFEVERINE

Official Name

English

1-((P-CHLOROPHENOXY)METHYL)-1,2,3,4-TETRAHYDRO-6,7-ISOQUINOLINEDIOL

Common Name

English

clofeverine [INN]

Common Name

English

CLOFEVERINE [JAN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C66880