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Details

Stereochemistry ABSOLUTE
Molecular Formula C18H19NO3
Molecular Weight 297.3484
Optical Activity UNSPECIFIED
Defined Stereocenters 3 / 3
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ORIPAVINE

SMILES

[H][C@@]12OC3=C(O)C=CC4=C3[C@@]15CCN(C)[C@]([H])(C4)C5=CC=C2OC

InChI

InChIKey=ZKLXUUYLEHCAMF-UUWFMWQGSA-N
InChI=1S/C18H19NO3/c1-19-8-7-18-11-4-6-14(21-2)17(18)22-16-13(20)5-3-10(15(16)18)9-12(11)19/h3-6,12,17,20H,7-9H2,1-2H3/t12-,17+,18+/m1/s1

HIDE SMILES / InChI

Molecular Formula C18H19NO3
Molecular Weight 297.3484
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 3 / 3
E/Z Centers 0
Optical Activity UNSPECIFIED

Approval Year

PubMed

PubMed

TitleDatePubMed
Comparison of pharmacological activities of buprenorphine and norbuprenorphine: norbuprenorphine is a potent opioid agonist.
2001 May
Characterization of opiates, neuroleptics, and synthetic analogs at ORL1 and opioid receptors.
2001 Sep 28
Separation of opiate alkaloids by electrokinetic chromatography with sulfated-cyclodextrin as a pseudo-stationary phase.
2003 Jan 24
A rapid and reliable solid-phase extraction method for high-performance liquid chromatographic analysis of opium alkaloids from papaver plants.
2005 Nov
Rapid determination of Papaver somniferum alkaloids in process streams using monolithic column high-performance liquid chromatography with chemiluminescence detection.
2007 Jul 30
Cinnamoyl derivatives of 7alpha-aminomethyl-6,14-endo-ethanotetrahydrothebaine and 7alpha-aminomethyl-6,14-endo-ethanotetrahydrooripavine and related opioid ligands.
2007 Oct 18
Designation of oripavine as a basic class of controlled substance. Final rule.
2007 Sep 24
A hybrid FIA/HPLC system incorporating monolithic column chromatography.
2007 Sep 26
Biochemistry and occurrence of o-demethylation in plant metabolism.
2010
N-demethylation of N-methyl alkaloids with ferrocene.
2010 Aug 1
No hyperalgesia following opioid withdrawal after the oripavine derivative etorphine compared to remifentanil and sufentanil.
2010 Feb
Patents
Substance Class Chemical
Created
by admin
on Sat Dec 16 08:31:19 GMT 2023
Edited
by admin
on Sat Dec 16 08:31:19 GMT 2023
Record UNII
575AOU51CR
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ORIPAVINE
MI  
Common Name English
CODEINE HYDROCHLORIDE DIHYDRATE IMPURITY L [EP IMPURITY]
Common Name English
MORPHINE SULFATE IMPURITY C [EP IMPURITY]
Common Name English
IDS-NO-010
Code English
CODEINE MONOHYDRATE IMPURITY L [EP IMPURITY]
Common Name English
3-O-DEMETHYLTHEBAINE
Common Name English
MORPHINE HYDROCHLORIDE IMPURITY C [EP IMPURITY]
Common Name English
ORIPAVINE [MI]
Common Name English
MORPHINAN-3-OL, 6,7,8,14-TETRADEHYDRO-4,5-EPOXY-6-METHOXY-17-METHYL-, (5.ALPHA.)-
Systematic Name English
CODEINE PHOSPHATE HEMIHYDRATE IMPURITY L [EP IMPURITY]
Common Name English
6,7,8,14-TETRADEHYDRO-4,5.ALPHA.-EPOXY-6-METHOXY-17-METHYLMORPHINAN-3-OL
Systematic Name English
Classification Tree Code System Code
DEA NO. 9330
Created by admin on Sat Dec 16 08:31:19 GMT 2023 , Edited by admin on Sat Dec 16 08:31:19 GMT 2023
Code System Code Type Description
CAS
467-04-9
Created by admin on Sat Dec 16 08:31:19 GMT 2023 , Edited by admin on Sat Dec 16 08:31:19 GMT 2023
PRIMARY
EPA CompTox
DTXSID10196908
Created by admin on Sat Dec 16 08:31:19 GMT 2023 , Edited by admin on Sat Dec 16 08:31:19 GMT 2023
PRIMARY
MERCK INDEX
m8232
Created by admin on Sat Dec 16 08:31:19 GMT 2023 , Edited by admin on Sat Dec 16 08:31:19 GMT 2023
PRIMARY Merck Index
PUBCHEM
5462306
Created by admin on Sat Dec 16 08:31:19 GMT 2023 , Edited by admin on Sat Dec 16 08:31:19 GMT 2023
PRIMARY
HSDB
8324
Created by admin on Sat Dec 16 08:31:19 GMT 2023 , Edited by admin on Sat Dec 16 08:31:19 GMT 2023
PRIMARY
WIKIPEDIA
ORIPAVINE
Created by admin on Sat Dec 16 08:31:19 GMT 2023 , Edited by admin on Sat Dec 16 08:31:19 GMT 2023
PRIMARY
ECHA (EC/EINECS)
207-385-6
Created by admin on Sat Dec 16 08:31:19 GMT 2023 , Edited by admin on Sat Dec 16 08:31:19 GMT 2023
PRIMARY
FDA UNII
575AOU51CR
Created by admin on Sat Dec 16 08:31:19 GMT 2023 , Edited by admin on Sat Dec 16 08:31:19 GMT 2023
PRIMARY
Related Record Type Details
SALT/SOLVATE -> PARENT
APPROXIMATE PURE ANHYDROUS DRUG CONTENT (IN PERCENT)
Related Record Type Details
PARENT -> IMPURITY
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
PARENT -> IMPURITY
PARENT -> IMPURITY
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
PARENT -> IMPURITY
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
PARENT -> IMPURITY
For the calculation of contents, multiply the peak areas by 0.4
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP