PROMETHAZINE HYDROXYETHYL

Details

Stereochemistry	RACEMIC
Molecular Formula	C19H25N2OS
Molecular Weight	329.48
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	1

SHOW SMILES / InChI

Structure Search

SMILES

CC(CN1C2=C(SC3=C1C=CC=C3)C=CC=C2)[N+](C)(C)CCO

InChI

InChIKey=PDSVTRQOBUIQBQ-UHFFFAOYSA-N

InChI=1S/C19H25N2OS/c1-15(21(2,3)12-13-22)14-20-16-8-4-6-10-18(16)23-19-11-7-5-9-17(19)20/h4-11,15,22H,12-14H2,1-3H3/q+1

HIDE SMILES / InChI

Molecular Formula	C19H24N2OS
Molecular Weight	328.472
Charge	0
Count

Stereochemistry	MIXED
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/4386346

Promethazine hydroxyethyl quaternary derivative of promethazine with antihistamine and anticholinergic properties. The drug lacked the sedative properties of promethazine. It was used in the clinic under tradename Aprobit.

Approval Year

Substance Class	Chemical Created by `admin` on `Sat Dec 16 10:44:09 GMT 2023` Edited by `admin` on `Sat Dec 16 10:44:09 GMT 2023`
Record UNII	571559SLAJ
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

PROMETHAZINE HYDROXYETHYL

Common Name

English

N-HYDROXYETHYLPROMETHAZINE

Common Name

English

HYDROXYETHYLPROMETHAZINE

Common Name

English

10H-PHENOTHIAZINE-10-ETHANAMINIUM, N-(2-HYDROXYETHYL)-N,N,.ALPHA.-TRIMETHYL-

Systematic Name

English

AMMONIUM, (2-HYDROXYETHYL)DIMETHYL(1-METHYL-2-PHENOTHIAZIN-10-YLETHYL)-

Systematic Name

English

Classification Tree Code System Code

WHO-ATC

R06AD55