ORIPAVINE HYDROCHLORIDE

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C18H19NO3.ClH
Molecular Weight	333.809
Optical Activity	UNSPECIFIED
Defined Stereocenters	3 / 3
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

Cl.[H][C@@]12OC3=C(O)C=CC4=C3[C@@]15CCN(C)[C@]([H])(C4)C5=CC=C2OC

InChI

InChIKey=OGVCGIJVSVSIEL-HIMTYSBHSA-N

InChI=1S/C18H19NO3.ClH/c1-19-8-7-18-11-4-6-14(21-2)17(18)22-16-13(20)5-3-10(15(16)18)9-12(11)19;/h3-6,12,17,20H,7-9H2,1-2H3;1H/t12-,17+,18+;/m1./s1

HIDE SMILES / InChI

Molecular Formula	ClH
Molecular Weight	36.461
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C18H19NO3
Molecular Weight	297.3484
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	3 / 3
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

PubMed

Title	Date	PubMed
Comparison of pharmacological activities of buprenorphine and norbuprenorphine: norbuprenorphine is a potent opioid agonist.	2001 May	11303059
Characterization of opiates, neuroleptics, and synthetic analogs at ORL1 and opioid receptors.	2001 Sep 28	11779034
Separation of opiate alkaloids by electrokinetic chromatography with sulfated-cyclodextrin as a pseudo-stationary phase.	2003 Jan 24	12580518
RNAi-mediated replacement of morphine with the nonnarcotic alkaloid reticuline in opium poppy.	2004 Dec	15543134
Analgesia: morphine-pathway block in top1 poppies.	2004 Sep 23	15386001
Submolecular partitioning of morphine hydrate based on its experimental charge density at 25 K.	2005 Aug	16041094
BU74, a complex oripavine derivative with potent kappa opioid receptor agonism and delayed opioid antagonism.	2005 Feb 21	15733546
A rapid and reliable solid-phase extraction method for high-performance liquid chromatographic analysis of opium alkaloids from papaver plants.	2005 Nov	16272729
WHO Expert Committee on Drug Dependence.	2006	17373571
Thienorphine: receptor binding and behavioral effects in rhesus monkeys.	2007 Apr	17220427
Differentiation of opium and poppy straw using capillary electrophoresis and pattern recognition techniques.	2007 Dec 12	18022406
Determination of opiate alkaloids in process liquors using capillary electrophoresis.	2007 Feb 19	17097256
Rapid determination of Papaver somniferum alkaloids in process streams using monolithic column high-performance liquid chromatography with chemiluminescence detection.	2007 Jul 30	17658308
Cinnamoyl derivatives of 7alpha-aminomethyl-6,14-endo-ethanotetrahydrothebaine and 7alpha-aminomethyl-6,14-endo-ethanotetrahydrooripavine and related opioid ligands.	2007 Oct 18	17887741
Live cell monitoring of mu-opioid receptor-mediated G-protein activation reveals strong biological activity of close morphine biosynthetic precursors.	2007 Sep 14	17616524
Designation of oripavine as a basic class of controlled substance. Final rule.	2007 Sep 24	17912784
A hybrid FIA/HPLC system incorporating monolithic column chromatography.	2007 Sep 26	17903475
Isolation and identification of unique marker compounds from the Tasmanian poppy Papaver somniferum N. Implications for the identification of illicit heroin of Tasmanian origin.	2008 Mar 5	17765420
Biochemistry and occurrence of o-demethylation in plant metabolism.	2010	21423357
N-demethylation of N-methyl alkaloids with ferrocene.	2010 Aug 1	20584607
No hyperalgesia following opioid withdrawal after the oripavine derivative etorphine compared to remifentanil and sufentanil.	2010 Feb	20077594

Patents

Substance Class	Chemical Created by `admin` on `Sat Dec 16 10:28:52 GMT 2023` Edited by `admin` on `Sat Dec 16 10:28:52 GMT 2023`
Record UNII	HRR7PQ2JHN
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

ORIPAVINE HYDROCHLORIDE

Common Name

English

MORPHINAN-3-OL, 6,7,8,14-TETRADEHYDRO-4,5.ALPHA.-EPOXY-6-METHOXY-17-METHYL-, HYDROCHLORIDE

Systematic Name

English

MORPHINAN-3-OL, 6,7,8,14-TETRADEHYDRO-4,5-EPOXY-6-METHOXY-17-METHYL-, HYDROCHLORIDE, (5.ALPHA.)-

Systematic Name

English

MORPHINAN-3-OL, 6,7,8,14-TETRADEHYDRO-4,5-EPOXY-6-METHOXY-17-METHYL-, HYDROCHLORIDE (1:1), (5.ALPHA.)-

Systematic Name

English

(4R,7AR,12BS)-7-METHOXY-3-METHYL-2,4,7A,13-TETRAHYDRO-1H-4,12-METHANOBENZOFURO(3,2-E)ISOQUINOLIN-9-OL;HYDROCHLORIDE

Systematic Name

English

Code System Code Type Description

FDA UNII

HRR7PQ2JHN

Created by admin on Sat Dec 16 10:28:52 GMT 2023 , Edited by admin on Sat Dec 16 10:28:52 GMT 2023

PRIMARY

CAS

6153-40-8

Created by admin on Sat Dec 16 10:28:52 GMT 2023 , Edited by admin on Sat Dec 16 10:28:52 GMT 2023

PRIMARY

PUBCHEM

66760524

Created by admin on Sat Dec 16 10:28:52 GMT 2023 , Edited by admin on Sat Dec 16 10:28:52 GMT 2023

PRIMARY

Related Record Type Details


					575AOU51CR

ORIPAVINE

PARENT -> SALT/SOLVATE

Comments:

APPROXIMATE PURE ANHYDROUS DRUG CONTENT (IN PERCENT)

Amount: