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Details

Stereochemistry RACEMIC
Molecular Formula C19H25N2OS
Molecular Weight 329.48
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 1

SHOW SMILES / InChI
Structure of PROMETHAZINE HYDROXYETHYL

SMILES

CC(CN1C2=C(SC3=C1C=CC=C3)C=CC=C2)[N+](C)(C)CCO

InChI

InChIKey=PDSVTRQOBUIQBQ-UHFFFAOYSA-N
InChI=1S/C19H25N2OS/c1-15(21(2,3)12-13-22)14-20-16-8-4-6-10-18(16)23-19-11-7-5-9-17(19)20/h4-11,15,22H,12-14H2,1-3H3/q+1

HIDE SMILES / InChI
Molecular Formula C19H24N2OS
Molecular Weight 328.472
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry MIXED
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 0
Optical Activity ( + / - )

Description

Promethazine hydroxyethyl quaternary derivative of promethazine with antihistamine and anticholinergic properties. The drug lacked the sedative properties of promethazine. It was used in the clinic under tradename Aprobit.

Approval Year

Unknown
139,594
Substance Class Chemical
Record UNII
571559SLAJ
Record Status Validated (UNII)
Record Version
NIH
NCATS
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