SECOVERINE

Details

Stereochemistry	RACEMIC
Molecular Formula	C22H35NO2
Molecular Weight	345.5188
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCN(CCCC(=O)C1CCCCC1)C(C)CC2=CC=C(OC)C=C2

InChI

InChIKey=WAVYHSURRZBQKO-UHFFFAOYSA-N

InChI=1S/C22H35NO2/c1-4-23(16-8-11-22(24)20-9-6-5-7-10-20)18(2)17-19-12-14-21(25-3)15-13-19/h12-15,18,20H,4-11,16-17H2,1-3H3

HIDE SMILES / InChI

Molecular Formula	C22H35NO2
Molecular Weight	345.5188
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/3758175 | https://www.ncbi.nlm.nih.gov/pubmed/7193020

Secoverine is a selective muscarinic receptor antagonist that was studied as a neurotropic spasmolytic agent. It was shown that the drug had no nicotinolytic or antihistaminic activity, a moderate antisterotonic activity, an inhibiting effect on the noradrenaline uptake mechanism of the vas deferens and marked local anesthetic activity.

Approval Year

PubMed

Title	Date	PubMed
Comparison of the affinity of secoverine for some muscarinic receptors.	1985 Jan-Feb	4006314
Secoverine is a non-selective muscarinic antagonist on rat heart and brain receptors.	1986 Aug 7	3758175

Substance Class	Chemical Created by `admin` on `Fri Dec 15 17:32:04 GMT 2023` Edited by `admin` on `Fri Dec 15 17:32:04 GMT 2023`
Record UNII	512WJG3I0O
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

SECOVERINE

Official Name

English

1-CYCLOHEXYL-4-(ETHYL(P-METHOXY-.ALPHA.-METHYLPHENETHYL)AMINO)-1-BUTANONE

Common Name

English

1-BUTANONE, 1-CYCLOHEXYL-4-(ETHYL(2-(4-METHOXYPHENYL)-1-METHYLETHYL)AMINO)-

Systematic Name

English

secoverine [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29704