Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C18H19NO3 |
| Molecular Weight | 297.3484 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 3 / 3 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
COC1=CC=C2[C@H]3CC4=CC=C(O)C5=C4[C@@]2(CCN3C)[C@H]1O5
InChI
InChIKey=ZKLXUUYLEHCAMF-UUWFMWQGSA-N
InChI=1S/C18H19NO3/c1-19-8-7-18-11-4-6-14(21-2)17(18)22-16-13(20)5-3-10(15(16)18)9-12(11)19/h3-6,12,17,20H,7-9H2,1-2H3/t12-,17+,18+/m1/s1
| Molecular Formula | C18H19NO3 |
| Molecular Weight | 297.3484 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 3 / 3 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| N-demethylation of N-methyl alkaloids with ferrocene. | 2010-08-01 |
|
| No hyperalgesia following opioid withdrawal after the oripavine derivative etorphine compared to remifentanil and sufentanil. | 2010-02 |
|
| Biochemistry and occurrence of o-demethylation in plant metabolism. | 2010 |
|
| Isolation and identification of unique marker compounds from the Tasmanian poppy Papaver somniferum N. Implications for the identification of illicit heroin of Tasmanian origin. | 2008-03-05 |
|
| Differentiation of opium and poppy straw using capillary electrophoresis and pattern recognition techniques. | 2007-12-12 |
|
| Cinnamoyl derivatives of 7alpha-aminomethyl-6,14-endo-ethanotetrahydrothebaine and 7alpha-aminomethyl-6,14-endo-ethanotetrahydrooripavine and related opioid ligands. | 2007-10-18 |
|
| A hybrid FIA/HPLC system incorporating monolithic column chromatography. | 2007-09-26 |
|
| Designation of oripavine as a basic class of controlled substance. Final rule. | 2007-09-24 |
|
| Live cell monitoring of mu-opioid receptor-mediated G-protein activation reveals strong biological activity of close morphine biosynthetic precursors. | 2007-09-14 |
|
| Rapid determination of Papaver somniferum alkaloids in process streams using monolithic column high-performance liquid chromatography with chemiluminescence detection. | 2007-07-30 |
|
| Thienorphine: receptor binding and behavioral effects in rhesus monkeys. | 2007-04 |
|
| Determination of opiate alkaloids in process liquors using capillary electrophoresis. | 2007-02-19 |
|
| WHO Expert Committee on Drug Dependence. | 2006 |
|
| A rapid and reliable solid-phase extraction method for high-performance liquid chromatographic analysis of opium alkaloids from papaver plants. | 2005-11 |
|
| Submolecular partitioning of morphine hydrate based on its experimental charge density at 25 K. | 2005-08 |
|
| BU74, a complex oripavine derivative with potent kappa opioid receptor agonism and delayed opioid antagonism. | 2005-02-21 |
|
| RNAi-mediated replacement of morphine with the nonnarcotic alkaloid reticuline in opium poppy. | 2004-12 |
|
| Analgesia: morphine-pathway block in top1 poppies. | 2004-09-23 |
|
| Separation of opiate alkaloids by electrokinetic chromatography with sulfated-cyclodextrin as a pseudo-stationary phase. | 2003-01-24 |
|
| Characterization of opiates, neuroleptics, and synthetic analogs at ORL1 and opioid receptors. | 2001-09-28 |
|
| Comparison of pharmacological activities of buprenorphine and norbuprenorphine: norbuprenorphine is a potent opioid agonist. | 2001-05 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 22:08:23 GMT 2025
by
admin
on
Mon Mar 31 22:08:23 GMT 2025
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| Record UNII |
575AOU51CR
|
| Record Status |
Validated (UNII)
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| Record Version |
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Preferred Name | English | ||
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| Classification Tree | Code System | Code | ||
|---|---|---|---|---|
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DEA NO. |
9330
Created by
admin on Mon Mar 31 22:08:23 GMT 2025 , Edited by admin on Mon Mar 31 22:08:23 GMT 2025
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| Code System | Code | Type | Description | ||
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467-04-9
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DTXSID10196908
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m8232
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PRIMARY | Merck Index | ||
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5462306
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PRIMARY | |||
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8324
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PRIMARY | |||
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ORIPAVINE
Created by
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207-385-6
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PRIMARY | |||
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575AOU51CR
Created by
admin on Mon Mar 31 22:08:23 GMT 2025 , Edited by admin on Mon Mar 31 22:08:23 GMT 2025
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PRIMARY |
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|---|---|---|---|---|
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SALT/SOLVATE -> PARENT |
APPROXIMATE PURE ANHYDROUS DRUG CONTENT (IN PERCENT)
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PARENT -> IMPURITY | |||
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PARENT -> IMPURITY |
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PARENT -> IMPURITY |
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
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PARENT -> IMPURITY |
CHROMATOGRAPHIC PURITY (HPLC/UV)
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